Discovery Pipeline for AKI: Molecules, Mechanisms, Models, and Targets [0.03%]
急性肾损伤的发现途径：分子、机制、模型和靶点
Tanima Chatterjee,Joseph Rutkowski,Danielle E Soranno et al.
Tanima Chatterjee et al.
Background: Acute kidney injury (AKI) represents a multifaceted clinical syndrome marked by precipitous loss of kidney function, high morbidity and mortality, and a strong propensity for progression to chronic kidney dise...
Review
Nephron. 2025 Nov 28:1-16. DOI:10.1159/000549795 2025
Biallelic TMEM72 variants in patients with a nephronophthisis-like phenotype [0.03%]
TMEM72双等位基因变异导致的类似肾小管萎缩症表型患者的临床特征及遗传研究
Laura R Claus,Rozemarijn Snoek,Siebren Faber et al.
Laura R Claus et al.
Introduction: Nephronophthisis (NPHP) is an autosomal recessive kidney disease resulting mainly from primary cilium defects, with unspecific and variable symptoms that can progress to kidney failure needing replacement th...
Exercise intervention in patients with metabolic syndrome and renal disease: a prospective study (EXRED) [0.03%]
代谢综合征并肾病患者运动干预研究（EXRED）
Olav Rivero Martín,Raúl Morales Febles,Patricia I Delgado Mallén et al.
Olav Rivero Martín et al.
Introduction: In patients with chronic kidney disease (CKD) of diverse causes, obesity and metabolic syndrome (MS) accelerate disease progression. Therapeutic exercise could be effective in treating obesity and MS in pati...
Marta Raposo
Marta Raposo
Published Erratum
Nephron. 2025 Nov 26:1. DOI:10.1159/000549041 2025
Outcomes and decision stability in older adults following structured counselling on dialysis vs conservative management for kidney failure: A Prospective Study [0.03%]
系统性咨询与保守治疗对老年肾病患者结局及决策稳定性的对比：一项前瞻性研究
Juan Santacruz,Gloria Del Peso,Helena García-Llana et al.
Juan Santacruz et al.
Background The management of kidney failure in older adults has increasingly adopted patient-centered approaches, with conservative kidney management (CKM) recognized as a valid alternative to dialysis in selected cases. Structured counsell...
COMPARING OUTCOMES OF SPOUSAL KIDNEY TRANSPLANTS WITH LIVING-RELATED DONORS IN DSA-POSITIVE RECIPIENTS: IS THE RISK INCREASED IN HUSBAND-TO-WIFE DONATION? [0.03%]
配型不合受者的配偶供肾移植：丈夫供肾至妻子和妻子供肾至丈夫的手术结果比较
Feride Ozkara,Guldehan Haberal,Haci Hasan Yeter et al.
Feride Ozkara et al.
Introduction: The number of spousal donor transplantation (SDT) has increased since the early 1990s. Although the SDT is performed successfully today, several concerns remain regarding compatibility. In particular, in hus...
Advance Care Planning as Key to Person-Centered Care: A co-design study involving adults with chronic kidney disease, family members and healthcare professionals [0.03%]
以患者为中心的护理的关键在于预先护理规划——包括家庭成员和医护人员在内的慢性肾病成人共同设计研究
Christina Egmose Frandsen,Bettina Trettin,Ingrid Villadsen Kristensen et al.
Christina Egmose Frandsen et al.
Introduction Advance care planning is a process that supports adults at any age or stage of health in understanding and sharing their personal values, life goals, and preferences regarding future medical care . Advance care planning is reco...
Decisional regret in adults facing treatment choices for kidney failure: a systematic review [0.03%]
透析成人治疗决策后悔的系统评价
Ingrid Bispo,Mariana Bressan,Francisca Rego et al.
Ingrid Bispo et al.
Introduction: Choosing the treatment for kidney failure, whether dialysis or kidney conservative care, is challenging. Many adults may experience regret about this decision, leading to poor quality of life. This review ai...
Contiguous Gene Deletion Involving COL4A1 and COL4A2 in a Patient with Thin Basement Membrane Nephropathy: A Case Report [0.03%]
COL4A1和COL4A2基因串联缺失与薄基底膜肾病的关系：病例报告
Marc Henein,Felicia Russo,Chantal Bernard et al.
Marc Henein et al.
Introduction: Type IV collagen trimers are major structural components of the kidney glomerulus and tubules. Several loss-of-function COL4A1 and COL4A2 variants have been reported to cause cerebral small vessel disease. H...
Case Reports
Nephron. 2025 Nov 21:1-15. DOI:10.1159/000549595 2025
Vetle Saastad,Ludvig Balteskard Rinde,Inger Therese Enoksen et al.
Vetle Saastad et al.
Background There are considerable sex and gender differences in the epidemiology of chronic kidney disease (CKD), with CKD stage 3, defined as a glomerular filtration rate (GFR) below 60, being more prevalent in women. This raises questions...
Review
Nephron. 2025 Nov 18:1-8. DOI:10.1159/000549078 2025