Habitat radiomics based on CT for assessing BRCA mutation status in patients with high-grade serous ovarian cancer: a multicenter study [0.03%]
基于CT的影像组学评估高级别浆液性卵巢癌患者BRCA突变状态的多中心研究
Shuai Zhang,Huayuan Yang,Feng Wang et al.
Shuai Zhang et al.
Purpose: This study aims to evaluate the potential of CT-based habitat radiomics in predicting BRCA mutation status in patients with high-grade serous ovarian cancer (HGSOC). The goal is to identify radiomic features from...
Germ-line exon 21 EGFR V831H mutation in advanced NSCLC resistance to almonertinib: a case report [0.03%]
阿洛美替尼治疗晚期NSCLC发生EGFR基因第21外显子V831H新生 germline 突变的病例报告
Daxia Cai,Jian Lou,Yanyan Zhu et al.
Daxia Cai et al.
Background: Germ-line EGFR mutations are rare, and their clinical significance, particularly regarding response to tyrosine kinase inhibitors (TKIs), remains poorly defined. The EGFR V831H (also known as R831H) mutation i...
Case Report: Paradoxical responses to pasireotide in a patient with a silent corticotroph adenoma that transformed into an ACTH-secreting adenoma [0.03%]
病例报告：silent corticotroph腺瘤转变为ACTH分泌型腺瘤患者的肽 tirazotide疗效悖论反应
Anna Brona,Aleksandra Zdrojowy-Wełna,Marek Bolanowski
Anna Brona
Introduction: There are only a few reported cases of paradoxical response to pasireotide treatment of adrenocorticotropic hormone (ACTH)-secreting tumors, mostly aggressive macroadenomas, which led to therapy discontinuat...
Efficacy, safety, and survival outcomes of radiotherapy combined with nimotuzumab following induction chemotherapy in locally advanced head and neck cancer [0.03%]
诱导化疗后放疗联合尼莫单抗在局部晚期头颈部肿瘤治疗中的疗效、安全性和生存结果的评估：一项随机、双盲、安慰剂平行对照的Ⅲ期临床试验
Yanjie Zhuang,Chen Chen,Zhenxi Xu et al.
Yanjie Zhuang et al.
Objective: To evaluate the efficacy, safety, and impact on survival of adding nimotuzumab to radiotherapy after induction chemotherapy in patients with locally advanced head and neck cancer (HNC). ...
Nodal status dictates divergent prognostic drivers in oral squamous cell carcinoma: metabolic burden in pN0 vs. sarcopenia and nodal burden in pN [0.03%]
淋巴结状态决定了口腔鳞状细胞癌中不同的预后驱动因素：pN0中的代谢负担与pN中的肌少症和淋巴结负荷
Shihui Shen,Wugang Zhou,Yuhua Hu et al.
Shihui Shen et al.
Objectives: Oral squamous cell carcinoma (OSCC) exhibits heterogeneous outcomes based on nodal status, complicating personalized prognosis. This study aimed to identify nodal-specific prognostic factors in OSCC by integra...
SpectraNet: a novel model for polyp segmentation leveraging a spectral-guided mixture of functional experts [0.03%]
基于光谱引导的功能专家混合模型的息肉分割算法
Zhong Liu,Jing Ling
Zhong Liu
Automated and precise polyp segmentation from colonoscopy images is critical for the early diagnosis of colorectal cancer. However, this task is challenged by the ambiguous and low-contrast boundaries of polyps, which often blend with the s...
Circulating cell-free DNA as an integrative biomarker in breast cancer: correlation with molecular subtypes, mutation status, and treatment response [0.03%]
循环细胞游离DNA作为乳腺癌整合标志物：与分子亚型、突变状态和治疗反应的相关性
Ranjana Solanki,Ashmeet Kaur,Ravindra Gothwal et al.
Ranjana Solanki et al.
Background: Cell-free DNA (cfDNA) is an emerging non-invasive biomarker in oncology. While its diagnostic and prognostic roles in breast cancer are established, limited studies have examined cfDNA dynamics in relation to ...
Targeted and systemic therapies for recurrent adult ependymomas: real-world outcomes from a single institution and concise literature review [0.03%]
成人复发性室管膜瘤的靶向及系统治疗：单一机构的真实世界结果和简要文献回顾
Marta Maccari,Alberto Bosio,Mario Caccese et al.
Marta Maccari et al.
Background: Recurrent adult ependymomas lack standard systemic therapies and evidence on chemotherapy and targeted agents is limited. This study aimed to retrospectively evaluated outcomes of systemic therapies, including...
Diagnostic value of cellular inflammatory markers in CNS tumor patients undergoing glucocorticoid therapy [0.03%]
糖皮质激素治疗神经系统肿瘤患者的细胞炎性标志物诊断价值分析
Sofia Sklyar,Daria Sitovskaya,Nataliya Dryagina et al.
Sofia Sklyar et al.
Introduction: While inflammation is recognized as a key driver of solid tumor progression, the diagnostic and pathophysiological relevance of cellular inflammatory biomarkers in central nervous system (CNS) neoplasms rema...
Early efficacy and safety of spinal endoscopy assisted anterior cervical discectomy and fusion in the treatment of cervical spondylotic myelopathy [0.03%]
内镜辅助颈椎前路手术治疗颈椎病的近期疗效及安全性分析
Haijun Ma,Lijuan Zhan,Mingkui Shen et al.
Haijun Ma et al.
Purpose: To introduce a new surgical approach for spinal endoscopy assisted anterior cervical discectomy and fusion (Endo-ACDF) in treating cervical spondylotic myelopathy (CSM) and to report the clinical results after a ...