AMPs inhibit the proliferation, migration, and invasion of lung cancer via the CHRM3/PI3K/AKT and CHRM3/MAPK pathways [0.03%]
AMP通过CHRM3/PI3K/AKT和CHRM3/MAPK途径抑制肺癌的增殖、迁移和侵袭
Jun Wu,Congcong Huang,Shangning Wang et al.
Jun Wu et al.
Aims: Our previous studies indicated that the overexpression of M3 muscarinic receptor (M3R/CHRM3) is related to a poor prognosis in patients with lung cancer and that Armillaria mellea polysaccharides (AMPs) can exhibit ...
ACTivity as medicine In Oncology for Head and Neck (ACTIOHN): a feasibility study investigating a patient-centred approach to exercise for head and neck cancer patients [0.03%]
头颈肿瘤患者以病人为中心的运动干预方案的可行性研究(ACTIOHN: ACTivity as medicine In Oncology for Head and Neck)
Joanne M Patterson,Mary G Cherry,Andrew Levy et al.
Joanne M Patterson et al.
Objective: To determine the feasibility and acceptability of integrating a remote, personalised, collaborative, and flexible exercise programme into the head and neck cancer (HNC) care pathway. ...
Salidroside inhibits melanin synthesis and melanoma growth via mTOR and PI3K/Akt pathways [0.03%]
山慈菇素通过mTOR和PI3K/Akt信号通路抑制黑色素合成及黑色素瘤生长
Qi Ouyang,Shengye Tian,Hengyu Zhou et al.
Qi Ouyang et al.
Background: Melanomas are caused by the malignant transformation of melanocytes. Numerous studies have demonstrated that the tyrosol components of salidroside inhibit tyrosinase activity. The PI3K/Akt/mTOR signaling pathw...
From dysbiosis to precision therapy: decoding the gut-bladder axis in bladder carcinogenesis [0.03%]
从菌群失调到精准治疗：解码肠道-膀胱轴在膀胱癌发生中的作用
Ze-Qiang Liu,Xiao-Ying Yang,Jia-Hong Chen et al.
Ze-Qiang Liu et al.
The gut-bladder axis (GBA), a bidirectional network connecting gastrointestinal and urinary systems, has recently emerged as a pivotal focus in bladder cancer research. Beyond conventional risk factors, gut dysbiosis, aberrant microbial met...
Guofang Chen,Tingyi Wei,Ao Huang et al.
Guofang Chen et al.
Background: Stem cell plasticity plays key roles in mammalian organogenesis, tissue homeostasis, and carcinogenesis. Given its tolerance to anti-tumor therapy and its promotion on immunosuppressive microenvironment, cance...
Case Report: Concurrent neurofibromatosis type 1 with papillary thyroid carcinoma and gastrointestinal stromal tumor [0.03%]
神经纤维瘤病1型合并甲状腺乳头状癌和胃肠间质瘤病例报告
Ruba Dweik,Jana Faroun,Rita Yacoub et al.
Ruba Dweik et al.
Neurofibromatosis type 1 (NF1) is a genetic disorder characterized by benign tumors such as neurofibromas and café-au-lait spots, with affected individuals at increased risk for malignant tumors, including gastrointestinal stromal tumors (...
Global research trends and hotspots in prognostic prediction models for pancreatic cancer: a bibliometric analysis [0.03%]
基于文献计量的国际胰腺癌预后预测模型研究趋势及热点分析
Siyuan Ouyang,Jing Zhang,Fuyao Liu et al.
Siyuan Ouyang et al.
Background: Pancreatic cancer is a highly aggressive malignancy of the digestive system, characterized by insidious onset and rapid progression. Most cases are diagnosed at advanced stages, complicating surgical resection...
UnetTransCNN: integrating transformers with convolutional neural networks for enhanced medical image segmentation [0.03%]
基于Transformer和卷积神经网络的医学图像分割方法
Yi-Hang Xie,Bo-Song Huang,Fan Li
Yi-Hang Xie
Introduction: Accurate segmentation of 3D medical images is crucial for clinical diagnosis and treatment planning. Traditional CNN-based methods effectively capture local features but struggle with modeling global context...
Deep learning-assisted diagnosis of liver tumors using non-contrast magnetic resonance imaging: a multicenter study [0.03%]
基于非对比磁共振影像的肝脏肿瘤深度学习辅助诊断方法研究：多中心研究
Shihui Zhen,Peng Zhang,Hanxiao Huang et al.
Shihui Zhen et al.
Objectives: Non-contrast MRI(NC-MRI) is an attractive option for liver tumors screening and follow-up. This study aims to develop and validate a deep convolutional neural network for the classification of liver lesions us...
Mapping the immunological landscape and emerging immunotherapeutic strategies in cervical cancer: a comprehensive review [0.03%]
宫颈癌免疫图谱和新兴免疫治疗策略的全面综述
Xinyi Zhang,Wenyang Nie,Wenwen Shao et al.
Xinyi Zhang et al.
Cervical cancer continues to pose a considerable global health challenge, especially in low- and middle-income nations, although progress in screening and vaccine efforts. In recent years, immunotherapy has emerged as a promising treatment ...