Proton stereotactic centralized ablative radiation therapy for treating bulky tumor: a treatment plan study [0.03%]
大体积肿瘤质子立体定向集中消融放射治疗的计划研究
Tengxiang Li,Xinsen Yao,Ruimin He et al.
Tengxiang Li et al.
Objective: Stereotactic centralized/core ablative radiation therapy (SCART) is a novel radiotherapy approach. This study investigates the potential benefits of proton-based SCART (pSCART) by leveraging the dosimetric adva...
Translating the multifaceted use of liquid biopsy to management of early disease in pancreatic adenocarcinoma [0.03%]
液体活检在胰腺导管腺癌早期诊断和管理中的应用展望
Madison Cox,Dominic Vitello,Akhil Chawla
Madison Cox
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related mortality, primarily due to late stage at diagnosis. This review examines the multifaceted applications of liquid biopsy and circulating tumor DNA (ctDNA) analysis...
Establishment and validation of a prognostic nomogram for extra-gastrointestinal stromal tumors [0.03%]
胃肠道间质瘤以外的细胞肉瘤预后预测列线图的建立和验证
Guohua Jia,Xiangpan Li
Guohua Jia
Background: Extra-gastrointestinal stromal tumor (EGIST) is a rare subtype of gastrointestinal stromal tumor, with limited information on its clinical characteristics and prognostic factors. This study aims to identify th...
The immune cell dynamics in the peripheral blood of cHL patients receiving anti-PD1 treatment [0.03%]
接受抗PD1治疗的cHL患者外周血免疫细胞动态变化研究
Vanessa Cristaldi,Lodovico Terzi di Bergamo,Lucrezia Patruno et al.
Vanessa Cristaldi et al.
Checkpoint blockade therapy (CBT) involving anti-PD1 antibodies represents the standard approach for cHL patients who do not respond to second-line therapy. Nonetheless, only 20% of relapsed/refractory (R/R) cHL patients treated with CBT ac...
Prognosis of palliative treatment for primary tracheal carcinoma: a two-center retrospective study [0.03%]
原发性气管癌姑息治疗预后分析：多中心回顾性研究
Qinyan Hong,Jun Teng,Yi Luo et al.
Qinyan Hong et al.
Introduction: More than half of patients with tracheal carcinoma (TC) do not receive radical treatment, but the clinical characteristics, palliative treatment options, and prognosis of this group remain unclear. ...
Polysialic acid is upregulated on activated immune cells and negatively regulates anticancer immune activity [0.03%]
多唾液酸在活化免疫细胞中上调并负向调控抗肿瘤免疫活性
Olivia Drummond-Guy,John Daly,Angeline Wu et al.
Olivia Drummond-Guy et al.
Suppression of anticancer immune function is a key driver of tumorigenesis. Identifying molecular pathways that inhibit anticancer immunity is critical for developing novel immunotherapeutics. One such molecule that has recently been identi...
Development of a mitochondria-related gene signature for prognostic assessment in diffuse large B cell lymphoma [0.03%]
弥漫性大B细胞淋巴瘤预后评估的线粒体相关基因特征的建立
Fujue Wang,Yu Gao,Yue Chen et al.
Fujue Wang et al.
Background: Mitochondria-related genes (MitoRGs) play a critical role in the pathogenesis of various cancer types. This study aims to develop a novel prognostic model based on a MitoRGs signature for patients with diffuse...
A retrospective study of imaging characteristics of mucinous tubular and spindle cell carcinoma in the kidney [0.03%]
肾黏液性管周梭形细胞癌的影像学特征回顾性分析
Hong Wang,Xiaoyan Peng,Lutong Li et al.
Hong Wang et al.
Purpose: To strengthen the recognition of mucinous tubular and spindle cell carcinomas of the kidney (MTSCC) by analyzing ultrasound and computed tomography findings. ...
Prognostic factors in locally advanced oesophageal squamous cell carcinoma: a clinical and radiomic analysis of neoadjuvant immunochemotherapy before surgery [0.03%]
新辅助免疫化疗术前局部晚期食管鳞癌的临床和影像组学预后因素分析
Yan Zhu,Zhenzhong Zhang,Shuangqing Chen et al.
Yan Zhu et al.
Background: The treatment of locally advanced oesophageal squamous cell carcinoma (LAESCC) without distant metastasis remains a subject of debate. Neoadjuvant immunochemotherapy (NIC) combined with surgery is the preferre...
The role and mechanism of selenium in the prevention and progression of hepatocellular carcinoma [0.03%]
硒在肝细胞癌预防和进展中的作用和机制研究
Qinying Luo,Xiaofang Bai,Xiaojiao Li et al.
Qinying Luo et al.
Hepatocellular carcinoma (HCC) represents the most prevalent form of liver cancer. Despite notable advancements in therapeutic strategies, HCC continues to pose significant public health challenges due to its rising incidence and high morta...