The role of long non-coding RNAs and circular RNAs in immune evasion of influenza A virus: recent advances [0.03%]
流感病毒免疫逃逸中长非编码RNA和环状RNA的作用：最新研究进展
Yanghua Ju,Yanchun Li,Chenxu Zhou et al.
Yanghua Ju et al.
The capacity of influenza A virus (IAV) to circumvent immune defenses in hosts renders it a persistent major peril to worldwide public health. Investigations conducted lately underscore the vital functions played by circular RNAs (circRNAs)...
Increased abundance of actinobacteria and upregulation of primary bile acid biosynthesis in diabetic foot ulcers [0.03%]
糖尿病足溃疡中放线菌的富集及初级胆酸生物合成的上调
Mi Zhou,Han Zhang,Rui Zhang et al.
Mi Zhou et al.
Background: Vascular microbial imbalance may disrupt homeostasis and impair wound healing by triggering local and systemic inflammation. Diabetic foot (DF), a severe complication of diabetes, is frequently associated with...
Direct detection of Gram-negative bacilli and extended-spectrum β-lactamase producers in positive blood culture specimens using MALDI-TOF MS [0.03%]
采用基质辅助激光解析电离飞行时间质谱技术对阳性血培养中的肠杆菌目细菌及超广谱β内酰胺酶产生产物进行直接鉴定
Kosuke Kosai,Yasuhide Kawamoto,Fujiko Mitsumoto-Kaseida et al.
Kosuke Kosai et al.
Bloodstream infections caused by antimicrobial-resistant Gram-negative bacilli are often difficult to treat. Here, we investigated the performance of a workflow for direct detection of Gram-negative bacilli and extended-spectrum β-lactamas...
Recirculating glass pipettes constitute a high risk when working with freshly isolated immune cells - the presence of bacterial pyrogenic material [0.03%]
回收式玻璃吸管在处理刚分离的免疫细胞时存在高风险-含有细菌热原物质
Srinivas Akula,Sandra Lara,Anna-Karin Olsson et al.
Srinivas Akula et al.
A number of immune cells are highly sensitive to pyrogenic substances such as bacterial lipopolysaccharides (LPS). It is therefore crucial to ensure that all material coming in contact with these cells are pyrogen free. We here present a co...
Overcoming antifungal resistance in Candida albicans via RNA interference: a therapeutic perspective [0.03%]
利用RNA干扰克服白色念珠菌的抗真菌耐药性：治疗学观点
Akshay Kisan Mundhe,Reena Rajkumari
Akshay Kisan Mundhe
Candida albicans remains a significant cause of nosocomial infections, with increasing antifungal resistance posing a global health challenge. Current therapies, including azoles, echinocandins, and polyenes, are increasingly limited by evo...
Editorial: Innovative vaccine strategies for enhanced flavivirus immunization [0.03%]
评论：改进黄病毒免疫的创新疫苗策略
Srinivasa Reddy Bonam,Nitin K Saksena,Pedro A Reche
Srinivasa Reddy Bonam
Sublingual immunization with E2-CD154 protein and the STING agonist c-di-AMP confers protection against classical swine fever virus in pigs [0.03%]
E2-CD154蛋白和STING激动剂c-di-AMP的舌下免疫对猪经典猪瘟病毒的防护效果
Sara Puente-Marin,Talía Sardina-González,Liani Coronado et al.
Sara Puente-Marin et al.
Introduction: Subunit vaccines represent a safer alternative to live attenuated formulations. However, they often require potent adjuvants and delivery systems to elicit robust immunity, particularly against highly contag...
Harnessing phages to tackle antimicrobial resistance: a Saudi Arabian perspective [0.03%]
噬菌体在应对抗生素耐药性问题中的作用——沙特阿拉伯的视角
Alhassan Alrafaie
Alhassan Alrafaie
The worldwide antimicrobial resistance (AMR) threat continues to grow, causing an estimate of 4.71 million deaths during 2021. Scientists predict it could lead to 10 million deaths each year by 2050 unless effective solutions are developed....
Hospital-associated MRSA genotypes causing complicated community-onset skin and musculoskeletal infections [0.03%]
医院相关型MRSA所致复杂性社区获得性皮肤及骨关节感染的基因分型研究
Stefânia Bazanelli Prebianchi,Ingrid Nayara Marcelino Santos,Isabelle Caroline Frois Brasil Tannus et al.
Stefânia Bazanelli Prebianchi et al.
Objectives: To assess clinical and epidemiological characteristics, and phenotypic and genomic risk factors associated with severity and death in complicated community-onset skin, soft tissue, and musculoskeletal infectio...
Bone and joint tuberculosis: clinical manifestation, diagnostic techniques and drug resistance analysis [0.03%]
骨和关节结核的临床表现、诊断技术及耐药分析
Yingying Yuan,Pengxiang Li,Xiangjie Qiu et al.
Yingying Yuan et al.
Objectives: Clinical data on bone and joint tuberculosis (BJTB) in developing countries remain limited. This study aims to investigate the clinical, epidemiological, and drug-resistance characteristics of BJTB patients in...