Editorial: Metastatic hormone-sensitive prostate cancer: new therapeutic strategies to improve patient outcome [0.03%]
编辑部：转移性雄激素敏感前列腺癌：提高患者疗效的新治疗策略
Ludmilla T D Chinen,Marcus V Sadi
Ludmilla T D Chinen
A prediction model for predicting relapsed-free survival of early-stage invasive breast cancer patients with hormone receptor positive based on Ki67, HER2 and TOP2A [0.03%]
基于Ki67、HER2和TOP2A的激素受体阳性早期侵袭性乳腺癌患者复发无进展生存预测模型
Dawei Yuan,Rulan Ma,Haixia Ye et al.
Dawei Yuan et al.
Objective: The purpose of the current study was to determine the relationship between ribonucleotide reductase M1 (RRM1), topoisomerase II alpha (TOP2A), Thymidylate synthase (TYMS), class III beta-tubulin (TUBB3) and pho...
Tumor budding as an indicator of prognosis in locally advanced rectal cancer after neoadjuvant chemoradiotherapy: a systematic review and meta-analysis [0.03%]
新辅助放化疗后局部晚期直肠癌患者肿瘤芽生提示预后的系统评价和Meta分析
Azita Rafiee,Parto Nasri,Afshin Moradi et al.
Azita Rafiee et al.
Introduction: Tumor budding (TB) is recognized as a complementary prognostic factor for colorectal cancer. However, data on its impact on the survival of patients undergoing neoadjuvant chemoradiotherapy (nCRT) remain lim...
Adjuvant systemic therapy in early breast cancer and results of a prospective observational multicenter BRIDE study: patients outcome and adherence to guidelines in cancer clinical practice [0.03%]
早期乳腺癌的辅助系统治疗及前瞻性多中心BRIDE研究的结果：临床实践中的患者预后和对指南的依从性
Stefania Gori,Alessandra Fabi,Catia Angiolini et al.
Stefania Gori et al.
Introduction: Evaluation of every breast cancer (BC) patient by multidisciplinary team and application of guidelines are very important to ensure the best treatment and achieve the best outcome. ...
Anlotinib-associated pulmonary embolism in brainstem glioblastoma treatment: a case report [0.03%]
安罗替尼致脑干胶质瘤治疗中肺栓塞一例报告
Jia-Lan Zhao,Yong-Li Zhang,Ke-Jun Qu et al.
Jia-Lan Zhao et al.
Background: Glioblastoma (GBM) is the most common and aggressive primary brain malignancy in adults. Diagnosis primarily relies on imaging techniques like CT scan and MRI, while pathological biopsy remains the diagnostic ...
Case Report: A long-term response of immunotherapy combined with anti-angiogenesis therapy in a patient with dMMR metastatic colorectal cancer after ICI failure [0.03%]
病例报告：dMMR转移性结直肠癌患者在接受ICI治疗失败后的免疫疗法联合抗血管生成疗法的长期反应
Qianwen Huang,Xiaoling Zheng,Wenshen Xu
Qianwen Huang
Background: Immune checkpoint inhibitors (ICIs) have demonstrated significant efficacy in patients with metastatic colorectal cancer (mCRC) characterized by high microsatellite instability (MSI-H) or deficient mismatch re...
Single-cell RNA sequencing in diffuse large B-cell lymphoma: tumor heterogeneity, microenvironment, resistance, and prognostic markers [0.03%]
弥漫性大B细胞淋巴瘤的单细胞RNA测序：肿瘤异质性、微环境、耐药性和预后标志物
Linwei Li,Qiwei Li,Rui Niu et al.
Linwei Li et al.
Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous malignancy with challenges in treatment resistance and relapse. Single-cell RNA sequencing (scRNA-seq) has provided important insights into tumor heterogeneity, microenvironmen...
Activation-induced cytidine deaminase in tertiary lymphoid structures: dual roles and implications in cancer prognosis [0.03%]
激活诱导胞苷脱氨酶在三级淋巴组织中的作用及意义：双重角色与癌症预后的影响
Zhuangwei Lv,Junna Jiao,Wuyang Xue et al.
Zhuangwei Lv et al.
Activation-induced cytidine deaminase (AID) serves as a critical molecular orchestrator in the germinal center (GC) reaction within secondary lymphoid organs (SLOs), driving the production of high-affinity antibodies through somatic hypermu...
Bispecific antibodies in immunotherapy for acute leukemia: latest updates from the 66th annual meeting of the American society of hematology, 2024 [0.03%]
双特异性抗体在急性白血病免疫治疗中的最新进展：来自美国血液学学会2024年年会的更新报告
Weijie Cao,Shuhan Ma,Lijie Han et al.
Weijie Cao et al.
Bispecific antibodies (BsAbs) are cutting-edge immunotherapy agents that can bind two distinct antigens or epitopes simultaneously. They hold significant potential in targeting leukemic cell markers and activating immune cells like T cells ...
The feasibility and safety of deeply inserted enema tubes for acute malignant left-hemicolon obstruction: an alternative solution in developing countries [0.03%]
重度插管灌肠治疗急性恶性左半结肠梗阻的可行性和安全性：发展中国家的替代解决方案
Xinxiang Huang,Lijuan Zheng,Huifeng Wu et al.
Xinxiang Huang et al.
Background and aims: Disposable enema kits are commonly used for bowel preparation, with the anal tube typically positioned near the rectal ampulla. This study assesses the feasibility and safety of deeply inserting an en...