Nanoparticle albumin-bound paclitaxel -induced severe interstitial lung disease in a gastric cancer patient: a case report [0.03%]
纳米白蛋白结合型紫杉醇致胃癌患者严重间质性肺病1例报告
Baosheng Liu,Kaihui Wei,Jianru Dong et al.
Baosheng Liu et al.
Background: Nanoparticle albumin-bound paclitaxel (nab-PTX) is a novel formulation that combines paclitaxel with human serum albumin via nanotechnology. Without the need for solubilizers, it allows for higher safe doses, ...
Retrospective analysis of nanoparticle albumin-bound paclitaxel combined with toripalimab and platinum as first-line treatment for Chinese patients with recurrent or metastatic head and neck cancer [0.03%]
纳米白蛋白颗粒结合紫杉醇联合托里帕利玛和铂作为中国复发或转移性头颈部癌症患者一线治疗的回顾性分析
Jinlan Li,Rui Zhong,Shuo Yang et al.
Jinlan Li et al.
Objective: To evaluate the clinical efficacy and safety of toripalimab combined with albumin-bound paclitaxel and cisplatin/carboplatin as first-line treatment for recurrent or metastatic head and neck squamous cell carci...
Case Report: Complete remission of thymic carcinoma using dose-dense chemotherapy [0.03%]
病例报告：使用密集疗程化疗使胸腺癌完全缓解
Mae Shu,Tieying Hou,Stacy M Rissing et al.
Mae Shu et al.
Thymic epithelial tumors, including thymoma and thymic carcinoma, are rare malignancies of the mediastinum, often associated with poor long-term outcomes in advanced stages. Surgical resection and platinum-based chemotherapy have been the c...
Penile involvement associated with renal pelvic squamous cell carcinoma: a case report and mechanistic considerations [0.03%]
与肾盂鳞状细胞癌相关的阴茎受累：一例报告及发病机制考虑因素
Kotaro Masaki,Takuya Tsujino,Hiroyuki Okada et al.
Kotaro Masaki et al.
Background: Squamous cell carcinoma (SCC) of the renal pelvis is an uncommon malignancy, accounting for less than 1% of upper urinary tract tumors. Penile metastasis from renal pelvic SCC has not been documented. ...
Study on the mechanism of 18β-glycyrrhetinic acid inhibiting the proliferation of renal cancer cells by inducing autophagy through the miR-27a-5p/LC3 axis [0.03%]
通过miR-27a-5p/LC3轴诱导自噬抑制肾癌细胞增殖的甘草酸酯作用机制研究
Shumin Jia,Lei Zhang,Yahong Li et al.
Shumin Jia et al.
Background: Renal carcinoma is a common, aggressive urinary tract malignancy with notable clinical challenges such as severe treatment toxicity and poor patient outcomes; 18β-glycyrrhetinic acid (18β-GA), an active comp...
Adoptive transfer of ILC2s reveals tumor homing in glioblastoma: a proof-of-concept study [0.03%]
关于胶质母细胞瘤ILC2s肿瘤归巢的过继转移：概念验证研究
Lei P Wang,Bidhan Bhandari,Sahar Emami Naeini et al.
Lei P Wang et al.
Introduction: Glioblastoma (GBM) is an aggressive brain tumor with limited treatment options and poor immune cell infiltration. Although cellular immunotherapies have transformed cancer treatment, they remain largely inef...
Efficacy of sacituzumab govitecan in triple-negative breast cancer with hepatic visceral crisis: a case report [0.03%]
靶向治疗肝转移三阴性乳腺癌1例报告 Sacituzumab govitecan 治疗肝脏受累三阴性乳腺癌的疗效观察
Jiaqi Ye,Jiaang Ye,Huijuan He et al.
Jiaqi Ye et al.
Triple-negative breast cancer (TNBC) is recognized as the most aggressive molecular subtype of breast cancer (BC). The liver is a common site of distant metastasis in BC, and hepatic involvement is associated with accelerated therapeutic re...
A systematic characterization of amino acid metabolism-related genes reveals molecular subtypes and a prognostic signature in bladder cancer [0.03%]
系统表征氨基酸代谢相关基因可揭示膀胱癌的分子亚型和预后标志物
Junrui He,Xu Liu,Shirui Li et al.
Junrui He et al.
Background: Amino acid metabolism is integral to tumor proliferation, redox control, and immune regulation. Yet, studies in bladder cancer have largely centered on single amino acids, leaving the broader metabolic gene ne...
Global, regional and national burden of colon and rectum cancer attributable to high fasting plasma glucose: a systematic analysis for the Global Burden of Disease Study 2021 [0.03%]
基于全球疾病负担研究2021的全球、区域和国家层面空腹血糖水平升高归因结直肠癌疾病负担系统分析
Ke Lu,Gang Xu
Ke Lu
Background: Colorectal cancer (CRC), the third most common malignant cancer globally, imposes a substantial public health burden. Emerging evidence has highlighted hyperglycemia as an independent risk factor for CRC. Esti...
Case Report: Furmonertinib dose escalation in heavily pretreated EGFR-mutant lung adenocarcinoma with diffuse brain metastases [0.03%]
富马喹替尼剂量递增治疗EGFR突变肺腺癌伴广泛脑转移的病例报告
Zian Jin,Changhong Dong,Kaiyuan Hui et al.
Zian Jin et al.
Furmonertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, has demonstrated systemic and central nervous system (CNS) antitumor activity in patients with EGFR-mutant non-small cell lung cancer (NSCL...