Karol Gawalski,Weronika Przybyszewska,Jaromir Hunia et al.
Karol Gawalski et al.
Messenger ribonucleic acid (mRNA) technology is a promising platform for cancer immunotherapy. Unlike traditional vaccines that prevent infectious diseases, mRNA's role in oncology is to stimulate or enhance the immune response against tumo...
Rectal spacer use and overall long-term healthcare costs: payer perspective [0.03%]
直肠隔舱器使用与长期整体医疗费用：支付方视角
James B Yu,Ryoko Sato,Michael R Folkert et al.
James B Yu et al.
Introduction: Rectal spacers (RS), when used in prostate cancer (PCa) patients treated with radiotherapy (RT), reduce radiation dose to the rectum. While RS incur additional upfront cost, they may result in long-term cost...
Analysis of the safety and efficacy of PD-1/PD-L1 inhibitors combined with chemotherapy in the treatment of locally advanced resectable esophageal squamous cell carcinoma: a systematic review and meta-analysis based on four randomized controlled trials [0.03%]
PD-1/PD-L1抑制剂联合化疗治疗局部晚期可切除食管鳞癌的安全性及有效性的系统评价和meta分析（基于4项随机对照试验）
Tao Luo,Hao Yang,Xingqiang Ran et al.
Tao Luo et al.
Background: Esophageal cancer is a leading type of cancer globally. Most patients diagnosed with esophageal cancer present at a locally advanced stage, for which the standard treatment paradigm involves a multimodal appro...
Case Report: Unlocking opportunities in HER2-targeted antibody-drug conjugates for bulky leptomeningeal metastatic breast cancer [0.03%]
病例报告：针对肿瘤负荷较大脑膜转移性乳腺癌的HER2靶向抗体药物偶联物治疗机遇解锁
Alessandro Leal,Douglas Kondziolka,Donato Pacione et al.
Alessandro Leal et al.
Leptomeningeal carcinomatosis (LC) is a severe complication of metastatic breast cancer (mBC), with rising incidence. The prognosis for patients with LC has been poor, with a median overall survival of approximately four months. However, re...
Epstein-Barr virus-driven molecular pathogenesis of primary pulmonary lymphoepithelial carcinoma [0.03%]
EB病毒所致原发性肺淋巴上皮瘤样癌的分子发病机制研究
Mingyuan Xie,Dong Yao,Liping Lei et al.
Mingyuan Xie et al.
Primary Pulmonary Lymphoepithelial Carcinoma (PLEC) is a rare subtype of non-small cell lung cancer (NSCLC) that exhibits a strong association with Epstein-Barr virus (EBV) infection and shows distinctive geographic and ethnic predilections...
Multidisciplinary strategies to reduce radiotherapy-induced cardiotoxicity in breast cancer: surgical and technological innovations [0.03%]
乳腺癌放射治疗引起的心脏毒性的多学科防治策略：手术及技术新进展
Kai Lu,Zhenhua Sun,Yide Yi
Kai Lu
Radiotherapy remains essential in breast cancer management, yet its long-term cardiotoxicity, driven primarily by radiation-induced myocardial fibrosis, threatens survivorship, particularly in left-sided tumors. Surgical refinements, includ...
Deep learning radiomics nomogram predicts lymph node metastasis in laryngeal squamous cell carcinoma [0.03%]
基于深度学习的影像组学列线图预测喉鳞癌淋巴结转移
Yun Liang,Min He,Wenqing Chen et al.
Yun Liang et al.
Background: Lymph node metastases (LNM) in laryngeal squamous cell carcinoma (LSCC) has been associated with lower survival, but current imaging methods, such as computed tomography (CT), have limited capabilities to iden...
Quality of life in patients with pan-cancer undergoing concurrent chemoradiotherapy: a bibliometric analysis (1995-2024) [0.03%]
泛癌患者同步放化疗的生活质量：1995-2024年文献计量分析
Ao Shen,Pan Fan,Dingrong Fan et al.
Ao Shen et al.
Background: Chemoradiotherapy is a therapeutic approach that prolongs survival but may simultaneously negatively affect the quality of life (QOL) of cancer patients. Current research on quality of life (QOL) in pan-cancer...
Comprehensive single-cell sequencing reveals the tumor microenvironment and tumor-specific characteristics in trachea squamous cell carcinoma [0.03%]
综合单细胞测序揭示了气管鳞状细胞癌的肿瘤微环境及肿瘤特异性特征
Hongwu Wang,Hongli Li,Heng Zou et al.
Hongwu Wang et al.
Trachea squamous cell carcinoma (TSCC) is a subtype of lung cancer. A thorough investigation of the tumor microenvironment of TSCC is crucial for the development of cancer therapeutics and predicting clinical responses. In this study, we ut...
Expression of immune checkpoints (IDO and PD-L1) in oral tongue cancer patients: a 10-year retrospective cohort study in Pakistan [0.03%]
巴基斯坦舌癌患者免疫检查点（IDO和PD-L1）的表达：一项为期10年的回顾队列研究
Merium Fatima,Shaarif Bashir,Syed Atif Raza et al.
Merium Fatima et al.
Background: Tongue squamous cell carcinoma (TSCC) is a significant global health issue with high incidence and mortality rates. Current treatments involve surgery, radiotherapy, and chemotherapy; however, prognosis remain...