Enhancing antitumor immunity: the role of immune checkpoint inhibitors, anti-angiogenic therapy, and macrophage reprogramming [0.03%]
增强抗肿瘤免疫：免疫检查点抑制剂、抗血管生成疗法和巨噬细胞重编程的作用
Chong Zhang,Hua Wang,Xinying Li et al.
Chong Zhang et al.
Cancer treatment has long been hindered by the complexity of the tumor microenvironment (TME) and the mechanisms that tumors employ to evade immune detection. Recently, the combination of immune checkpoint inhibitors (ICIs) and anti-angioge...
The burden of rare cancers among adults in the Canton of Geneva, Switzerland, from 2011 to 2020 [0.03%]
2011年至2020年瑞士日内瓦州成人罕见癌症负担
Nathalie Bot,Evelyne Fournier,Marie-Laure Amram et al.
Nathalie Bot et al.
Introduction: Globally, cancer cases are expected to significantly increase due to population growth and aging, reaching 29.9 million by 2040 (+49.5% since 2022) and 32.6 million by 2045 (+63%), with countries like Switze...
Clinical characteristics and recurrence predictors of sinonasal inverted papilloma: a retrospective cohort study [0.03%]
鼻窦 inverted papilloma的临床特征和复发预测因素：一项回顾性队列研究
XiangHua Li,DongFei Wang,DeTao Yin
XiangHua Li
Objective: To investigate the clinical characteristics and predictors of postoperative recurrence in sinonasal inverted papilloma (SNIP). Methods: ...
Robotic-assisted colorectal surgery in colorectal cancer management: a narrative review of clinical efficacy and multidisciplinary integration [0.03%]
机器人辅助结直肠癌手术的临床疗效及多学科合作模式综述
Engeng Chen,Li Chen,Wei Zhang
Engeng Chen
Colorectal cancer (CRC) remains a formidable global health challenge, ranking among the most prevalent malignancies and a principal contributor to cancer-associated mortality. While traditional open surgery has historically been the corners...
Protocatechualdehyde induced tumor suppressive autophagy through AMPK/ULK1 signaling pathway in gastric cancer [0.03%]
原花青素A诱导胃癌细胞抑瘤自噬作用的实验研究
Mingming Ren,Fangqi Ma,Mengmeng Qin et al.
Mingming Ren et al.
Background: Gastric cancer (GC) is one of the primary causes of cancer-related fatalities, which requires novel treatment including traditional Chinese medicine (TCM) to prolong survival. Protocatechualdehyde (PCA), a mon...
WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer [0.03%]
WGCNA-ML-MR整合：揭示前列腺癌相关免疫基因
Jing Lv,Yuhua Zhou,Shengkai Jin et al.
Jing Lv et al.
Background: Prostate cancer is one of the most common tumors in men, with its incidence and mortality rates continuing to rise year by year. Prostate-specific antigen (PSA) is the most commonly used screening indicator, b...
Case Report: FGFR2 inhibitor resistance via PIK3CA and CDKN2A/B in an intrahepatic cholangiocarcinoma patient with FGFR2-SH3GLB1 fusion [0.03%]
个例报告：带有FGFR2-SH3GLB1融合的肝内胆管癌患者中通过PIK3CA和CDKN2A / B产生FGFR2抑制剂耐药性
Nadja Ballin,Alexander Ott,Olga Seibel-Kelemen et al.
Nadja Ballin et al.
FGFR2 fusions occur in up to 14% of patients with intrahepatic cholangiocarcinoma (iCCA) and have been considered as therapeutic target for FGFR inhibitors (FGFRi). However, response to targeted treatment may be limited due to the emergence...
Case Report: Radiological characteristics and pathological correlation analysis of extranodal Rosai-Dorfman disease of liver [0.03%]
病例报告：肝外型Rosai-Dorfman病肝脏受累的影像学及病理特征分析
Xingxing Zheng,Hongzhe Tian,Wei Li et al.
Xingxing Zheng et al.
Background: Rosai Dorfman disease (RDD), also known as sinus histiocytosis with extensive lymph node involvement, is a rare histiocytosis with unknown etiology. Liver RDD is relatively rare and is often reported in indivi...
Artificial intelligence-assisted early screening of acute promyelocytic leukaemia in blood smears: a prospective evaluation of MC-100i [0.03%]
基于血液涂片的急性早幼粒细胞白血病人工智能辅助早期筛查：MC-100i临床应用前瞻性评估
Fan Zhang,Pingjuan Liu,Jieyu Zhan et al.
Fan Zhang et al.
Objectives: Identification of abnormal promyelocytes is crucial for early diagnosis of Acute promyelocytic leukaemia (APL) and for reducing the early mortality rate of APL patients, which can be achieved by microscopic bl...
Prediction of solid pseudopapillary tumor invasiveness of the pancreas based on multiphase contrast-enhanced CT radiomics nomogram [0.03%]
基于多相强化CT影像组学列线图的胰腺实性假乳头状瘤侵袭性的预测
Dabin Ren,Liqiu Liu,Aiyun Sun et al.
Dabin Ren et al.
Objectives: To construct a multiphase contrast-enhanced CT-based radiomics nomogram that combines traditional CT features and radiomics signature for predicting the invasiveness of pancreatic solid pseudopapillary neoplas...