Intraplacental choriocarcinoma and spontaneous fetomaternal hemorrhage: Uncovering diagnostic clues in a challenging case [0.03%]
胎盘内绒毛膜癌和自发性胎儿母体出血：一个复杂病例的诊断线索分析
Li Wang,Xuri Li,Dongfang Bai et al.
Li Wang et al.
Background: Intraplacental choriocarcinoma (IC) is an extremely rare malignancy of the placenta that is often associated with fetomaternal hemorrhage (FMH). This combination is challenging to diagnose antepartum and is as...
Apparent diffusion coefficient predicts MGMT status in adult-type diffuse gliomas and is correlated with Ki-67 proliferation index [0.03%]
表观扩散系数可预测成人型弥漫性胶质瘤IDH状态及与Ki-67增殖指数相关性研究
Feng-Ying Zhu,Li-Yong Zhuo,Tian-Da Wang et al.
Feng-Ying Zhu et al.
Purpose: To evaluate the predictive value of apparent diffusion coefficient (ADC) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and its correlation with Ki-67 proliferation index in adult-type dif...
Molecular mechanism of LncRNA MALAT1 in regulating hepatocellular carcinoma progression via the miR-383-5p/PRKAG1 axis and its role in the tumor immune microenvironment [0.03%]
长链非编码RNA MALAT1在肝细胞癌进展中的分子机制及其在肿瘤免疫微环境中的作用研究：通过miR-383-5p/PRKAG1轴调节
Rui Zhang,Mingze Li,Shan Lu et al.
Rui Zhang et al.
Background: Hepatocellular carcinoma (HCC) is a highly prevalent malignant tumor worldwide, and its development is closely associated with dysregulated non-coding RNA expression. The long non-coding RNA MALAT1 is overexpr...
Effects of parthenolide on amino acid metabolism and oxidative stress in lung adenocarcinoma based on quantitative proteomic analysis, targeted amino acid metabolomics, network pharmacology, and experimental validation [0.03%]
基于定量蛋白质组学、靶向氨基酸代谢组学、网络药理学及实验验证的青阳参酮对肺腺癌患者支气管上皮细胞氨基酸代谢和氧化应激的影响研究
Jiye Liu,Yu Liu,Jiachun Li et al.
Jiye Liu et al.
Background: Lung adenocarcinoma (LUAD) causes millions of deaths annually worldwide. Parthenolide (PTL), extracted from traditional Chinese herbal medicines, has various biological activities. In this study, we investigat...
A profile of lung cancer in the young population with a highlight on the Indian perspective [0.03%]
印度年轻肺癌患者流行病学特点分析
Ghazal Tansir,Aparna Sharma,Sachin Khurana et al.
Ghazal Tansir et al.
Non-small cell lung cancer (NSCLC) is a disease primarily of the elderly, with a small proportion of patients in the younger age group. This subgroup of younger patients accounts for 1-10% among the Asian population and 2% in Caucasians. Wh...
Boron neutron capture therapy for melanoma: recent advances and future prospects [0.03%]
硼中子俘获治疗黑色素瘤：近期进展与未来前景
Yuanyang Sun,Yun Wang,Shukun Mu et al.
Yuanyang Sun et al.
Boron neutron capture therapy (BNCT) is a unique radiotherapy modality that targets and destroys selectively tumor cells that have absorbed boron, while leaving surrounding healthy cells unharmed. Over the course of the last nearly 40 years...
Interactions between ALKBH5 and reader proteins in tumors: functions and molecular mechanisms [0.03%]
肿瘤中ALKBH5与阅读蛋白的互作：功能及分子机制
Jiahui Ou,Bingchen Liu,Yi Yu et al.
Jiahui Ou et al.
RNA methylation modifications are widespread in eukaryotes and prokaryotes, with N6-methyladenosine (m6A) methylation being the most prevalent internal modification in eukaryotic mRNA and having become a prominent focus of tumor research in...
Integrating intratumoral, peritumoral, and clinical features in an ultrasound-based radiomics model: contributions and synergies for predicting microvascular invasion in hepatocellular carcinoma [0.03%]
基于超声影像组学模型预测肝细胞癌微血管侵犯的瘤内、瘤周及临床因素贡献及联合作用分析
Hong Fu,Yanhua Huang,Baochun Lu et al.
Hong Fu et al.
Background: Microvascular invasion (MVI) is a critical determinant of poor prognosis in hepatocellular carcinoma (HCC). Accurate preoperative prediction of MVI is essential for optimizing surgical and therapeutic strategi...
Anesthesia is a potent determinant of ultra-high dose rate sparing in the murine total abdominal irradiation model [0.03%]
麻醉是小鼠全腹照射模型中超高剂量率容许量的强力决定因素
Armin D Tavakkoli,William W Daley,David I Hunter et al.
Armin D Tavakkoli et al.
Introduction: Radiation therapy is a mainstay of treatment for numerous gastrointestinal (GI) malignancies, where our ability to deliver dose to tumors is limited by acute GI toxicity. Ultra-high dose-rate (UHDR) 'FLASH' ...
Gut microbiome with RAS mutation and chemotherapy response in patients with advanced or metastatic colorectal cancer: a pilot, exploratory study [0.03%]
KRAS突变和化疗反应与晚期或转移性结直肠癌患者的肠道微生物组的关系：一项初步探索性研究
Jwa Hoon Kim,Boyeon Kim,Jiwon Lee et al.
Jwa Hoon Kim et al.
The gut microbiome plays a pivotal role in tumor-microenvironment interactions, inflammation modulation, and immune regulation, thereby affecting the response to anticancer therapy. This pilot study investigated gut composition according to...