GART promotes the proliferation and migration of human non-small cell lung cancer cell lines A549 and H1299 by targeting PAICS-Akt-β-catenin pathway [0.03%]
GART通过靶向PAICS-Akt-β-catenin途径促进人非小细胞肺癌A549和H1299细胞系的增殖和迁移
Zhuo Chen,Yu-Heng Ding,Mei-Qi Zhao et al.
Zhuo Chen et al.
Background: Lung adenocarcinoma (LUAD) is the primary subtype of Non-small cell lung cancer (NSCLC) and a serious threat to human health. However, the precise molecular mechanisms in lung cancer remain largely unexplored....
Predictive model using systemic inflammation markers to assess neoadjuvant chemotherapy efficacy in breast cancer [0.03%]
预测乳腺癌新辅助化疗疗效的系统性炎症标志物模型
Yulu Sun,Yinan Guan,Hao Yu et al.
Yulu Sun et al.
Background: Pathological complete response (pCR) is an important indicator for evaluating the efficacy of neoadjuvant chemotherapy (NAC) in breast cancer. The role of systemic inflammation markers in predicting pCR and th...
A seven-LncRNA signature for prognosis prediction of patients with lung squamous cell carcinoma through tumor immune escape [0.03%]
通过肿瘤免疫逃逸预测肺鳞状细胞癌患者预后的七个长链非编码RNA标志物签名
Qiangqiang Ge,Zhong Lin,Xuequan Wang et al.
Qiangqiang Ge et al.
Background: Lung squamous cell carcinoma (LUSC) is a malignant disease associated with poor therapeutic responses and prognosis. Preliminary studies have shown that the dysregulation of long non-coding RNAs (LncRNAs) is l...
Transarterial chemoembolization for unresectable hepatocellular carcinoma: a comparative study between transradial and transfemoral approaches [0.03%]
经动脉化疗栓塞治疗不可切除的肝细胞癌：经桡动脉和股动脉途径的比较研究
Shun-Ting Bo,Jun Zhu,Li-Xiao He et al.
Shun-Ting Bo et al.
Background: While transarterial chemoembolization (TACE) has been performed using both the transfemoral approach (TFA) and the transradial approach (TRA) to date, the relative superiority of these techniques remains uncer...
Exploring the mechanism of action of succinic acid in ovarian cancer via single-cell sequencing of the tumor immune microenvironment [0.03%]
通过肿瘤免疫微环境的单细胞测序探索琥珀酸盐在卵巢癌中的作用机制
Jiao Zhao,Panpan Guo,Lili Zhao et al.
Jiao Zhao et al.
Background: The main treatments for ovarian cancer are surgery, chemotherapy, radiotherapy, and targeted therapy. Targeted therapy is a new treatment method that has emerged in recent years and relies on specific molecula...
Combination of MLo-1508 with sunitinib for the experimental treatment of papillary renal cell carcinoma [0.03%]
MLo-1508与索拉非尼联合治疗肾乳头状细胞癌的实验研究
Ângela Marques-Magalhães,Filipa Moreira-Silva,Inês Graça et al.
Ângela Marques-Magalhães et al.
Renal cell carcinoma (RCC) is the 14th most incident cancer worldwide, and no curative therapeutic options are available for advanced and metastatic disease. Hence, new treatment alternatives are urgently needed to tackle disease management...
RAS70 peptide targets multiforme glioblastoma by binding to the plasma membrane heat shock protein HSP70 [0.03%]
RAS70多肽通过与细胞膜HSP70蛋白结合靶向胶质肉瘤干细胞
Maxim Shevtsov,Natalia Yudintceva,Danila Bobkov et al.
Maxim Shevtsov et al.
Multiforme glioblastoma-homing peptides, particularly targeting plasma membrane-bound heat shock protein mHsp70, demonstrate great application potential for tumor theranostics. In the current study, to further increase the bioavailability a...
Recent advances in PLGA polymer nanocarriers for ovarian cancer therapy [0.03%]
卵巢癌治疗中PLGA聚合物纳米载体的最新进展
Tingjing You,Shengmin Zhang
Tingjing You
Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide, and early diagnosis and effective treatment have been the focus of research in this field. It is because of its late diagnosis, acquired resistance mechanisms, and sys...
The interrelated roles of RAB family proteins in the advancement of neoplastic growth [0.03%]
RAB家族蛋白在恶性肿瘤进展中的相互作用关系及各自作用
Yuxin Ji,Ruonan Li,Guohui Tang et al.
Yuxin Ji et al.
Rab Proteins, A Subfamily Of The Ras Superfamily Of Small Gtpases, Are Critical Regulators Of Intracellular Vesicular Trafficking, Which Is Intricately Linked To Various Cellular Processes. These Proteins Play Essential Roles Not Only In Ma...
Ultrasound-guided percutaneous radiofrequency ablation combined with anti-PD-1 for the treatment of prostate cancer: an experimental study [0.03%]
经皮超声引导下射频消融联合抗PD-1治疗前列腺癌的实验研究
Si Chen,Ruiqing Liu,Shaobo Duan et al.
Si Chen et al.
Background: This study seeks to investigate the potential synergistic effects of combining ultrasound-guided percutaneous radiofrequency ablation with anti-PD-1 therapy on prostate cancer, utilizing animal models. ...