Vaccine therapies for glioma: clinical frontiers and potential breakthrough [0.03%]
脑胶质瘤的疫苗治疗：临床前沿与潜在突破点
Ying Xing,Caixia Liu,Yunfeng Feng et al.
Ying Xing et al.
Glioma, the most common primary malignant brain tumor, is characterized by high recurrence and mortality rates. Its effective treatment remains a therapeutic challenge in clinical neuro-oncology. Despite over twenty years of exploring new t...
Knowledge graph and bibliometric analysis of inflammatory indicators in ovarian cancer [0.03%]
基于文献计量的卵巢癌炎症标志物知识图谱分析研究
Liyan Zhang,Linlin Guo,Haiyan Wang et al.
Liyan Zhang et al.
Background: Chronic inflammation is a type of inflammatory response that lasts for a relatively long period of time. Occurrence and development of many diseases are closely related to chronic inflammation. In the process ...
Postoperative pneumonia in patients with non-small cell lung cancer undergoing thoracoscopic surgery: What should we care about? [0.03%]
电视胸腔镜手术治疗非小细胞肺癌术后肺炎的危险因素分析及处理原则
Jinzhi You,Dandan Chen,Xiang Liu et al.
Jinzhi You et al.
Background: The prevention of postoperative pneumonia in patients with non-small cell lung cancer (NSCLC) undergoing thoracoscopic surgery holds significant clinical importance. This study aimed to evaluate the status quo...
PALB2 deficiency may sensitize H3K27M-mutant pediatric HGG cells to BMN673/talazoparib [0.03%]
PALB2缺陷可使H3K27M突变型儿童HGG细胞对BMN673/塔拉唑帕ibil敏感
Xiaowen Guan,Xinke Xu,Xiaolan Mo et al.
Xiaowen Guan et al.
Backgroud: Pediatric high-grade glioma (pHGG) with the histone H3 Lys27Met substitution (H3K27M) is a devastating disease with a high mortality rate in children and adolescents (from birth to 19 years of age). No effectiv...
Analysis of the molecular subtypes and prognostic models of anoikis-related genes in colorectal cancer [0.03%]
分析结直肠癌中与凋亡相关的分子亚型和预后模型
Lei Shen,Kang Hou,Jifeng Zhang et al.
Lei Shen et al.
Background: Colorectal cancer (CRC) is a malignant tumor originating from the epithelial cells of colon or rectum. Currently, the main treatment strategy is surgery with chemotherapy and radiotherapy, but the 5-year survi...
Bibliometric analysis combined with visualization on universal trends and hot topics of LOX family in human diseases: 1995 to 2025 [0.03%]
结合可视化的基质金属蛋白酶LOX家族在人类疾病领域的文献计量分析(1995-2025年)
Tingting Yang,Heng Li,Wenxuan Zhou et al.
Tingting Yang et al.
Introduction: Lysyl oxidase (LOX) is crucial for modifying collagen and elastin, thereby preserving tissue integrity. Aberrant LOX activity has been associated with a multitude of health disorders, including cutaneous, pu...
Current research status on HER2 protein expression levels and the efficacy of targeted therapy in breast cancer [0.03%]
HER2蛋白表达水平与乳腺癌靶向治疗疗效关系的现状研究
Jiani Liu,Xinyu Peng,Yang Yang et al.
Jiani Liu et al.
This review summarizes the relationship between HER2 protein expression and the efficacy of three anti-HER2 targeted therapies in breast cancer patients: monoclonal antibodies, antibody-drug conjugates (ADCs), and tyrosine kinase inhibitors...
Assessment of prostate cancer aggressiveness through the combined analysis of prostate MRI and 2.5D deep learning models [0.03%]
前列腺MRI与2.5D深度学习模型的联合分析评估前列腺癌的侵袭性
Yalei Wang,Yuqing Xin,Baoqi Zhang et al.
Yalei Wang et al.
Objective: Prostate cancer is prevalent among older men. Although this malignancy has a relatively low mortality rate, its aggressiveness is critical in determining patient prognosis and treatment options. This study ther...
Efficacy and safety of cadonilimab (PD-1/CTLA-4 bi-specific antibody) and adjuvant anti-angiogenesis therapy in treated, recurrent, or metastatic cervical cancer [0.03%]
卡度尼利单抗(PD-1/CTLA-4双特异性抗体)联合血管生成抑制剂治疗既往经过一线及以上系统治疗的复发或转移性宫颈癌的疗效和安全性：一项开放性、多中心II期临床研究
Fang Zhou,Shushu Liu,Ying Zuo et al.
Fang Zhou et al.
Background: Combined immunotherapy and antiangiogenic therapy have exhibited synergistic antitumor effects in several cancers. The prognosis of recurrent or metastatic cervical cancer (r/mCC) is poor, especially for patie...
Prevalence of human papillomavirus genotypes in Latvia among women participating in cervical cancer screening [0.03%]
拉脱维亚宫颈癌筛查女性人乳头瘤病毒基因型的流行病学研究
Anna Stasulane,Justine Grundmane,Kristiana Sulte et al.
Anna Stasulane et al.
Background and objectives: The propensity of human papillomavirus (HPV) to cause cervical cancer is linked to specific genotypes that vary in carcinogenicity. This study aims to provide insight into the most prevalent HPV...