The implication of aberrant NRF2 activation in management of female cancers [0.03%]
异常激活的NRF2在女性癌症管理中的意义探究
Mankgopo Kgatle,Saidon Mbambara,Olalekan Fadebi et al.
Mankgopo Kgatle et al.
The overactivation of NRF2 (Nuclear factor erythroid 2-related factor 2) in female malignancies is an emerging field of study with significant implications for treatment efficacy. NRF2 plays a pivotal role in managing inflammation-induced o...
Oxaliplatin versus irinotecan as first-line therapy in metastatic colorectal cancer with prior adjuvant treatment: a retrospective study on efficacy, sequential therapy, and the impact of thrombocytopenia [0.03%]
奥沙利铂与伊立替康作为既往接受过辅助治疗的转移性结直肠癌一线治疗的有效性和序贯治疗：一项回顾性研究及血小板减少的影响
Han Shan,Shuohan Huang,Changming Zhou et al.
Han Shan et al.
Background: The comparative efficacy of oxaliplatin versus irinotecan as first-line therapy in mCRC patients with prior adjuvant treatment remains unclear. ...
Reconstruction of a massive abdominal wall defect after colon cancer surgery using bilateral thoracoabdominal flaps and a vertical rectus abdominis myocutaneous flap: a case report [0.03%]
结肠癌术后应用双侧胸腹皮瓣和竖直腹壁肌皮瓣修复巨大腹壁缺损的病例报告
Shuo Li,Zhi Zhang,Chongqing Gao et al.
Shuo Li et al.
A 35-year-old woman presented with a local recurrence at the stoma site three months after Hartmann's procedure for sigmoid colon cancer. In the subsequent months, the tumor exhibited rapid progression, with direct invasion into the abdomin...
Overcoming diagnostic pitfalls in primary gastric squamous cell carcinoma: the imperative of adequate sampling in an elderly female patient, case report [0.03%]
老年女性原发性胃鳞状细胞癌诊断陷阱及充分取材必要性病例报告
Wanhui Dong,Li Cheng,Jing Xu et al.
Wanhui Dong et al.
Objective: To report the diagnosis and treatment of a rare case of primary gastric squamous cell carcinoma (PGSCC) in an elderly female, and to explore the diagnostic pitfalls and individualized treatment strategies. ...
Impact of clinical and dosimetric factors on severe oral mucositis in head and neck cancer: insights from a phase II clinical trial [0.03%]
一项II期临床试验：头颈部肿瘤患者严重口腔黏膜炎的临床和剂量学因素的影响及新的认识
Alicia Lozano-Borbalas,Olivia Jordi-Ollero,Jordi Marruecos et al.
Alicia Lozano-Borbalas et al.
Introduction: Oral mucositis (OM) is the most common acute treatment-limiting adverse effect in patients with head and neck cancer (HNC), particularly following concomitant radiotherapy (RT) and systemic therapy. However,...
Correction: Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle [0.03%]
纠正：Lathyrol通过改变TGF-β / Smad途径成分的表达并进而影响细胞周期来抑制Renca细胞增殖
Shengyou Song,Yalin Song
Shengyou Song
[This corrects the article DOI: 10.3389/fonc.2025.1629962.]. Keywords: TGF-β/Smad signalingsmad signal path...
Published Erratum
Frontiers in oncology. 2025 Nov 17:15:1725790. DOI:10.3389/fonc.2025.1725790 2025
Clinical management and prognostic determinants of gallbladder neuroendocrine carcinoma: a single-institutional analysis of 31 cases [0.03%]
31例胆囊神经内分泌癌临床特点及预后因素分析
Yuting Luo,Yu Zhou,Gang Wang et al.
Yuting Luo et al.
Background: Gallbladder neuroendocrine carcinoma (GB-NEC) is an exceptionally rare and highly aggressive malignancy, accounting for only 0.2% of gastrointestinal neuroendocrine neoplasms and 2.3% of gallbladder cancers. D...
Immunotherapy monotherapy for patients with recurrent nonmetastatic larynx cancer who refuse salvage total laryngectomy [0.03%]
拒绝挽救性全喉切除术的复发性非转移声门癌患者的免疫单药治疗
Courtney Brooke Shires,Merry E Sebelik
Courtney Brooke Shires
Objectives/hypothesis: Total laryngectomy has traditionally been recommended for patients with recurrent larynx cancer after radiation or chemoradiation. Some patients refuse salvage surgery. Historically, these patients ...
Developing a prognostic stratification model based on glutathione metabolism in thyroid cancer and validating RRM2's tumor-promoting role [0.03%]
基于甲状腺癌谷胱甘肽代谢的预后分层模型的建立及RRM2促肿瘤作用的验证
Wei Ao,Teng-Hong Liu,De-Tao Yin et al.
Wei Ao et al.
Introduction: Glutathione (GSH), the most abundant antioxidant in cells, acts as free radical scavenger and detoxifying agent. Elevation of GSH metabolism protects tumor from damage of oxidant and even promotes tumor prog...
Spatially fractionated radiotherapy combined with CapeOX and bevacizumab for postoperative pulmonary metastasis from urachal carcinoma: a case report [0.03%]
空间分割放射治疗联合卡培他滨+奥沙利铂和贝伐单抗治疗尿囊癌肺转移术后复发1例报告
Jian Fang,Aixin Wang,Quan Yao et al.
Jian Fang et al.
Urachal carcinoma is a rare and aggressive malignancy with limited treatment options, particularly in the metastatic setting. Standardized therapeutic protocols are lacking. This case report describes a 62-year-old female patient who develo...