A case report and literature review of rare intracranial and extracranial dual-lesion diffuse large B-cell lymphoma with heterogeneous subtypes (GCB type + ABC type) [0.03%]
Yadong Liu,Xuejuan Duan,Jinlong Liu et al.
Yadong Liu et al.
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of malignant lymphoma in adults. According to the gene expression profile, it can be classified into germinal center B-cell (GCB) type and activated B-cell (ABC) type. Cases w...
Metachronous bilateral renal cancer with immune checkpoint blockade-mediated eradication of bone metastasis: case report [0.03%]
Dimitar Metodiev,Tsvetan Borisov,Pierre-Alexis Da Costa et al.
Dimitar Metodiev et al.
Background: The immune landscape of renal cell carcinoma (RCC) is a key determinant of response to immune checkpoint inhibitors (ICIs). Yet, direct comparisons of immune infiltrates across histologic subtypes and metastat...
Oropharyngeal cancer mortality in the United States, 1999-2023: a surveillance analysis using CDC WONDER [0.03%]
Weichen Deng,Liren Cao,Zhihai Li
Weichen Deng
Background: Oropharyngeal cancer (OPC) is a major head and neck cancer subtype with shifting U.S. epidemiology. We performed a surveillance-style analysis of OPC mortality trends and demographic/geographic disparities, 19...
Dao-Rong Hong,Chun-Yan Huang
Dao-Rong Hong
Breast cancer molecular subtyping (luminal A, luminal B, HER2-enriched, and triple-negative) guides systemic therapy selection and prognostication, yet is still determined primarily by invasive tissue sampling. Over the last decade, ultraso...
Case Report: hidradenocarcinoma presenting with lymph node metastasis: a diagnostic challenge and the pivotal role of morphology [0.03%]
Lun Li,Lidi Tian,Tao Wang
Lun Li
Hidradenocarcinoma (HAC) is a rare malignant sweat gland tumor. When presenting with lymph node metastasis and an occult primary lesion, diagnosis is often significantly delayed. We report a case of a 58-year-old man with right axillary lym...
Lin Zhou,Jiakang Jiang
Lin Zhou
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality, prompting significant advancements in therapeutic and precision medicine. Recent innovations include antibody-drug conjugates (ADCs) such as TROP-2-targ...
Global disparities in access to diagnostics and therapies for advanced non-small cell lung cancer: from discovery to delivery - a review [0.03%]
Lea Ruge,Malte Verheyen,Felix John et al.
Lea Ruge et al.
Advanced non-small cell lung cancer (NSCLC) has undergone a profound transformation over the past two decades through the integration of molecular diagnostics, targeted therapies, and immunotherapy into clinical practice. Despite these adva...
Dong Zeng,Rong Wang,Zhen Liu et al.
Dong Zeng et al.
Poorly differentiated thyroid carcinoma (PDTC) is a rare and highly malignant tumor. To date, there have been very few case reports on PTCD, so its treatment methods remain controversial and require more experience. The island-like, solid-l...
Tamoxifen-induced neutropenia and leukopenia in a breast cancer patient: a case report and literature review [0.03%]
Cheng Liu,Fadong Xu,Qinglai Liu
Cheng Liu
Background: Tamoxifen is a cornerstone of endocrine therapy for hormone receptor-positive breast cancer. While its common side effects are well-documented, severe hematological toxicities such as neutropenia and leukopeni...
Efficacy of PD-1/PD-L1 inhibitors combined with multi-targeted anti-angiogenic TKIs in advanced or metastatic NSCLC: A meta-analysis based on RCTs [0.03%]
Zeqi Tang,Xiaoming Zhang,Zhanqi Sun et al.
Zeqi Tang et al.
Background: The efficacy of combining programmed cell death protein-1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors with multi-targeted anti-angiogenic tyrosine kinase inhibitors (TKIs) in advanced or metastatic non...