Case Report: Medullary carcinoma of the pancreas with MLH1 promoter hypermethylation, induced deficient mismatch repair, successfully treated with an immune checkpoint inhibitor [0.03%]
病例报告：携带MLH1启动子高甲基化并由其诱导错配修复缺陷的胰腺髓样癌对免疫检查点抑制剂治疗有效
Koushiro Ohtsubo,Shigeki Sato,Hiroyuki Sakaguchi et al.
Koushiro Ohtsubo et al.
We report the case of a 75-year-old woman with a pancreatic body mass. Pathological findings from endoscopic ultrasonography-guided fine-needle aspiration revealed medullary carcinoma of the pancreas (MCP). Deficient mismatch repair (dMMR) ...
EFTUD2 is a promising diagnostic and prognostic indicator involved in the tumor immune microenvironment and glycolysis of lung adenocarcinoma [0.03%]
EFTUD2是一个有希望的诊断和预后指标参与肺腺癌肿瘤免疫微环境和糖酵解作用
Ankang Yin,Yufan Xu,Xiyang Su et al.
Ankang Yin et al.
Background: Elongation Factor Tu GTP Binding Domain Containing 2 (EFTUD2), a conserved spliceosomal GTPase, is involved in craniofacial development and various cancers, but its role in lung adenocarcinoma (LUAD) remains u...
Survival outcomes and prognostic factors in surgically treated adult pilocytic astrocytomas [0.03%]
成人 pilocytic 星形细胞瘤手术治疗的生存结果及预后因素
Sanghyeok Park,Jung Han Seo,Sang Woo Song et al.
Sanghyeok Park et al.
Purpose: Pilocytic astrocytomas (PA) in adult patients are rare and the efficacy of postoperative adjuvant treatments remains unclear. This study aims to investigate the survival outcome and prognostic factors in surgical...
Combining with immunotherapy is an emerging trend for local treatment of colorectal cancer liver metastases: a bibliometric analysis [0.03%]
免疫治疗与局部治疗联合是结直肠癌肝转移的新趋势——文献计量分析研究
Bin Shao,Ya-Shi Yin,Yi-Nuo Wei et al.
Bin Shao et al.
Background: A growing body of evidence has demonstrated the expanding role of local treatment in managing colorectal cancer liver metastases (CRCLM). To identify current research trends and forecast future directions, we ...
Lena Specht
Lena Specht
Primary cutaneous lymphomas are highly radiosensitive. X-rays work well for localized cutaneous lymphomas. However, if disseminated in the skin and covering larger areas, as is commonly the case with the most common type, mycosis fungoides,...
Advancements in research on the precise eradication of cancer cells through nanophotocatalytic technology [0.03%]
纳米光催化技术在精准消灭癌细胞研究中的进展
Changyang Yao,Chensong Zhang,Dongwei Fan et al.
Changyang Yao et al.
The rapid development of nanotechnology has significantly advanced the application of nanophotocatalysis in the medical field, particularly for cancer therapy. Traditional cancer treatments, such as chemotherapy and radiotherapy, often caus...
MRI-based deep transfer learning models for predicting progesterone receptor expression in meningioma [0.03%]
基于MRI的深度迁移学习模型预测脑膜瘤孕激素受体表达
Song Gao,Li Zhao,Nan Li et al.
Song Gao et al.
Objectives: The progesterone receptor (PR) is an important biomarker in meningiomas, influencing tumor growth, prognosis, and potential treatment options. The objective of this study was to predict PR expression in mening...
The role and regulatory mechanism of lysosome associated protein transmembrane 4β in tumors [0.03%]
肿瘤中lysosome关联跨膜蛋白4β的作用和调控机制研究
Yuteng Yang,Yumei Li,Yaqi Wang et al.
Yuteng Yang et al.
The oncogene LAPTM4B (encoding lysosome-associated protein transmembrane-4β), first cloned in hepatocellular carcinoma cells, is located on chromosome 8q22.1 and encodes two isoforms, LAPTM4B-35 and LAPTM4B-24. LAPTM4B proteins have four t...
Common haematological malignancies in Northeastern Nigeria: a multi-centre study of their pattern, distribution and treatment challenges [0.03%]
尼日利亚东北部常见血液系统恶性肿瘤的多中心研究：其模式、分布和治疗挑战
Rufai Abdu Dachi,Falmata Grema Mustapha,Jesini James et al.
Rufai Abdu Dachi et al.
Background: Haematological malignancies (HMs) are primary cancers of the blood and blood-forming organs. They are heterogeneous and of diverse clinical features, treatment protocols and prognoses. They constitute a signif...
Identification of MAD2L1 as a novel biomarker for hepatoblastoma through bioinformatics and machine learning approaches [0.03%]
通过生物信息学和机器学习方法鉴定MAD2L1作为肝母细胞瘤的新生物标志物
Ying He,Xiwei Hao,Bin Hu et al.
Ying He et al.
Objective: This study aims to identify potential biomarkers for Hepatoblastoma (HB) using bioinformatics and machine learning, and to explore their underlying mechanisms of action. ...