Advanced dose calculation strategies for clinical linear accelerators: a systematic review [0.03%]
医用直线加速器剂量计算的高级策略：系统综述
Ali H D Alshehri,Abdulrahman Al Mopti
Ali H D Alshehri
Background: Delivering accurate radiation doses in heterogeneous tissues is critical in radiotherapy, yet conventional algorithms often lose accuracy in complex scenarios. Monte Carlo (MC) simulation offers a high-fidelit...
Case report of an appendiceal neuroendocrine tumor (carcinoid) combined with a parovarian cyst in an adolescent [0.03%]
青少年阑尾神经内分泌肿瘤（类癌）合并副卵巢囊肿病例报告
Yali Tian,Ying Wu,Fang Hao et al.
Yali Tian et al.
Background: Appendiceal neuroendocrine tumors (NETs) are rare in adolescents and typically an incidental finding, making preoperative diagnosis difficult. We report an exceptional case of an appendiceal NET coexisting wit...
The meat processing exposome in Africa: integrating traditional culinary practices, environmental co-exposures, and cancer prevention strategies [0.03%]
非洲的肉类加工暴露组：整合传统烹饪方法、环境共暴露和癌症预防策略
Eugene Jamot Ndebia,Gabriel Tchuente Kamsu
Eugene Jamot Ndebia
Dietary exposure to carcinogenic compounds generated during meat processing represents a critical yet underexplored component of the African cancer exposome. Traditional high-temperature cooking methods, including smoking, grilling (braai),...
Efficacy and safety of high-intensity focused ultrasound versus cryoablation for breast fibroadenomas: a systematic review and meta-analysis [0.03%]
高强度聚焦超声与乳腺纤维瘤冷冻消融治疗的有效性和安全性系统评价和meta分析
YuanFeng Zhao,Jian Sun,Shuai Lin
YuanFeng Zhao
Methods: Up to October 2025, a systematic search was conducted in PubMed, Embase, and Web of Science. Eligible studies included patients with confirmed breast fibroadenoma treated with high-intensity focused ultrasound (H...
From molecular crosstalk to precision therapy: targeting ferroptosis and cuproptosis in oral squamous cell carcinoma [0.03%]
从分子相互作用到精准治疗：靶向口腔鳞状细胞癌的铁死亡和铜死亡
Xikun Ma,Yiqi Chen,Huaqing Mai et al.
Xikun Ma et al.
Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumors in the head and neck region, where conventional therapies have limited efficacy and patients have poor prognosis. As newly identified metal ion-dependent program...
Comparative molecular analysis of colorectal cancer in Saudi Arabia: distinct genetic alterations and clinical features [0.03%]
沙特阿拉伯结直肠癌的分子比较分析：独特的基因改变和临床特征
Maha-Hamadien Abdulla,Jumanah Yousef Alshenaifi,Mansoor-Ali Vaali-Mohammed et al.
Maha-Hamadien Abdulla et al.
Purpose: Globally, colorectal cancer (CRC) stands as the third most common type of cancer, a ranking that has remained consistent over recent years. However, the scenario diverges in Saudi Arabia, where CRC ascends to the...
Long-term survival in metastatic abdominal Ewing sarcoma with gastric serosal involvement following first-line irinotecan plus cisplatin: a case report [0.03%]
伊立替康联合顺铂新辅助化疗治疗胃浆膜受侵的转移性腹腔尤因肉瘤的长期生存：一例报告
Lianhua Ji,Yutong Li,Xiaofeng Chen et al.
Lianhua Ji et al.
Background: Abdominal primary Ewing sarcoma (ES) is extremely rare and carries a dismal prognosis when metastatic. First-line therapy typically involves multi-agent regimens like VDC/IE, with irinotecan-based combinations...
Silencing TMED2 suppresses cell growth and tumor progression in diffuse large B-cell lymphoma via inducing G0/G1 cell cycle arrest [0.03%]
沉默TMED2通过诱导G0 / G1细胞周期停滞抑制弥漫性大B细胞淋巴瘤的细胞生长和肿瘤进展
Wei Qian,Mingzhen Yang
Wei Qian
Background: Transmembrane Emp24 Domain Containing 2 (TMED2) is involved in various cancers, but its role in diffuse large B-cell lymphoma (DLBCL) remains unclear. This study investigated TMED2's expression, biological fun...
Glucocorticoids as adjunctive therapy for severe myelosuppression induced by combined immune checkpoint inhibitor and chemotherapy: a case report and literature review [0.03%]
糖皮质激素作为免疫检查点抑制剂联合化疗引起的重度骨髓抑制的辅助治疗：一例报告及文献回顾
Shimin Tang,Na Li,Ji Ma
Shimin Tang
Objective: We conducted a retrospective case series of two lung cancer patients treated at Suining Central Hospital (January-March 2025) who developed severe myelosuppression after immune checkpoint inhibitor (ICI) -chemo...
Adherence to endocrine therapy and survival outcomes in hormone receptor-positive breast cancer [0.03%]
激素受体阳性乳腺癌患者内分泌治疗的依从性及其对预后的影响
Xiao Ju,Ke Han
Xiao Ju
Objective: To evaluate the association between adherence to adjuvant endocrine therapy and overall survival as well as breast cancer-specific survival in patients with hormone receptor-positive breast cancer, to character...