Relationship between myeloid skewing and colorectal cancer risk in the Framingham Heart Study [0.03%]
Lisa Ek Orloff,Michael De Lisio
Lisa Ek Orloff
Introduction: Differential regulation of myelopoiesis may contribute to divergent colorectal cancer (CRC) risk profiles associated with obesity and physical activity; however, this relationship has not been examined in hu...
Phase II study of magrolimab combined with docetaxel in previously treated metastatic advanced solid tumors [0.03%]
Antoine Italiano,Teresa García Manrique,Enrique Grande Pulido et al.
Antoine Italiano et al.
Background: Novel treatments are needed to improve the poor prognosis of metastatic cancers. The ELEVATE Lung&UC study evaluated magrolimab plus docetaxel in patients with metastatic non-small cell lung cancer (mNSCLC), m...
Plasma expression of long non-coding RNA GAS5 and its prognostic significance in newly diagnosed multiple myeloma [0.03%]
Anica Pravdic Divac,Natasa Tosic,Zorica Cvetkovic et al.
Anica Pravdic Divac et al.
Introduction: Long non-coding RNAs (lncRNAs) participate in pathogenesis, progression and therapy resistance in multiple myeloma (MM). Growth Arrest-Specific 5 (GAS5) is a lncRNA with a role in proliferation, invasion and...
Personalized swallowing rehabilitation program for post-surgical dysphagia in oral cancer patients: a randomized controlled trial [0.03%]
Yanhong Zhang,Hua Chen,Jie Zhou et al.
Yanhong Zhang et al.
Background: Dysphagia following oral cancer ablative surgery with free flap reconstruction significantly impairs quality of life, yet personalized rehabilitation approaches remain understudied. This randomized controlled ...
Front-line treatment approaches in multiple myeloma: real-world data from a community-based oncology network [0.03%]
R Steve Paulson,Santosh Gautam,Rohan Medhekar et al.
R Steve Paulson et al.
Background: The front-line (1L) treatment landscape for newly diagnosed multiple myeloma (NDMM) is rapidly evolving with guidelines endorsing triplet and quadruplet regimens as new standard-of-care. Despite this, real-wor...
Gut microbiome restructuring in laryngeal squamous cell carcinoma identifies stable microbial biomarkers with diagnostic potential [0.03%]
Jiaming Zhang,Jingtai Zhi,Jianxin Li et al.
Jiaming Zhang et al.
Background: Alterations in the gut microbiota have been reported in various malignancies, but its role in laryngeal squamous cell carcinoma (LSCC) remains unclear. ...
Ultrasound-guided microwave ablation for small thyroid nodules with RAS mutation: a pilot study [0.03%]
Fengyun Cheng,Yujiang Li,Ruixue Huang et al.
Fengyun Cheng et al.
Objective: The clinical management of RAS-mutated nodules faces significant challenges. This study aimed to explore the efficacy of microwave ablation (MWA) for the treatment of thyroid nodules ≤ 2 cm with isolated RAS g...
Cuiping Mao,Xiaohe Hao
Cuiping Mao
Background: Diffuse Large B-Cell Lymphoma (DLBCL) represents the most prevalent subtype of Non-Hodgkin Lymphoma (NHL). Cryoglobulinemia results from reversible precipitation of serum immunoglobulin complexes at low temper...
VA/VHAG alternating consolidation regimen combined with umbilical cord blood and mesenchymal stem cell infusion for the treatment of high-risk MDS patients who are unfit for transplantation: a case report and literature review [0.03%]
Qixin Sun,Zhenzhen Wen,Yanying Ling et al.
Qixin Sun et al.
The only treatment option for high-risk MDS patients unfit for transplantation is continuous treatment with a hypomethylating agent (HMA). In this context, some new combination HMA regimens and other drugs with different mechanisms of actio...
Mengyuan Pan,Tianyi Tao,Dehui Kong et al.
Mengyuan Pan et al.
Bladder cancer (BCa) is one of the most common malignant tumors of the urinary system. Its frequent recurrence, high metastatic potential, and resistance to therapies pose major obstacles to achieving long-term patient survival. As a core f...