Multiple drug resistance caused by germline mutation of exon 27 of BRCA2 gene in triple-negative breast cancer: a case report and literature review [0.03%]
BRCA2基因外显子27生殖细胞突变所致三阴性乳腺癌多药耐药的病例报告及文献复习
Yuting Li,Guojie Xu,Liling Zhang et al.
Yuting Li et al.
BRCA genes, including BRCA1 and BRCA2, are tumor suppressor genes that play a crucial role in the HRR pathway for double-strand DNA breaks. Mutations in these genes lead to the loss of function of their respective proteins, resulting in HRD...
Xiao-Qing Tan,Ai-Ying Guo,Li-Fei Zheng et al.
Xiao-Qing Tan et al.
Ovarian cancer (OC) is the leading cause of cancer-related death among women, presenting a significant threat to their lives and health. Early-stage OC often lacks distinctive clinical symptoms, leading to most patients being diagnosed at a...
Lan Liu,Xiaowu Zhong,Yue Zhong et al.
Lan Liu et al.
Oral squamous cell carcinoma is among the most prevalent tumours of the oral and maxillofacial region. The initial symptoms are typically minor and may remain misdiagnosed until the disease advances, resulting in a significantly reduced fiv...
Hippo/YAP signaling pathway in colorectal cancer: regulatory mechanisms and potential drug exploration [0.03%]
斑马鱼结直肠癌中Hippo/YAP信号通路的调控机制及潜在药物探索
Lingqiu Zhang,Fan Zhang,Haimei Liang et al.
Lingqiu Zhang et al.
Objective: Colorectal cancer (CRC) remains a leading cause of cancer-related morbidity and mortality worldwide. The Hippo signaling pathway, particularly its downstream effector Yes-associated protein (YAP), has been iden...
Machine learning-based radiomics for differentiating lung cancer subtypes in brain metastases using CE-T1WI [0.03%]
基于机器学习的影像组学在CE-T1WI脑转移瘤中鉴别肺癌亚型中的应用
Xueming Xia,Wei Du,Qiheng Gou
Xueming Xia
Objectives: The purpose of this research was to create and validate radiomic models based on machine learning that can effectively discriminate between primary non-small cell lung cancer (NSCLC) and small cell lung cancer...
A nomogram for predicting overall survival in patients with muscle-invasive bladder cancer undergoing radical cystectomy: a retrospective cohort study [0.03%]
一项回顾性队列研究：用于预测膀胱切除术治疗肌层浸润性膀胱癌患者总生存率的诺模图
Haiming Huang,Han Hao,Jialin Du et al.
Haiming Huang et al.
Background and aims: Radical cystectomy (RC) remains the standard treatment for localized and regionally muscle-invasive bladder cancer (MIBC). However, only half of patients with MIBC survive more than 5 years after RC. ...
Scientometric analysis of lipid metabolism in macrophage polarization: 2013-2023 [0.03%]
2013-2023年巨噬细胞极化脂质代谢的科学计量分析
Chenxiao Ye,Xiaosong Ru,Yong Guo
Chenxiao Ye
Introduction: Macrophage polarization plays a crucial role in the development of various diseases. Simultaneously, macrophage polarization is intimately related to lipid metabolism. To assess the emerging trend of lipid m...
DynTransNet: Dynamic Transformer Network with multi-scale attention for liver cancer segmentation [0.03%]
基于多尺度注意力的动态变换网络在肝癌分割中的应用
Siming Zheng,A S M Sharifuzzaman Sagar,Yu Chen et al.
Siming Zheng et al.
Introduction: Hepatocellular carcinoma (HCC), a predominant subtype of liver cancer, remains Q7 a major contributor to global cancer mortality. Accurate delineation of liver tumors in CT and MRI scans is critical for trea...
Rare manifestations of pediatric chronic myeloid leukemia: a case report on priapism and a literature Review [0.03%]
儿童慢性髓系白血病罕见表现1例及文献复习
Rawan Budair,Laith Baqain,Rawad Rihani
Rawan Budair
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by uncontrolled myeloid cell proliferation and is primarily caused by a reciprocal chromosomal translocation [t(9;22)(q34;q11.2)]. Typical manifestations of CML i...
Case Report: Malignant transformation of ganglioneuroma in the rectovaginal septum to malignant peripheral nerve sheath tumor based on neurofibromas [0.03%]
个例报道：盆隔腔神经节神经瘤恶性转化为基础为神经纤维瘤的恶性外周神经鞘膜肿瘤
Xiaoxiao Xi,Hui Cheng,Shanyu Huang et al.
Xiaoxiao Xi et al.
Malignant peripheral nerve sheath tumor (MPNST) is a type of soft tissue sarcoma that commonly occurs in the trunk, limbs, and head and neck regions, but rarely in the pelvic area. Nearly half of MPNST cases are secondary to neurofibromatos...