Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy [0.03%]
安格特罗通过抑制PI3K/Akt/mTOR信号通路和激活自噬抑制软骨肉瘤细胞迁移和侵袭
Chun-Fei Wu,Li-Xin Ouyang,Wan-Hao Zhang et al.
Chun-Fei Wu et al.
Objective: Chondrosarcoma, a malignant bone tumor, exhibits a high incidence rate. This study employed network pharmacology and cell-based experiments to explore the molecular mechanisms by which andrographolide (Andro) s...
Association of the triglyceride-glucose index with immunotherapy efficacy and long-term prognosis in advanced Non-small cell lung cancer [0.03%]
甘油三酯-葡萄糖指数与晚期非小细胞肺癌免疫治疗疗效及长期预后的关联性分析
Lijie Ma,Wanling Zhu,Yulang Wang et al.
Lijie Ma et al.
Background: Non-small cell lung cancer (NSCLC), the most common subtype of primary lung cancer, represents a major component of the global cancer burden. Despite the availability of several immunotherapeutic and immune-co...
A global analysis of nasopharynx cancer burden attributable to occupational formaldehyde exposure [0.03%]
职业甲醛暴露所致鼻咽癌疾病负担的全球分析
Jian Li,Yongjing Lai,Anzhou Tang et al.
Jian Li et al.
Background: Occupational formaldehyde is a significant risk factor for nasopharynx cancer. This study aimed to analyze the burden of nasopharynx cancer attributable to occupational formaldehyde using data from the Global ...
A endometrial malignant tumor with yolk sac tumor component: a case report and literature review [0.03%]
含有卵黄囊肿瘤成分的子宫内膜恶性肿瘤一例报告及文献复习
Zicheng Cui,Yuping Shan,Huijun Chu et al.
Zicheng Cui et al.
Background: Primary endometrial yolk sac tumor (YST), as an extragonadal germ cell tumor, is an exceedingly rare malignancy characterized by high aggressiveness and poor prognosis. Currently, there is no standardized and ...
Reproductive outcomes of pregnancy after breast cancer: an updated systematic review and meta-analysis [0.03%]
乳腺癌后妊娠的生殖结局：一项更新的系统评价和meta分析研究
Qingya Song,Heting Mei,Wenping Lu et al.
Qingya Song et al.
Background: Reproductive outcomes following pregnancy in premenopausal women with breast cancer (BC) remain contentious, and few meta-analyses have adequately addressed these questions. This systematic review and meta-ana...
Safety analysis of omitting axillary lymph node dissection in early-stage breast cancer with 1-2 sentinel lymph nodes macro-metastases: a meta-analysis [0.03%]
前哨淋巴结宏转移的早期乳腺癌省略腋窝淋巴结清扫的安全性分析：一项系统综述和meta分析
Yu Chen,Xiaoming Zhang,Qingping Wu et al.
Yu Chen et al.
Background: Currently, the axillary management strategy of omitting axillary lymph node dissection (ALND) in early-stage breast cancer (BC) patients with cT1-2, clinically node-negative (cN0), and sentinel lymph node biop...
A case report on IDH-mutant astrocytoma, CNS WHO grade 4: multi-omic characterization of untreated clinical progression [0.03%]
一例IDH突变型四分子胶质瘤（WHO IV级）的多组学表征未治疗的临床进展(case report)
Xiaoqin Tang,Wei Wei,Yanyan Huang et al.
Xiaoqin Tang et al.
Background: The natural history of untreated IDH-mutant astrocytoma, CNS WHO grade 2, progressing to astrocytoma grade 4 remains poorly characterized. Met...
Ensemble machine learning models for predicting bone metastasis in bladder cancer [0.03%]
基于集合机器学习的膀胱癌骨转移预测模型
Zhan Jiang Yu,Xiang Da Xu,Xin Chang Zou et al.
Zhan Jiang Yu et al.
Background and purpose: The occurrence of bone metastasis (BM) in advanced bladder cancer (BC) often signifies a poor prognosis. Currently, the accurate prediction of BM in BC remains a challenge. This study develops pred...
Unveiling new insights: a comprehensive questionnaire-based single-center study of sebaceous nevus [0.03%]
揭开启新见解的序幕：一项基于问卷的单中心综合研究，探究皮脂腺痣病症
Jiamin Jin,Tao Dai,Lu An et al.
Jiamin Jin et al.
Introduction: Sebaceous nevus (SN) is a rare, benign, congenital tumor. There is limited information on its clinical features, familial influences, quality of life (QoL) impact, and treatment outcomes in Chinese patients....
Increased acid sphingomyelinase levels in saliva as oral mucositis severity predictors [0.03%]
唾液酸性鞘磷脂酶水平作为口腔黏膜炎严重程度预测因子的作用研究
Elsa Beatriz Monroy Ordonez,Tanja Sprave,Andreas R Thomsen et al.
Elsa Beatriz Monroy Ordonez et al.
Introduction: Radiotherapy (RT) plays a central role in multidisciplinary treatment approaches in cancer therapy, particularly as an effective primary treatment modality for patients with head and neck cancer (HNC). One o...