Targeted and immunotherapy based on tissue of origin in carcinoma of unknown primary: a two-case report and literature review [0.03%]
组织来源导向的靶向及免疫治疗在未知原发灶癌中的应用：2例报告和文献回顾
Mei Wang,DongYue Yan,Wen Sun et al.
Mei Wang et al.
Background: Patients with carcinoma of unknown primary (CUP) generally have a poor prognosis due to the lack of effective treatment options resulting from unclear diagnosis. Determining the tumor type through tumor origin...
Risk-stratified surveillance after LEEP: a nomogram integrating HPV persistence, margin status, and clinical factors to predict CIN2+ recurrence [0.03%]
整合HPV持续感染、切缘状态和临床因素预测CIN2+复发的列线图用于LEEP术后分层管理
Haixia Shang,Xiaofeng Shi,Hongxin Yu et al.
Haixia Shang et al.
Background: Cervical intraepithelial neoplasia (CIN) recurrence after loop electrosurgical excision procedure (LEEP) remains a clinically consequential barrier to cervical cancer prevention, and risk stratification tools ...
Network connectome analysis of multi omics data identifies molecular markers of recurrence and grade progression in meningioma [0.03%]
基于多组学数据的脑膜瘤神经网络连接体分析鉴定出复发和分级进展的分子标志物
Jeong-An Gim,Hyun Jun Jo,Woo Keun Kwon et al.
Jeong-An Gim et al.
Background: Meningiomas are usually benign, but some behave aggressively with early recurrence. Histopathological grading alone often fails to predict outcomes. We developed a network connectome and clustering framework t...
Deceptive initial presentation of systemic DLBCL with CNS progression following Oligometabolic PET/CT: case report [0.03%]
以Oligometabolic PET/CT发现中枢神经系统受侵的DLBCL病例报告
Rui Yuan,Ya Yu,Qian Yang et al.
Rui Yuan et al.
We present a diagnostically challenging case of a 51-year-old woman with systemic diffuse large B-cell lymphoma (DLBCL) that progressed to secondary central nervous system (CNS) involvement. The initial presentation was notable for a whole-...
Disrupting PDGFRA-driven immune evasion in glioma: vaccine-based strategies on the horizon [0.03%]
针对胶质瘤PDGFRA驱动的免疫逃逸：基于疫苗的策略即将到来
Xialin Zhang,Xinwei Li,Ran Cui et al.
Xialin Zhang et al.
Gliomas, the most aggressive primary brain tumors, present a formidable challenge in neuro-oncology, characterized by infiltrative growth, high recurrence rates, and a profoundly immunosuppressive microenvironment that severely limits the e...
Correction: First-line treatment of camrelizumab combined with chemotherapy in advanced gastroenteropancreatic neuroendocrine carcinoma: study protocol for a prospective, multicenter, phase II study [0.03%]
替雷利珠单抗联合化疗一线治疗消化道神经内分泌癌的疗效和安全性：一项前瞻性、多中心Ⅱ期临床研究校稿版
Xiaofen Li,Qing Ma,Chen Chang et al.
Xiaofen Li et al.
[This corrects the article DOI: 10.3389/fonc.2022.958905.]. Keywords: camrelizumab; first line; gastroentero...
Published Erratum
Frontiers in oncology. 2026 Mar 2:16:1726750. DOI:10.3389/fonc.2026.1726750 2026
Building a framework for adolescent and young adult transition of care for patients with neurofibromatosis type 1 and neurofibromatosis type 2-related schwannomatosis syndromes [0.03%]
构建I型和II型神经纤维瘤病相关施万细胞瘤综合征的青少年及成年早期患者医疗过渡框架
Daniel Schwartzbaum,Christine Dinh,Nicholas A Borja et al.
Daniel Schwartzbaum et al.
Neurofibromatosis type 1 (NF1) and Neurofibromatosis Type 2-Related Schwannomatosis (NF2-SWN) are the two most common genetic disorders that present with Central nervous system(CNS) tumors. Patients with NF1 and NF2-SWN typically present in...
MiR-19b-3p facilitates colorectal cancer metastasis by mediating the crosstalk between tumor-associated endothelial cells and malignant cells [0.03%]
微RNA-19b-3p通过介导肿瘤相关内皮细胞与恶性细胞之间的相互作用促进结直肠癌的转移
Yixin Cao,Jia Zhang,Xinyu Kai et al.
Yixin Cao et al.
Background: The crosstalk between tumor cells and stromal components in the tumor microenvironment critically influences colorectal cancer (CRC) progression and metastasis. The role of tumor-associated endothelial cells (...
Prostatectomy versus definitive radiation for localized prostate cancer: revisiting the debate at a tertiary cancer center [0.03%]
前列腺癌根治术与放疗的疗效对比——在一家三级肿瘤医疗机构重新审视该话题
Ramiz Abu-Hijlih,Abdulla Alzibdeh,Haneen Abaza et al.
Ramiz Abu-Hijlih et al.
Background: Surgery and radiotherapy are the main treatments for localized prostate cancer. Although many retrospective studies have compared their efficacy, evidence from the Middle East and North Africa (MENA) region is...
The protease inhibitor gabexate mesylate targets Raf kinase inhibitor protein and reverses epithelial-mesenchymal transition in triple-negative breast cancer cells [0.03%]
蛋白酶抑制剂甲磺酸加贝酯通过靶向作用于Raf激酶抑制蛋白逆转三阴性乳腺癌上皮间质转化效应
Marzia Deserti,Simone Sabbioni,Francesca Poli et al.
Marzia Deserti et al.
The prognosis of triple-negative breast cancer (TNBC) still remains poor, mainly due to the occurrence of early metastases and the lack of effective treatments. The Raf kinase inhibitor protein (RKIP) is a tumor metastasis suppressor freque...