Multiparametric MRI-based nomogram integrating clinicopathological factors for predicting HER2 expression status in breast cancer [0.03%]
结合临床病理因素的多参数MRI列线图预测乳腺癌HER2表达状态
Yi Chen,Xiaofeng Chen,Bowen Yue et al.
Yi Chen et al.
Background: Human epidermal growth factor receptor 2 (HER2) expression in breast cancer (BC) determines the options for targeted therapy. Multiparametric MRI (mpMRI) has the potential for noninvasive HER2 status predictio...
Active surveillance or surgical resection? A survey of treatment strategies for low-risk papillary thyroid microcarcinoma in adults [0.03%]
主动监测还是手术切除？低危成人乳头状甲状腺微小癌治疗策略的调查研究
Xia Qin,Ming-Tao Chang,Qiao-Zhi Feng et al.
Xia Qin et al.
Objective: The purpose of this study was to investigate the clinical status of active monitoring [active surveillance (AS)] or surgical resection for adult low-risk papillary thyroid microcarcinoma (cT1aN0M0 PTMC) in the ...
Alectinib shows promise for the treatment of refractory ALK-positive large B-cell lymphoma: a case report [0.03%]
阿来替尼治疗难治性ALK阳性大B细胞淋巴瘤一例报告
Atheer Alsulami,Roula Almufti,Saleem Eldadah et al.
Atheer Alsulami et al.
Introduction: Anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK+ LBCL) is rare, accounts for
Case Report: Neoadjuvant chemoimmunotherapy achieving pathological complete response in two cases of stage III EGFR-mutant NSCLC with high PD-L1 expression [0.03%]
病例报告：新辅助化疗免疫治疗在II-III期EGFR突变高PD-L1表达型NSCLC中的病理完全缓解
Diming Wang,Tangbin Liu,Jian Zhao et al.
Diming Wang et al.
Resectable locally advanced EGFR-mutant non-small cell lung cancer (NSCLC) represents a distinct therapeutic challenge. Owing to an inherently immunosuppressive tumor microenvironment-frequently characterized by absence of or low PD-L1 expr...
Expert consensus from the Chinese medical association on pharmaceutical management of combined cardio-oncology physician-pharmacist clinics [0.03%]
中国医师协会心血管内科医师分会肿瘤心脏病学组药物治疗专家共识
Ziyan Lyu,Hui Huang,Yuan Bian et al.
Ziyan Lyu et al.
Comparative efficacy and safety of etoposide plus PEG-rhG-CSF versus etoposide plus G-CSF for haematopoietic stem cell mobilisation in patients with multiple myeloma and lymphoma [0.03%]
比较评价培门冬酶联合PEG-rhG-CSF与培门冬酶联合G-CSF在多发性骨髓瘤和淋巴瘤患者动员造血干细胞中的疗效及安全性研究
Yiming Zhao,Lixia Liu,Wei Qian et al.
Yiming Zhao et al.
Introduction: Efficient and safe mobilisation of haematopoietic stem cells is essential for successful autologous haematopoietic stem cell transplantation (ASCT). Although pegylated recombinant human granulocyte colony st...
The aMAP score improves discrimination of prognostic models in hepatocellular carcinoma after radiofrequency ablation [0.03%]
aMAP评分可改善射频消融后肝细胞癌患者预后模型的鉴别能力
Luchang Fan,Yiyan Zhang,Jianmin Ding et al.
Luchang Fan et al.
Purpose: The aMAP score has proven a reliable model for predicting the risk of hepatocellular carcinoma (HCC) development in patients with various types of hepatitis, but its value in predicting recurrence in HCC patients...
Cuproptosis and prostate cancer: from molecular mechanisms and microenvironment remodeling to precision therapy [0.03%]
铜死亡与前列腺癌：从分子机制和肿瘤微环境重塑到精准治疗
Zhonghao Tang,Si Shen,Chen Guo et al.
Zhonghao Tang et al.
Prostate cancer (PCa) is a leading malignancy, and progression to castration-resistant prostate cancer (CRPC) remains a central therapeutic challenge. Cuproptosis, a copper-dependent cell death mechanism first characterized in 2022, is trig...
Repurposing loratadine to induce ferroptosis and overcome multidrug resistance: preclinical evidence in KB-V-1 cells [0.03%]
洛拉替丁诱导铁死亡克服耐药的体外及体内研究证据
Nicholas Cook,Xin Li,Nathan J Bowen et al.
Nicholas Cook et al.
Background: MDR1/P-glycoprotein-mediated multidrug resistance (MDR) limits chemotherapy efficacy across many cancers. Ferroptosis, an iron-dependent regulated cell death driven by lipid peroxidation, offers a potential st...
Artificial intelligence-enabled liquid biopsy in cancer: a systematic review and meta- analysis of diagnostic performance and biological implications [0.03%]
人工智能赋能的癌症液体活检系统性回顾和诊断性能及生物意义的meta分析
Luisana Sisca,Mariam Grazia Polito,Emy Sisca et al.
Luisana Sisca et al.
Background: Liquid biopsy offers a minimally invasive approach for cancer detection and monitoring, but its diagnostic performance is often limited by low signal abundance and biological noise. Artificial intelligence (AI...