PSMD11 and PSMD14 may serve as novel biomarkers for the prognosis of pancreatic ductal adenocarcinoma [0.03%]
PSMD11和PSMD14可能是预测胰腺导管腺癌预后的新型生物标志物
Yan-Hui Yang,Zhe-Hua Xing,Hao Wang et al.
Yan-Hui Yang et al.
Background: The ubiquitin proteasome system is involved in the regulation of cellular gene transcription and cellular receptor function through the degradation of proteins, thus affecting tumorigenesis and development. In...
Identifying new therapeutics for focused ultrasound-enhanced drug delivery in the management of glioblastoma [0.03%]
用于增强聚焦超声药物递送管理胶质母细胞瘤的新疗法的识别
Ryan Holman,Nathan McDannold
Ryan Holman
Glioblastoma, a grade IV astrocytoma, typically has a poor prognosis, with most patients succumbing within eighteen months of diagnosis and few experiencing long-term survival. Focused ultrasound, an emerging localized therapy, has shown pr...
Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner [0.03%]
α-突触核蛋白敲除以性别依赖的方式损害黑色素瘤TG3小鼠模型的发病并改变DNA损伤修复反应
Moriah R Arnold,Suzie Chen,Vivek K Unni
Moriah R Arnold
Introduction: Strong evidence suggests links between Parkinson's Disease (PD) and melanoma, as studies have found that people with PD are at an increased risk of developing melanoma and those with melanoma are at increase...
Durable response to Olaparib in EGFR and somatic BRCA2-mutated lung adenocarcinoma with leptomeningeal metastases: a case report [0.03%]
奥拉帕利治疗EGFR突变和体细胞BRCA2突变肺癌伴脑膜转移的病例报道
Fang-Fang Hou,Li-Rong Liu,Wen-Jie Zhao et al.
Fang-Fang Hou et al.
Mutations in breast cancer susceptibility genes 1/2 (BRCA1/2) are strongly associated with a significantly higher risk of numerous cancers, including ovarian, breast, prostate, and pancreatic cancer. PARP inhibitors have been approved for t...
Surveillance of de novo head and neck cancer in liver transplant recipients allows an early diagnosis: a retrospective analysis of a surveillance program [0.03%]
对肝移植受者的头颈部新发癌症的监测可实现早期诊断：一项回顾性分析研究
Ivan Zambrano,Juan Alcalde,Mercedes Iñarrairaegui et al.
Ivan Zambrano et al.
Introduction: De novo head and neck cancer is a common and severe complication than can occur after liver transplantation. However, it is unclear whether surveillance can help detect and prevent this type of cancer in liv...
Development and validation of nomogram models for predicting immune-related adverse events in recurrent and metastatic nasopharyngeal carcinoma patients treated with PD-L1 inhibitors [0.03%]
预测PD-L1抑制剂治疗复发及转移性鼻咽癌患者免疫相关不良事件的列线图模型的建立和验证
Mengyuan Liu,Zheran Liu,Shuangshuang He et al.
Mengyuan Liu et al.
Objective: To predict the incidence of immune-related Adverse Events (irAEs) in patients with recurrent or metastatic Nasopharyngeal Carcinoma (NPC) treated with Programmed Death-Ligand 1 (PD-L1) inhibitors, this study de...
Case Report: Differentiating hepatic desmoplastic small round cell tumor from hydatidosis in a school-aged boy: the role of contrast-enhanced and interventional ultrasound [0.03%]
个案报告：对比增强及介入超声在区分学龄儿童肝包虫病与间叶性小圆细胞癌中的应用价值
Zehui Gou,Hualin Yan,Boyang Yu et al.
Zehui Gou et al.
Background: Desmoplastic small round cell tumor (DSRCT) is a rare and highly aggressive malignant neoplasm, typically associated with poor prognosis. It predominantly affects adolescents and young males, with a lower inci...
Immuno-inflammatory mechanisms in cardio-oncology: new hopes for immunotargeted therapies [0.03%]
心脏肿瘤免疫炎症机制的新希望——免疫靶向治疗
Meiqi Miao,Xinxin Liu,Han Zhang et al.
Meiqi Miao et al.
Cardio-oncology is an emerging interdisciplinary field concerned with cancer treatment-related cardiovascular toxicities (CTR-CVT) and concomitant cardiovascular diseases (CVD) in patients with cancer. Inflammation and immune system dysregu...
Editorial: Breast cancer imaging: clinical translation of novel methods [0.03%]
述评：乳腺癌影像诊断：新型方法的临床转化
Sai Man Cheung,Simone Palma,Luca Nicosia et al.
Sai Man Cheung et al.
The evolving landscape of genetic biomarkers for immunotherapy in primary and metastatic breast cancer [0.03%]
原发性和转移性乳腺癌免疫治疗的遗传生物标志物的发展格局
Liang Jin,Zijian Yang,Wei Tang et al.
Liang Jin et al.
Background: Major advances have been achieved in the characterization of primary breast cancer genomic profiles. Limited information is available on the genomic profile of tumors originating from different metastatic loca...