TNFα Drives Disease-Specific Chemokine Networks and Orbital Tissue Remodeling in a Preclinical Model of Thyroid Eye Disease [0.03%]
肿瘤坏死因子α在甲状腺眼病的前临床模型中驱动疾病特异性细胞因子网络和眼眶组织重塑
Anke Daser,Anne Gulbins,Mareike Horstmann et al.
Anke Daser et al.
Background: Thyroid eye disease (TED) is characterized by orbital inflammation, fibroblast activation, and pathological tissue remodeling. While autoimmunity to the thyrotropin receptor (TSHR) initiates disease, the contr...
Management of Endocrine Emergencies: Joint Consensus Statement for Management of Myxoedema Coma [0.03%]
内分泌急诊处理共识 statement-myxoedema昏迷管理
Peter Taylor,Fraser Gibb,Marco Medici et al.
Peter Taylor et al.
Myxoedema coma is a rare, life-threatening endocrine emergency resulting from severe hypothyroidism, most commonly affecting older adults. It is characterised by altered mental status, hypothermia, and multiorgan dysfunction, with a high mo...
2026 ETA guideline on interference in immunoassay measurements used in assessment of thyroid function [0.03%]
2026年甲状腺功能评估用免疫分析干扰指南(ETA指南)
Irene Campi,Ulla Feldt-Rasmussen,Damien Gruson et al.
Irene Campi et al.
Although measurement of thyroid hormones (TH), TSH and thyroid autoantibodies is usually straightforward, erroneous results are occasionally generated, raising the possibility of incorrect or delayed diagnoses, unwarranted investigations an...
Laura Croce,Isabella Chiardi,Silvia Anna Marchiselli Dell&#x;Innocenti et al.
Laura Croce et al.
Obesity and thyroid disorders are highly prevalent conditions with complex, bidirectional interactions. Thyroid hormones, particularly triiodothyronine, regulate energy expenditure, thermogenesis, and lipid metabolism, while excess adiposit...
Triiodothyroacetic acid exerts tissue-specific thyromimetic effects without tachycardia and hyperthermia in male mice [0.03%]
三碘甲氨嘧啶在雄性小鼠中产生组织特异性的促甲状腺作用而不引起心动过速和发热
Beate Herrmann,Lena Adam,Rebecca Oelkrug et al.
Beate Herrmann et al.
Objective: Thyroid hormones regulate cardiovascular functions and energy homeostasis including thermogenesis through binding to nuclear thyroid hormone receptors. The thyroid hormone analogue 3,3',5-triiodothyroacetic aci...
Single-cell RNA sequencing: a powerful tool to study heterogeneity in papillary and anaplastic thyroid carcinoma [0.03%]
单细胞RNA测序：研究乳头状和未分化型甲状腺癌异质性的有力工具
Vicente Rodrigues Marczyk,Jennifer Rui Wang
Vicente Rodrigues Marczyk
Thyroid cancers are a complex ecosystem comprising cancer cells along with stromal and immune cells in the tumor microenvironment. In recent years, single-cell RNA sequencing has transformed our understanding of tumor heterogeneity, enablin...
Estimation of the delay for resumption of breastfeeding after 131-iodine therapy by milk radioactivity measurement [0.03%]
通过测量乳汁放射性来估计131-I治疗后恢复母乳喂养的时间延误
Sarah Chaib,Solène Castellnou,Tassadit Keniza et al.
Sarah Chaib et al.
Guidelines recommend stopping breastfeeding before radioactive iodine (131I) therapy, yet the optimal timing for safe resumption remains unclear. We report a detailed dosimetric case study of a 29-year-old woman treated with 3700 MBq 131I f...
Optimizing Frozen Section Sampling for Thyroid Follicular Neoplasms through Intraoperative Ultrasound Guidance [0.03%]
超声引导优化甲状腺滤泡性肿瘤冰冻切片取材
Bo Yu,Xin Li,Fang Mei et al.
Bo Yu et al.
Objective: To investigate the clinical value of intraoperative high-frequency ultrasound in assessing the capsular continuity of thyroid follicular neoplasms and to evaluate its feasibility in guiding optimal frozen secti...
The Effect of Iodinated Contrast Media on Thyroid (Dys)function in Children [0.03%]
碘化对比剂对儿童甲状腺功能影响的研究进展
Freya Vancauwenbergh,Brigitte Decallonne,Anne Maria Rochtus
Freya Vancauwenbergh
Background: Excess iodine from iodinated contrast media (ICM) can lead to thyroid dysfunction. Children, especially neonates and premature infants, may be more vulnerable due to their immature thyroid physiology. ...
Associations of sphingosine-1-phosphate with thyroid function and structure: A cross-sectional population-based study [0.03%]
鞘氨醇-1-磷酸与甲状腺功能和结构的相关性：一项基于人口的横断面研究
Lisa Bähr,Stefan Gross,Marcus Dörr et al.
Lisa Bähr et al.
Objective: Sphingosine-1-phosphate (S1P) is a versatile immunomodulatory lipid mediator that affects both immune and cardiovascular health. S1P has been linked to thyroid health, for example by affecting inflammatory reac...