SPP1+ tumor-associated macrophages define a high-risk subgroup and inform personalized therapy in hepatocellular carcinoma [0.03%]
SPP1+肿瘤相关巨噬细胞定义了高危肝癌亚群并可用于指导肝细胞癌的个性化治疗
Wei-Xuan Xu,Ya-Mei Ye,Jia-Lin Chen et al.
Wei-Xuan Xu et al.
Introduction: Recently, contrary to attacking cancer cells, the tumor microenvironment (TME) with genomic stability and vulnerable nature has emerged as promising therapeutic targets in hepatocellular carcinoma (HCC). Wit...
The advances of DNA methylation in the liquid biopsy for the detection of lung cancer [0.03%]
DNA甲基化在肺癌液体活检中的研究进展
Yuxuan Chen,Shuang Peng,Cailian Wang
Yuxuan Chen
Lung cancer is the most common cancer in the world and the leading cause of cancer death. The absence of effective early detection is one of the major contributors to high mortality rate of lung cancer. Liquid biopsy has the potential to be...
Global research trends in tryptophan metabolism and cancer: a bibliometric and visualization analysis (2005-2024) [0.03%]
2005-2024年色氨酸代谢与癌症的全球研究趋势：基于文献计量和可视化分析
Huanhuan Ma,Ran Ding,Junwen Wang et al.
Huanhuan Ma et al.
Background: In recent years, tryptophan metabolism has gained increasing attention for its pivotal role in shaping the tumor immune microenvironment and promoting cancer progression. As a result, it has become a central t...
Advances in radiotherapy enhancing the efficacy of immune checkpoint inhibitors in malignant [0.03%]
放射治疗在恶性肿瘤中增强免疫检查点抑制剂疗效的进展
Yao Liao,Jinjing Deng,Xiyue Yang et al.
Yao Liao et al.
The introduction of immune checkpoint inhibitors (ICIs) has facilitated the elucidation of the mechanisms underlying the remote effects observed in tumor therapy and has demonstrated significant promise for treating several advanced tumors....
Angiosarcoma: a systematic review of biomarkers in diagnosis, prognosis, and therapeutic strategies [0.03%]
血管肉瘤的生物标志物：系统性综述在诊断、预后及治疗策略中的应用
Huyen Thuc Tran Luong,Sofie Vercammen,Ario de Marco et al.
Huyen Thuc Tran Luong et al.
Angiosarcoma is a rare, aggressive vascular malignancy characterized by rapid proliferation, early metastasis, and limited therapeutic options, resulting in poor prognosis. The etiopathogenesis of AS remains elusive and diagnosis is challen...
Primary giant hepatic neuroendocrine neoplasms in a young adult: case report and literature review [0.03%]
年轻成人原发巨大型肝神经内分泌肿瘤一例并文献复习
Xue Luo,Xingxing Bie,Na Luo et al.
Xue Luo et al.
Primary hepatic neuroendocrine neoplasms (PHNENs) are a rare type of neuroendocrine tumors originating in the liver. These tumors are characterized by non-specific clinical symptoms and atypical imaging features, making differentiation from...
Mapping the knowledge network of extracellular vesicles and angiogenesis in tumor-immune communication: a scientometric analysis [0.03%]
肿瘤免疫相互作用中的外泌体和血管生成知识网络的计量分析测绘
Kai Wang,Dufu Lu
Kai Wang
Objective: This study aims to explore the cooperative networks among authors, nations, organizations, and publications specializing in extracellular vesicle-angiogenesis, to evaluate the foundational knowledge, and to pin...
Clinical utility of various liquid biopsy samples for the early detection of ovarian cancer: a comprehensive review [0.03%]
液体活检在卵巢癌早期诊断中的临床应用价值：全面回顾
Yueqi Feng,Wanjun Yang,Jingyu Zhu et al.
Yueqi Feng et al.
Ovarian cancer (OC) is a highly lethal gynecologic malignancy because of the absence of specific early symptoms and reliable biomarkers, most OC patients are often diagnosed at advanced stages, resulting in poor prognosis. Traditional tissu...
Primary hepatic leiomyosarcoma concurrent with early-stage lung adenocarcinoma: a rare case report [0.03%]
原发性肝平滑肌肉瘤合并早期肺腺癌一例报告
Weizhong Peng,Xiaohui Xiao,Lu Li et al.
Weizhong Peng et al.
Primary hepatic leiomyosarcoma (PHL) is an extremely rare malignant mesenchymal tumor, accounting for less than 2% of all primary hepatic malignancies. We report a case of a 46-year-old female who presented with a one-year history of abdomi...
Case Report: Three cases of lung large cell neuroendocrine carcinoma with clinicopathological features of SMARCA4 (BRG1) deficiency [0.03%]
病例报告：三例具有SMARCA4(BRG1)缺陷临床病理特征的肺大细胞神经内分泌癌
Fangfang Zou,Jingdan Jia,Yizeng Wang et al.
Fangfang Zou et al.
Objective: To investigate the clinicopathological characteristics, differential diagnosis and potential therapeutic targets of SMARCA4-deficient large cell neuroendocrine carcinoma (SD-LCNEC) in the lung. ...