CNN-TumorNet: leveraging explainability in deep learning for precise brain tumor diagnosis on MRI images [0.03%]
CNN-TumorNet：利用可解释性深度学习方法对MRI图像上的脑肿瘤进行精准诊断
Novsheena Rasool,Niyaz Ahmad Wani,Javaid Iqbal Bhat et al.
Novsheena Rasool et al.
Introduction: The early identification of brain tumors is essential for optimal treatment and patient prognosis. Advancements in MRI technology have markedly enhanced tumor detection yet necessitate accurate classificatio...
Integrating multi-omics and machine learning methods reveals the metabolism of amino acids and derivatives-related signature in colorectal cancer [0.03%]
整合多组学和机器学习方法揭示结直肠癌氨基酸及衍生物代谢相关标志物
Jian Yue,Huiying Fang,Qian Yang et al.
Jian Yue et al.
Objective: The metabolism of amino acids and derivatives (MAAD) is closely related to the occurrence and development of colorectal cancer (CRC), but the specific regulatory mechanisms are not yet clear. This study aims to...
Modeling Krebs cycle from liver, heart and hepatoma mitochondria, supported Complex I as target for specific inhibition of cancer cell proliferation [0.03%]
基于线粒体复合物I靶向抑制活肝、心和肝癌细胞系克氏循环的数学模型
Luz Hernández-Esquivel,Isis Del Mazo-Monsalvo,Silvia Cecilia Pacheco-Velázquez et al.
Luz Hernández-Esquivel et al.
Introduction: The Krebs cycle (KC) is an important pathway for cancer cells because it produces reduced coenzymes for ATP synthesis and precursors for cellular proliferation. Described changes in cancer KC enzyme activiti...
Qizhu Yuling prescription in the prevention of postoperative metastasis and recurrence of esophagus cancer: study protocol for a randomized, double-blind, placebo-controlled, multicenter clinical trial [0.03%]
启珠玉玲方预防食管癌术后转移复发的临床研究方案：随机、双盲、安慰剂对照多中心临床试验
Miao Kong,Bowen Xu,Guanghui Zhu et al.
Miao Kong et al.
Background: Esophageal cancer (EC) is a malignant tumor with a high recurrence and metastasis rate and poor prognosis. In 2024, China ranked first in the world in terms of new EC cases and deaths. Surgery is the main trea...
Promising outcomes of the PD-L1 inhibitor Socazolimab in recurrent and metastatic cervical cancer: a case report [0.03%]
新型PD-L1抑制剂斯鲁利单抗治疗复发及转移性宫颈癌的临床效果观察：1例报告
Zichao Xu,Minjie Wang,Long Gong et al.
Zichao Xu et al.
Recurrent and metastatic advanced cervical cancer carries a poor prognosis, and there is currently no standardized treatment regimen. Immunotherapy, as an emerging and effective treatment strategy, has attracted significant attention. Socaz...
Advantages of time-dependent diffusion MRI for quantitative microstructural mapping in breast tumors [0.03%]
时间依赖扩散磁共振成像乳腺肿瘤定量微结构mapping优势分析研究论文
Lei Bao,Sijie Li,Zhuo Wang et al.
Lei Bao et al.
Objectives: Time-dependent diffusion MRI (TD-MRI) can measure tumor tissue microstructure, but its effectiveness in differentiating benign from malignant breast tumors is unclear. This study aims to investigate the diagno...
Prognostic significance of ALK high expression in SCLC: a 9-year cohort analysis [0.03%]
ALK高表达在SCLC中的预后价值：一项为期9年的队列分析研究
Jinhe Xu,Wenting Zhang,Feilai Xie et al.
Jinhe Xu et al.
Purpose: The aim of this study was to investigate the prognostic value of the abnormal expression of anaplastic lymphoma kinase (ALK) protein in patients with small cell lung cancer (SCLC) based on 9-year data from our ce...
Lenvatinib-induced pemphigus erythematosus in hepatocellular carcinoma: a unique case report [0.03%]
肝细胞癌患者使用仑伐替尼诱发的天疱疮样皮疹：一例独特病例报告
Xiaoqing Li,Suhua Ma,Qing She et al.
Xiaoqing Li et al.
Adjuvant lenvatinib in combination with transarterial chemoembolization (TACE) has demonstrated prolonged disease-free survival in hepatocellular carcinoma patients at high risk of recurrence post-resection. Here, we present the case of a 6...
Learning curve of transanal minimally invasive surgery for rectal neoplasm [0.03%]
经肛门微创手术治疗直肠肿瘤的学习曲线
Xingwang Li,Shaoqing Guo,Kunhou Yao et al.
Xingwang Li et al.
Objectives: The field of view through transanal endoscopic provides new treatment approaches for solving complex clinical problems. TAMIS belongs to single-port endoscopic surgery, and the operation is complex. Analyzing ...
To explore the risk factors of lymphovascular invasion in patients with upper tract urothelial carcinoma and construct a prediction model [0.03%]
上尿路尿路上皮癌淋巴管血管侵犯的风险因素探讨及列线图模型构建
Qinghui Li,Pengtao Wei,Yanjie Kang et al.
Qinghui Li et al.
Background and objective: To explore the risk factors and construct a prediction model of the lymphovascular invasion (LVI) in patients with upper tract urothelial carcinoma (UTUC). ...