Case Report: Genomic insights into prostate adenocarcinoma transdifferentiation to carcinosarcoma due to lineage plasticity [0.03%]
病例报告:由于谱系可塑性导致前列腺腺癌转化为肉瘤癌的基因组洞察
Tomohiro Fukui,Arinobu Fukunaga,Yuki Teramoto et al.
Tomohiro Fukui et al.
In prostate cancer, it is recognized that adenocarcinoma can transdifferentiate into neuroendocrine prostate cancer (NEPC) owing to lineage plasticity; however, transdifferentiation into other histological types remains uncertain. We presen...
Case Report: Unraveling complex genomic alterations in a case of chronic lymphocytic leukemia using optical genome mapping [0.03%]
案例报道:使用光学基因组学映射技术解析慢性淋巴细胞白血病的复杂基因组改变
Leila Youssefian,Trilochan Sahoo,Jia-Chi Wang
Leila Youssefian
Chronic lymphocytic leukemia (CLL) is one of the most prevalent adult leukemias, derived from mature B-cells and exhibiting a highly heterogeneous disease course. Standard cytogenetic analysis of CLL includes FISH and karyotyping. However, ...
Endotheliopathy syndromes, TA-TMA, and SOS, are risk factors for morbidity and mortality in critically ill pediatric hematopoietic cell transplant recipients [0.03%]
内皮细胞病综合症、TA-TMA和SOS是危重病态造血干细胞移植受者发病率及死亡率的危险因素
Shivani Goel,Erin Frost,Keiko Tarquinio et al.
Shivani Goel et al.
Background: Pediatric hematopoietic cell transplant (HCT) recipients who require intensive care unit (PICU) admission historically have high mortality rates. The HCT landscape is rapidly changing with the incorporation of...
Complex skull base brain tumor resection: the role of microvascular doppler in surgical precision and outcomes [0.03%]
微血管多普勒在复杂颅底脑肿瘤外科切除术中的作用:提高手术精确度及改善患者预后
Kecheng Shen,Liang Sun,Weiwei Zhai et al.
Kecheng Shen et al.
Objective: To investigate the role of Doppler microvascular ultrasound (MVD) in skull base surgery for the intraoperative assessment and protection of arterial blood flow. ...
Evolution and hotspots in breast cancer organoid research: insights from a bibliometric and visual knowledge mapping study (2005-2024) [0.03%]
乳腺癌类器官研究的演变与热点:基于文献计量和可视化知识图谱的研究(2005-2024)
Tao Wu,BaiXin Li,Hao Lei et al.
Tao Wu et al.
Background: Breast cancer is the most common malignancy among women globally. Organoid technology has emerged as a pivotal tool in breast cancer research due to its advantages in modeling tumor heterogeneity and the micro...
Real-world efficacy and safety of inetetamab-based therapy in HER2-positive metastatic breast cancer patients with prior exposure to trastuzumab [0.03%]
治疗曲妥珠单抗耐药的HER2阳性转移性乳腺癌患者_INETE介导的ADC疗效及安全性的真实世界研究
Yangyang Duan,Tao Sun,Zhanhong Chen et al.
Yangyang Duan et al.
Background: Until now there has been no comprehensive data from extensive samples to evaluate the therapeutic potential of inetetamab in metastatic breast cancer (MBC) patients who had a history of trastuzumab treatment. ...
Case Report: A large granular cell tumor of the cervical esophagus with single cell RNA sequencing analysis [0.03%]
案例报告:带单细胞RNA测序分析的大食管颈段颗粒细胞瘤
Chengying Shao,Keyu Chen,Yanting Duan et al.
Chengying Shao et al.
Esophageal granular cell tumor (GCT) is a rare benign neurogenic tumor, however, malignant transformation has been reported. And there is no consensus on the choice of esophageal reconstruction in these patients. Therefore, the study of mar...
Correlation between MGMT methylation and the efficacy of bevacizumab in high-grade glioma [0.03%]
MGMT甲基化与贝伐单抗治疗高级别胶质瘤疗效的相关性分析
Chengrui Yan,Xuexue Bai,Chao Wu et al.
Chengrui Yan et al.
Purpose: The aim of this study is to investigate whether the therapeutic efficacy of bevacizumab (BEV) in the treatment of high-grade glioma (HGG) is associated with the methylation status of O6-methylguanine-DNA methyltr...
Case Report: Genomic insights and personalized treatment in dual primary esophageal squamous cell carcinoma and gastric adenocarcinoma [0.03%]
个例报告:双原发食管鳞癌和胃腺癌的基因组学见解和个性化治疗
Chuanwang Miao,Yaning Guo,Huili Yang et al.
Chuanwang Miao et al.
Dual primary malignancies in the upper gastrointestinal tract are rare and pose diagnostic and therapeutic challenges. This study reports a case of synchronous esophageal squamous cell carcinoma (ESCC) and gastric adenocarcinoma (GAC), high...
Correction: Curcumin inhibits colorectal cancer progression by targeting PTBP1 and CDK2-mediated pathways [0.03%]
白藜芦醇通过靶向PTBP1和CDK2介导的途径抑制结直肠癌进展
Hao Zheng,Shenglong Li,Ye Wang et al.
Hao Zheng et al.
[This corrects the article DOI: 10.3389/fonc.2025.1566889.]. Keywords: CDK2; Curcumin; PTBP1; autophagy the ...
Published Erratum
Frontiers in oncology. 2025 Sep 2:15:1659429. DOI:10.3389/fonc.2025.1659429 2025