Clinicopathologic correlates of Ewing (FET::ETS-rearranged) sarcoma and non-Ewing undifferentiated small round cell sarcomas across skeletal and extraskeletal sites [0.03%]
EWS基因重排阳性尤因肉瘤与原发于骨和软组织的非尤因圆形小细胞肿瘤的临床病理特征对比研究
Rola H Ali,Hind S Al-Otaibi,Samer A K Abdulmoneim et al.
Rola H Ali et al.
Background: FET::ETS-rearranged Ewing sarcoma (ES) and non-Ewing undifferentiated small round-cell sarcomas (SRCSs) comprise a morphologically overlapping yet molecularly diverse group of aggressive sarcomas. They differ ...
Case Report: Niraparib-abiraterone in HRR-mutated metastatic castration-resistant prostate cancer: clinical insights from five cases [0.03%]
病例报告：Niraparib-阿比特龙治疗HRR基因突变的转移性去势抵抗性前列腺癌：五例患者的临床启示
Ismaela Anna Vascotto,Martina Catalano,Jacopo Venturini et al.
Ismaela Anna Vascotto et al.
Background: Combination therapy with the PARP inhibitor niraparib and the androgen-receptor inhibitor abiraterone acetate plus prednisone (AAP) has recently shown improvement in radiographic progression-free survival (rPF...
Immune-inflammation index as prognostic markers in metastatic castration-resistant prostate cancer: a systematic review and meta-analysis [0.03%]
免疫炎症指数作为转移性去势抵抗性前列腺癌预后标志物的系统评价和meta分析
Zitong Qin,Runzhang Liu,Suoshi Jing et al.
Zitong Qin et al.
Introduction: Systemic inflammation is closely linked to tumor progression and immune dysfunction. Simple blood-derived immune-inflammatory indices may provide cost-effective prognostic stratification for metastatic castr...
Anlotinib-temozolomide combination achieves durable response in multimodal-resistant primary breast angiosarcoma with skull base metastasis and dural involvement: a case report [0.03%]
安罗替尼-替莫唑胺联合治疗多模式耐药原发乳腺血管肉瘤并颅底转移伴硬脑膜侵犯的病例报告
Shujie Song,Weiyi Chen,Xixi Li et al.
Shujie Song et al.
Primary breast angiosarcoma is an exceedingly rare malignancy with a high propensity for hematogenous metastasis, though skull base and dural involvement have never been reported. We present a 52-year-old woman diagnosed with stage IIA prim...
Clinicopathological characteristics and prognosis of early-onset colorectal cancer: a retrospective cohort study [0.03%]
早发结直肠癌的临床病理特征及预后：回顾性队列研究
Shuping Lian,Guibin Zheng,Yixin Lin et al.
Shuping Lian et al.
Objective: To investigate the clinical and pathological characteristics of patients with early-onset colorectal cancer (EOCRC) and to evaluate their impact on postoperative overall survival (OS) within the observed follow...
BRCA testing patterns in breast cancer over time in the United States: challenges and opportunities for improvement [0.03%]
美国乳腺癌患者中BRCA基因检测的时间趋势及其面临的挑战和机遇
Kathryn Mishkin,Erin Mandal,Deborah Tallarigo et al.
Kathryn Mishkin et al.
Testing for germline mutations in breast cancer genes (gBRCAm) is recommended to inform treatment decisions for patients with breast cancer (BC); however, not all eligible patients will undergo testing. This targeted literature review summa...
Prognostic value of prognostic nutritional index in breast cancer patients receiving neoadjuvant therapy: a systematic review and meta-analysis [0.03%]
术前新辅助治疗乳腺癌患者预后营养指数的预测价值系统评价和meta分析
Meihui Shan,Ziqian Zhao,Munawar Anwar et al.
Meihui Shan et al.
Objective: Although the prognostic utility of the prognostic nutritional index (PNI) in breast cancer (BC) treated with neoadjuvant chemotherapy (NACT) has been widely reported, the available evidence remains inconsistent...
ALBI-SII grade: a novel prognostic indicator superior to Child-Pugh score for long-term survival in hepatocellular carcinoma and its nomogram construction and validation [0.03%]
ALBI-SII分级：一种优于Child-Pugh评分的长期生存期预后指标用于肝细胞癌及列线图构建和验证
Can Li,Xiaopeng Yu,Renyi Yang et al.
Can Li et al.
Introduction: Prognostic heterogeneity is common in patients with hepatocellular carcinoma (HCC) within the same clinical stage. While the albumin-bilirubin (ALBI) score and systemic immune-inflammation index (SII) have i...
Mechanistic drivers of PD-L1/CTLA-4 checkpoint inhibitor-associated immune toxicity and systemic organ injury [0.03%]
PD-L1/CTLA-4检查点抑制剂相关免疫毒性和全身器官损伤的机制驱动因素
Junfeng Chen,Lin Zhang,Minqqiang Gao et al.
Junfeng Chen et al.
Background: Immune checkpoint inhibitors targeting PD-1/PD-L1 and CTLA-4 have substantially improved outcomes in multiple malignancies, but they may also trigger dysregulated immune activation accompanied by systemic toxi...
Cancer care continuity under 2026 regional gulf conflict: experiences and a resilience framework from the Gulf States [0.03%]
2026年海湾冲突下的癌症连续护理：海湾国家的经验和韧性框架
Humaid O Al-Shamsi,Saeed Rafii,Maha Al Sindi et al.
Humaid O Al-Shamsi et al.
Armed conflicts and geopolitical instability pose significant risks to healthcare systems, particularly for patients with cancer who rely on uninterrupted, resource-intensive care pathways. Disruptions to diagnostic services, pharmaceutical...