Successful remission induction therapy with azacitidine and venetoclax for a treatment-naive elderly patient with ETP/myeloid mixed-phenotype acute leukemia: a case report [0.03%]
阿扎胞苷和维奈克拉诱导治疗ETP/髓系混合表型急性白血病疗效良好：1例初治老年患者的报道
Kaikai Huang,Yanbin Pang
Kaikai Huang
Background: Mixed-phenotype acute leukemia (MPAL) is a rare acute leukemia for which data are currently not available to guide therapy. It has a poor outcome, particularly in elderly patients. ...
Lung cancer associated with cystic airspaces: current status and challenges [0.03%]
与肺囊性气腔相关的肺癌：现状及挑战
Linlin Wang,Yong Feng,Shiyuan Song et al.
Linlin Wang et al.
Lung cancer associated with cystic airspaces (LCCA) refers to primary lung cancers presenting with cystic airspaces accompanied by solid components, representing a relatively uncommon imaging and pathological phenotype. Although high-resolu...
A compilation of 13 patients with metastatic colorectal cancer and concomitant BRAF and RAS family mutations [0.03%]
13例BRAF和RAS家族突变伴发转移性结直肠癌患者综合分析
Jigisha Srivastav,Morgan E Lehman,Joni K Evans et al.
Jigisha Srivastav et al.
Introduction: Metastatic colorectal cancer (mCRC) exhibits significant heterogeneity in molecular profiles, influencing treatment response and patient outcomes. Mutations in v-raf murine sarcoma viral oncogene homolog B1 ...
Case Report: Diagnostic pitfalls in soft tissue tumors: synovial sarcoma masquerading as venous malformation [0.03%]
个例报告：软组织肿瘤的诊断陷阱：滑膜肉瘤伪装成静脉畸形
Xuan Jiang,Li Hu,Hui Chen et al.
Xuan Jiang et al.
Introduction: Synovial sarcoma (SS) is one of the most prevalent malignant soft tissue sarcomas in children and adolescents. Pediatric populations often present with atypical features, complicating the differentiation fro...
Ferroptosis in the tumor microenvironment: mechanisms, advances, and therapeutic perspectives [0.03%]
肿瘤微环境中铁死亡机制、研究进展和治疗前景
Weijuan Gao,Jiani Tan,Chengtao Yu
Weijuan Gao
Ferroptosis is a regulated, non-apoptotic form of cell death marked by the accumulation of iron-dependent lipid peroxides. This process causes rapid rupture of the plasma membrane and the release of intracellular contents. Ferroptosis acts ...
Multi-parametric MRI-based radiomics nomogram for predicting lymphovascular space invasion in early-stage cervical adenocarcinoma [0.03%]
基于多参数MRI的影像组学列线图预测早期宫颈腺癌淋巴血管间隙侵犯
Ke-Ying Wang,Mei-Ling Xiao,Yu-Han Fang et al.
Ke-Ying Wang et al.
Purpose: To develop a magnetic resonance imaging (MRI)-based radiomics nomogram to predict lymphovascular space invasion (LVSI) status in patients with early-stage cervical adenocarcinoma (CAC). ...
Machine learning modeling of cancer treatment-related cardiac events in breast cancer: utilizing dosiomics and radiomics [0.03%]
基于剂量组学和影像组学的机器学习模型预测乳腺癌患者的癌症治疗相关心脏事件
Sefika Dincer,Muge Akmansu,Oya Akyol
Sefika Dincer
Background: Personalized medicine has transformed disease management by focusing on individual characteristics, driven by advancements in genome mapping and biomarker discoveries. ...
Case Report: Immune-mediated acute liver failure induced by tislelizumab in a patient with advanced cervical cancer [0.03%]
个例报告：替雷利珠单抗致晚期宫颈癌患者急性肝功能衰竭1例
Chaoxia Liu,Xinchun Li,Yuping Deng
Chaoxia Liu
Tislelizumab, an anti-PD-1 monoclonal antibody, is associated with immune-related hepatitis in 1.8% of cases, but reports of acute liver failure (ALF) remain exceedingly rare. We present a case of fulminant hepatitis and ALF following Tisle...
TRIM31 acts as an intermediate molecule in the process by which Snai2 impairs the proliferation of cervical cancer cells [0.03%]
TRIM31作为Snai2抑制宫颈癌细胞增殖过程中的介导分子
Nan Cui,Yanru Zhang,Yuan Zhang et al.
Nan Cui et al.
Snai2 is a transcription factor that inhibits the proliferation of cervical cancer cells and tumor growth. The expression of Snai2 inhibited the expression of β-catenin and impaired Wnt/β-catenin signaling pathway activity. The results of...
Application of low-coverage whole-genome sequencing technology in risk stratification of colorectal adenomas [0.03%]
低覆盖全基因组测序技术在结肠腺瘤风险分层的应用研究
Guo Zhili,Xue Yuyue,Yu Fang et al.
Guo Zhili et al.
Objective: The diagnosis of precancerous lesions of colorectal cancer (CRC) presents significant challenges in clinical practice. In this study, we conducted a clinical investigation using the UCAD technique after analyzi...