Elevated Intraocular Pressure Independently Predicts Long-Term Progression to Advanced Chronic Kidney Disease: A 20-Year Longitudinal Cohort Study [0.03%]
长期进展为晚期慢性肾脏病的升高的眼内压独立预测因素：一项为期20年的纵向队列研究
Riri Oh,Jun Ogino,Yukie Sakuma et al.
Riri Oh et al.
Background: Glaucoma is the leading cause of irreversible blindness worldwide, and chronic kidney disease (CKD) is associated with progression to end-stage renal disease, cardiovascular events, and increased mortality. Al...
Hongxia Fu,Benjamin S Freedman
Hongxia Fu
Polycystic kidney disease (PKD) is commonly inherited as a loss-of-function mutation in PC1 (polycystin-1) or PC2. The molecular functions of polycystins remain uncertain, and therapeutics remain limited for millions of patients. One major ...
Review
Nephron. 2026 Jul 21:1-14. DOI:10.1159/000553552 2026
Sustained terminal complement inhibition on the endothelium with ravulizumab in patients with atypical Haemolytic Uremic Syndrome [0.03%]
长效终端补体抑制剂 ravulizumab 对非典型溶血性尿毒症综合征患者血管内皮细胞的作用
Sara Gastoldi,Elena Bresin,Andrea Pasini et al.
Sara Gastoldi et al.
Introduction: Atypical haemolytic uremic syndrome (aHUS) is a rare and severe form of thrombotic microangiopathy caused by dysregulation of the alternative complement pathway, leading to sustained complement activation at...
Peri-Transplant APOL1 Pore Inhibition in High-Risk Donor Kidneys: A Testable Hypothesis [0.03%]
移植周围高风险供体肾脏APOL1孔隙抑制的假设性研究
Lucas Maciel de Almeida Corrêa,Gabriel Rian Mazur,Clara Belo Gamon Santiago et al.
Lucas Maciel de Almeida Corrêa et al.
ANY ROLE FOR RENAL-DERIVED EXTRACELLULAR VESICLES MANIPULATION FOR CARDIOPROTECTION IN CKD? [0.03%]
肾病患者中肾源性外泌体在心脏保护中的作用有多大？
Aneliya Parvanova,Piero Ruggenenti
Aneliya Parvanova
Clinical and Genetic Epidemiology of Autosomal Dominant Polycystic Kidney Disease among patients incident on first kidney replacement therapy between 1990-2023, in a major hospital in the Northwest of Portugal [0.03%]
1990年至2023年期间西北葡萄牙一家主要医院首次接受肾脏替代治疗的患者中常染色体显性多囊肾病的临床和遗传流行病学特征
Alexandra Silva,Pedro Lisboa Gonçalves,Liliana Capela et al.
Alexandra Silva et al.
Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disease, accounting for 5-10% of incident patients requiring kidney replacement therapy (KRT). Although most cases res...
Lena K Rosenbaek,Adrienne M Assmus,Robert A Fenton
Lena K Rosenbaek
Background: With the rising prevalence of hypertension and the limitations of current treatment and prevention strategies, modifying potassium (K+) intake has emerged as a potential new approach to help control blood pres...
Review
Nephron. 2026 Jul 7:1-23. DOI:10.1159/000553460 2026
The Impact of High-Altitude Acclimatization on Frontal Lobe Executive Function: The Mediating Effect of Creatinine [0.03%]
高海拔习服对前额叶执行功能的影响：血肌酐的中介作用
Hongyan Li,Yonghao Ou,Shenglong Li
Hongyan Li
Objective: Highaltitude hypoxia impairs frontal executive functions. This study examines whether serum creatinine mediates the relationship between altitude acclimatization (AAI) SpO₂/HCT ratio and frontal neural oscill...
Expert Commentary of the Recent International Pediatric Nephrology Association IgA Vasculitis Nephritis Guidelines [0.03%]
国际儿科肾脏病协会IgA肾炎指南专家解读
Manya Raina,Jieji Hu,Shay Tanna et al.
Manya Raina et al.
Acute effects of exercise on the nephron index under different conditions in middle-aged males - a preliminary study [0.03%]
不同条件下运动对中年男性肾小球滤过率急性效应的初步研究
Shotaro Kawakami,Tetsuhiko Yasuno,Saki Kawakami et al.
Shotaro Kawakami et al.
Background and aims: The nephron index provides a non-invasive and theoretical estimate of the functional nephrons based on the assumption that serum fibroblast growth factor 23 (FGF23) concentrations correlate with phosp...