Incidental intraoperative discovery of a Wolffian tumor in a postmenopausal woman: a case report and literature review [0.03%]
绝经后女性术中偶然发现 Wolffi 肿瘤的病例报道及文献复习
Dong-Mei Li,Ming-Rong Xi,Xi Zeng
Dong-Mei Li
Background: Female adnexal tumor of Wolffian origin (FATWO) is an exceedingly rare gynecologic neoplasm characterized by nonspecific clinical manifestations and diagnostic challenges. This article presents a case of an in...
Development of an AI-driven digital assistance system for real-time safety evaluation and quality control in laparoscopic liver surgery [0.03%]
一种AI驱动的数字辅助系统的发展，用于腹腔镜肝手术中实时安全评估和质量控制
Zi-Yang Peng,Zhi-Bo Wang,Yan Yan et al.
Zi-Yang Peng et al.
Background: By performing AI-driven workflow analysis, intelligent surgical systems can provide real-time intraoperative quality control and alerts. We have upgraded an Intelligent Surgical Assistant (ISA) through integra...
Case report: Anlotinib plus oral etoposide: a potential salvage therapy based on insights from EGFR-TKI-resistant SCLC transformation PDX and clinical settings [0.03%]
病例报告：安罗替尼联合口服依托泊苷可能是基于EGFR-TKI耐药SCLC转化PDX和临床背景启示的潜在挽救治疗方案
Zixi Wang,Xiaoyu Li,Lili Jiang et al.
Zixi Wang et al.
Small cell lung cancer (SCLC) transformation is one of the resistance mechanisms to epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment in patients with lung adenocarcinoma (LUAD). Platinum-etoposide chemotherapy...
Domenico Ribatti,Roberto Tamma,Giuseppe Ingravallo et al.
Domenico Ribatti et al.
Targeting tumor angiogenesis is an advancement in the treatment of hematological malignancies. This article summarizes the most recent advancements in the use of anti-angiogenic agents in the treatment of human lymphomas. Preclinical and cl...
The effect of tislelizumab on complete and pathological complete response in non-small cell lung cancer: a systematic review and meta-analysis [0.03%]
替雷利珠单抗对非小细胞肺癌完全缓解和病理完全缓解的影响：系统评价和Meta分析
Qian Feng,Xiaoxia Yan,Liping Gao et al.
Qian Feng et al.
Background: Immune checkpoint inhibitors have transformed non-small cell lung cancer (NSCLC) treatment, and while overall survival (OS) and progression-free survival (PFS) are well-established, a comprehensive meta-analys...
Case Report: Esophago-pleural fistula found by the squamous cells from pleural effusion [0.03%]
病例报告：通过胸水找到食管气管瘘
Shu Li,Zesen Han,Xue Zhang et al.
Shu Li et al.
This report describes a case of esophago-pleural fistula (EPF) in an history of esophageal cancer (EC) patient, initially missed on CT but identified via squamous cells in pleural effusion. EPF is rare and challenging to diagnose due to sub...
Enhancing clinical diagnosis of laryngeal cancer through fusion-based transfer learning with Osprey Optimisation Algorithm using histology images [0.03%]
基于融合的迁移学习利用鱼鹰优化算法通过组织学图像提高声门癌临床诊断准确性
Nouf Al-Kahtani,Mona M Jamjoom,Mohamad Khairi Ishak et al.
Nouf Al-Kahtani et al.
Background: Laryngeal squamous cell carcinoma is the most commonly diagnosed neck and head cancer. In contrast, the primary stage of pre-malignant and laryngeal cancer (LC) has to be handled with early diagnosis and treat...
Context-dependent rewiring of dual-function proteins in cancer: a sequential strategy to restore apoptosis [0.03%]
癌症中具有双重功能蛋白质的条件依赖性重构：恢复凋亡的顺序策略
Leon Strzadala
Leon Strzadala
Resistance to programmed cell death is a defining hallmark of cancer and a persistent barrier to successful therapy. Dual-function proteins such as p53, Ras, HIF-1α, BNIP3, and NF-κB act as molecular switches that determine cell fate betw...
Wentao Xie,Xinye Jiang,Jingying Huang et al.
Wentao Xie et al.
Acute myeloid leukemia (AML) is a highly heterogeneous malignant hematological neoplasm. Although standard diagnostic procedures have been established, traditional methods still face limitations with regard to efficiency, accuracy, and stan...