Acidic microenvironment-induced LAMC2 expression promotes proliferation, migration, and pathway regulation in non-small cell lung cancer cells [0.03%]
酸性微环境通过诱导LAMC2表达促进非小细胞肺癌的增殖、迁移及信号转导途径调节
Lu Wang,Dengliang Huang,Yaogang Zhang et al.
Lu Wang et al.
Objective: This study aims to investigate the regulatory mechanism by which the acidic microenvironment modulates LAMC2 expression in non-small cell lung cancer (NSCLC) and to elucidate its roles in tumor cell proliferati...
Abnormal nutritional status determined by the controlling nutritional status score is associated with lymph node metastasis in female patients with breast cancer, but Naples prognostic score not [0.03%]
由营养状况评定量表确定的异常营养状态与乳腺癌女性患者的淋巴结转移有关，但那不勒斯预后评分无关
Weihua Wen,Litao Jin,Yuyang Yang et al.
Weihua Wen et al.
Background: Nutritional status and inflammatory status play crucial role in the occurrence and development of cancer. This study aims to explore the relationship between abnormal nutritional status determined by the Contr...
Prediction of lymph node metastasis in cN0 papillary thyroid carcinoma using a random forest-based radiomics model integrating contrast-enhanced ultrasound and clinical data [0.03%]
基于随机森林的影像组学模型结合增强超声及临床资料预测cN0期乳头状甲状腺癌淋巴结转移
Shasha Yuan,Di Tang,Lei Han et al.
Shasha Yuan et al.
Objectives: The aim of this study was to evaluate a radiomics model integrating contrast-enhanced ultrasound (CEUS) features and clinical indicators for predicting lymph node metastasis (LNM) in patients with papillary th...
Symptom severity clusters in myeloproliferative neoplasms are unrelated to disease phenotype: results from a multicenter survey of the East German study group for hematology and oncology (OSHO #97) [0.03%]
伊朗籍患者骨髓增生性肿瘤症状严重程度聚类与疾病表型无关：东德血液病及肿瘤学研究组多中心调查结果(OSHO97)
Sabine Felser,Maximilian Koeppel,Rea Kuehl et al.
Sabine Felser et al.
Background: Myeloproliferative neoplasms (MPNs) comprise a heterogeneous group of clonal hematopoietic stem cell disorders with distinct molecular pathogenesis and treatment strategies. Across all MPN subtypes, patients e...
Generation of deep learning based virtual contrast-enhanced CT images from noncontrast CT images for target volume delineation in cervical cancer radiotherapy [0.03%]
基于深度学习的虚拟造影CT图像生成方法及其在宫颈癌放射治疗靶区勾画中的应用研究
Yukai Chen,Hongling Xie,Shichun Wang et al.
Yukai Chen et al.
Purpose: This study sought to develop an nnTransUNet model for synthesizing virtual contrast-enhanced CT from non-contrast CT, and to evaluate its feasibility for target volume delineation in cervical cancer radiotherapy ...
Spatial heterogeneity of the association between fine particulate matter and lung cancer incidence in Hebei Province [0.03%]
河北省细颗粒物与肺癌发病关联的空间异质性分析
Ze Liu,Chang Yan,Zhiqiang Yan et al.
Ze Liu et al.
Background: Long-term exposure to particulate matter (PM2.5) can increase the population's risk of lung cancer incidence. This study aims to further analyze the spatial heterogeneity in the association between PM2.5 and l...
PD-1 inhibitor-induced systemic sclerosis with early interstitial lung disease and autoimmune thyroiditis in advanced gastric cancer: a case report and literature review [0.03%]
抗PD-1诱导的系统性硬化病伴早期间质性肺疾病和自身免疫甲状腺炎一例及文献复习
Qi Lyu,Xiquan Xu,Wanyue She et al.
Qi Lyu et al.
Immune checkpoint inhibitors (ICIs) have revolutionized anti-tumor therapy, yet their use is increasingly complicated by immune-related adverse events (irAEs). We present a rare case in which sequential administration of two PD-1 inhibitors...
Risk factors associated with cerebellar mutism syndrome and late postoperative hydrocephalus following pediatric posterior fossa medulloblastoma surgery [0.03%]
儿童小脑髓母细胞瘤术后共济失调性失语综合症及术后晚期脑积水的相关危险因素分析
Jingxi Du,Fan Chen,Zhen Wang et al.
Jingxi Du et al.
Objective: To investigate the risk factors for postoperative complications in pediatric patients with posterior cranial fossa medulloblastoma(MB). Methods...
Integration of network toxicology and transcriptomics reveals the potential regulatory role of the 'Arecoline/4-NQO-AKT1-m6A factor' axis in the development of OSCC [0.03%]
网络毒理学与转录组学的整合揭示了阿雷可林/4-硝基喹啉-N-氧化物-AKT1-m6A轴在口腔鳞癌发生发展中的潜在调控作用
Yongle Qiu,Yamei Wang,Jiahong Zhao et al.
Yongle Qiu et al.
Objective: The synergistic carcinogenic effect of areca nut chewing and tobacco exposure is a major risk factor for oral squamous cell carcinoma (OSCC). However, the molecular mechanisms, particularly related to N6-methyl...
Effects of photobiomodulation therapy on upper limb lymphedema secondary to breast cancer: a systematic review and meta-analysis [0.03%]
光生物调节治疗对乳腺癌继发上肢淋巴水肿的影响：系统评价和meta分析
Chenjie Qian,Zixin He,Chunhua Liu et al.
Chenjie Qian et al.
Background: Breast cancer-related lymphedema (BCRL) is a common complication that impairs function and quality of life. The effectiveness of photobiomodulation (PBM) therapy remains unclear, necessitating a systematic rev...