High-risk extracorporeal membrane oxygenation in immunocompromised children with acute respiratory failure: a retrospective cohort study [0.03%]
免疫抑制儿童急性呼吸衰竭体外膜肺氧合治疗的回顾性队列研究
Liudmila Belevskaia,Florian von Borell,Ulrich Baumann et al.
Liudmila Belevskaia et al.
Background: Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized in pediatric patients with severe respiratory failure, extending its use to high-risk patients, including those who are immunocompromis...
Isolated relapse of multiple myeloma in the central nervous system post autologous hematopoietic stem cell transplantation: a case report and literature review [0.03%]
自体造血干细胞移植后多发性骨髓瘤中枢神经系统孤立性复发一例及相关文献复习
Ying Zhou,Qian Shen,Jie Zhang et al.
Ying Zhou et al.
This case report retrospectively evaluated the diagnosis and treatment of a multiple myeloma (MM) patient with early relapse in the central nervous system (CNS) post autologous hematopoietic stem cell transplantation (AHSCT). We also perfor...
Development and validation of machine learning model to predict early death of melanoma brain metastasis patients [0.03%]
用于预测黑色素瘤脑转移患者早期死亡的机器学习模型的开发与验证
Maierdanjiang Maihemuti,Maiheliya Kamaierjiang,Aierpati Maimaiti et al.
Maierdanjiang Maihemuti et al.
Background: Melanoma has the third highest rate of brain metastases among all cancers and is associated with poor long-term survival. This study aimed to develop machine learning models to predict early death in melanoma ...
Shaping viral immunotherapy towards cancer-targeted immunological cell death [0.03%]
塑造病毒免疫治疗向癌症靶向免疫细胞死亡方向发展
Anastasia S Isaeva,Adriana D Trujillo Yeriomenko,Esther Idota et al.
Anastasia S Isaeva et al.
Background: Oncolytic viruses (OVs) have the ability to efficiently enter, replicate within, and destroy cancer cells. This capacity to selectively target cancer cells while inducing long-term anti-tumor immune responses,...
Case Report: Improved hearing in a rare, adult IDH2-mutant brainstem astrocytoma successfully treated with radiation and temozolomide [0.03%]
个例报告：罕见成人IDH2突变脑干星形细胞瘤成功采用放疗和替莫唑胺治疗后的听力改善案例报告
Takuya Okada,Manabu Natsumeda,Hidemoto Fujiwara et al.
Takuya Okada et al.
Introduction: Brain stem gliomas harboring IDH mutations can be sensitive to temozolomide (TMZ) treatment, unlike their H3K27-altered counterparts, so distinguishing the two is essential. ...
Detecting subclinical cardiotoxicity during immune checkpoint inhibitor therapy: a combined GLS and ECG repolarization analysis [0.03%]
免疫检查点抑制剂治疗期间检测亚临床心毒性：GLS和心电图复极联合分析用于识别接受免疫检查点抑制剂治疗时出现无症状性心脏毒性的患者中具有高风险的患者群体。
Dogac Oksen,Muhammed Heja Gecit,Sukru Arslan et al.
Dogac Oksen et al.
Purpose: Immune checkpoint inhibitors (ICIs) can induce subclinical cardiac dysfunction that often goes undetected by conventional monitoring. This study evaluated whether echocardiographic global longitudinal strain (GLS...
Cell-in-cell associated lncRNA signature predicts prognosis and immunotherapy response in gastric cancer [0.03%]
细胞内细胞相关lncRNA谱预测胃癌的预后和免疫治疗反应
Junzuo Lin,Liancheng Wu,Zhengfei Zhao
Junzuo Lin
Introduction: Gastric cancer (GC) remains a leading cause of cancer mortality, necessitating robust prognostic biomarkers and personalized therapeutic strategies. ...
Association between neutrophil-lymphocyte ratio and female breast cancer: an observational study from NHANES 2001-2018 with external validation [0.03%]
基于NHANES（2001-2018）观察研究中性粒细胞淋巴细胞比值与女性乳腺癌的相关性及外部验证分析
Juan Xiong,Deju Zhang,Jing Wu et al.
Juan Xiong et al.
Background: In the 21st century, breast cancer is the most frequent malignant tumor threatening women's health. Previous research has confirmed that inflammatory response processes play key roles in tumor occurrence, deve...
Integrating deep learning and clinical characteristics for early prediction of endometrial cancer using multimodal ultrasound imaging: a multicenter study [0.03%]
基于多模态超声影像的深度学习与临床特征整合在子宫内膜癌早期预测中的应用：一项多中心研究
Cuiyan Lin,Wanming Chen,Jichuang Lai et al.
Cuiyan Lin et al.
Background: Endometrial cancer (EC) is one of the most prevalent malignancies affecting the female reproductive system. It poses significant health risks to women and imposes a substantial economic burden on healthcare sy...
Cytokine profiling identifies circulating IL-2, IL23 and sPD-L1 as prognostic biomarkers for treatment outcomes in non-small cell lung cancer patients undergoing anti-PD1 therapy [0.03%]
细胞因子谱分析鉴定出循环IL-2，IL23和sPD-L1作为抗PD1治疗非小细胞肺癌患者预后的生物标志物
Kriti Jain,Anika Goel,Deepa Mehra et al.
Kriti Jain et al.
Background: This study investigates the predictive potential of circulating cytokines for response and survival outcomes in patients with advanced non-small cell lung cancer (NSCLC) undergoing immune checkpoint inhibitor ...