Evexomostat (SDX-7320), a methionine aminopeptidase type 2 inhibitor, stimulates weight loss and inhibits obesity-accelerated tumor growth [0.03%]
methionine aminopeptidase类型2抑制剂evexomostat（SDX-7320）促进体重减轻并抑制肥胖加速的肿瘤生长
Peter Cornelius,Benjamin A Mayes,Andrew J Dannenberg et al.
Peter Cornelius et al.
Obesity and diabetes are associated with worse prognosis for numerous malignancies. Both insulin resistance and altered levels of adipokines may explain the link between obesity and tumor progression. In preclinical models, METAP2 inhibitor...
Case Report: A patient with metastatic fumarate hydratase-deficient renal cell carcinoma associated with leiomyomatosis: real-world clinical insights on systemic therapy and liver-directed SBRT [0.03%]
个例报告：与平滑肌瘤病相关的富马酸水合酶缺陷型肾细胞癌转移患者的系统治疗和肝脏导向立体定向体放射治疗（SBRT）的临床体会
Huili James Chong,Alastair Murray,Kwang Jeat Chong
Huili James Chong
Fumarate hydratase-deficient renal cell carcinoma is a rare type of renal cell carcinoma often associated with hereditary leiomyomatosis and renal cell carcinoma syndrome. These tumors tend to exhibit an aggressive behavior and metastasize ...
Progressive multifocal leukoencephalopathy as the initial manifestation of relapsed lymphoma: a case report [0.03%]
复发淋巴瘤的初始表现为进行性多灶性白质脑病一例报告
Shi Chen,Haitian Nan,Junjie Li
Shi Chen
Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal demyelinating disease of the central nervous system (CNS) caused by the reactivation of the JC polyomavirus (JCPyV). While PML is a known complication of hematologic...
Correction: Improving the therapeutic efficacy of sorafenib for hepatocellular carcinoma by repurposing disulfiram [0.03%]
纠正：通过重新定位硫胺来改善索拉非尼治疗肝细胞癌的疗效
Gong Zhang,Yufeng Wang,Bryan C Fuchs et al.
Gong Zhang et al.
[This corrects the article DOI: 10.3389/fonc.2022.913736.]. Keywords: ERK pathway; copper; disulfiram; hepat...
Published Erratum
Frontiers in oncology. 2026 Feb 18:16:1772315. DOI:10.3389/fonc.2026.1772315 2026
Next-generation sequencing for DLBCL patients with early failure after frontline R-CHOP chemo-immunotherapy [0.03%]
一线利妥昔单抗-CVP治疗失败的DLBCL患者的下一代测序检测分析
Liu Shi,Xiaohua Liu,Jing Wang et al.
Liu Shi et al.
Background: Early failure less than 12 months (POD12) of frontline R-CHOP chemo-immunotherapy in very poor outcomes and requires alternative therapy in patients with Diffuse large B-cell lymphoma (DLBCL). ...
Clinicopathological and molecular features of gynecologic perivascular epithelioid cell tumors: a single-center study [0.03%]
妇科血管周上皮样细胞肿瘤的临床病理和分子特征：单中心研究
Heng Li,Xiaoteng Sun,Zhihui Hou et al.
Heng Li et al.
Background: Perivascular epithelioid cell tumors (PEComas) are rare neoplasms characterized by the expression of both melanocytic and myoid markers. Gynecologic PEComa may show overlapping with smooth muscle tumors and ot...
18F-FDG PET/CT-derived parameters for differentiating colorectal carcinoma from adenoma [0.03%]
18F-FDG PET/CT参数在结直肠癌与腺瘤鉴别中的价值
Ting Li,Junhu Wang,Yun Zhang
Ting Li
Objective: The aim of this study is to evaluate the ability of 18F-FDG PET/CT-derived parameters to differentiate between colorectal cancer and adenoma. M...
Case report and literature review: Golidocitinib as a potential treatment for monomorphic epitheliotropic intestinal T-cell lymphoma [0.03%]
个例报告及文献回顾：戈利西妥单抗可能是形态单一上皮细胞亲嗜性肠T细胞淋巴瘤的治疗药物
Xinlong Xu,Chang Dong,Jiashuo Guo et al.
Xinlong Xu et al.
Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a rare type of non-Hodgkin lymphoma and a highly aggressive malignancy with a median overall survival of 7 months. Meanwhile, owing to the complex and confusing symptoms incl...
Study on the prediction of postoperative metastasis in renal cancer using perirenal fat CT radiomics combined with clinical features [0.03%]
基于临床特征联合肾周脂肪CT影像组学的肾癌术后转移预测研究
Jing Zhou,Tiantian Zhou,Yuqiong Yang et al.
Jing Zhou et al.
Background: This study aims to develop a combined predictive model for predicting postoperative metastasis risk in renal cell carcinoma (RCC) patients based on preoperative arterial-phase Computed tomography(CT) images, i...
Anup S Pathania,Natalia A Osna
Anup S Pathania
Viral hepatitis is an infection caused by hepatotropic viruses that leads to liver inflammation and may progress from a prolonged asymptomatic phase to decompensated liver disease. Among the main types, hepatitis A (HAV), B (HBV), and C(HCV...