The association of molecular classification with fertility-sparing treatment of atypical endometrial hyperplasia and endometrial cancer: a retrospective study [0.03%]
分子分型与子宫内膜非典型增生和子宫内膜癌保留生育功能治疗相关性的研究：一项回顾性研究
Yuanyuan Wang,Tianjiao Lai,Danxia Chu et al.
Yuanyuan Wang et al.
Background: To evaluate whether molecular classification was associated with treatment response and recurrence in women with atypical endometrial hyperplasia (AEH) or early-stage endometrial cancer (EC) treated with proge...
The TFRC as a prognostic biomarker and potential therapeutic target in cervical cancer: a preliminary study [0.03%]
TFRC作为宫颈癌预后生物标志物和潜在治疗靶点的初步研究
Jing Wang,Wen An,Ziyao Pang et al.
Jing Wang et al.
Background: Early detection and treatment of CIN or early-stage cervical cancer lead to better clinical outcomes compared to treating advanced-stage patients. Thus, specific biomarkers for the diagnosis and prognosis of C...
Tumor-associated macrophages correlate with better outcome in SHH medulloblastoma [0.03%]
肿瘤相关巨噬细胞与SHH型髓母细胞瘤较好预后相关
Jin Zhang,Shuting Li,Yuan Wang et al.
Jin Zhang et al.
Objective: Tumor-associated macrophages (TAMs) constitute a significant proportion of the immune cell population within brain tumors. The polarization of macrophages exerts an important influence on the tumor microenviron...
Validation of machine learning-based models to predict and explain the risk of ovarian cancer: a multicentric study on BRCA-mutated patients undergoing risk-reducing salpingo-oophorectomy [0.03%]
基于机器学习的模型预测和解释BRCA突变受试者卵巢癌风险的多中心研究：接受风险降低型输卵管-卵巢切除术患者中的验证性研究
Vera Loizzi,Maria Colomba Comes,Francesca Arezzo et al.
Vera Loizzi et al.
Objective: BRCA-mutated women are recommended to undergo bilateral risk-reducing salpingo-oophorectomy (RRSO) after childbearing, due to the lack of effective methods that could be able to early detect the occurrence of o...
SNRPB2: a prognostic biomarker and oncogenic driver in esophageal cancer via β-catenin/c-Myc signaling [0.03%]
SNRPB2通过β-连环蛋白/c-Myc信号通路作为预后生物标志物和致癌驱动基因在食管癌中的作用
Jiaqian Bao,Xiong Tian,Yixiao Pan et al.
Jiaqian Bao et al.
Background: The SNRPB2 gene encodes Small Nuclear Ribonucleoprotein Polypeptide B2, a crucial component involved in RNA splicing processes. While SNRPB2 dysregulation has been observed in various cancers, its role in esop...
Down-regulation of miR-125b by HPV16 E6 might promote cervical cancer progression through TAZ/TEAD [0.03%]
HPV16 E6下调miR-125b可能通过TAZ/TEAD促进宫颈癌进展
Yongli Hou,Lili Zhang,Wenhao Wang et al.
Yongli Hou et al.
Background: Abnormal gene expression due to the dysregulation of microRNAs (miRNAs) often occurred in the initiation or progression of cancers. In this attempt, we investigate whether miR-125b regulates biological behavio...
Cost-effectiveness of companion BRCA testing and adjuvant olaparib treatment in patients with BRCA-mutated high-risk HER2-negative early breast cancer [0.03%]
BRCA突变高危HER2阴性早期乳腺癌患者伴行BRCA检测和辅助使用奥拉帕利的成本效益分析
Silviya Nikolova,Wenkang Ma,Gurdeep S Sagoo et al.
Silviya Nikolova et al.
Background and objective: As the healthcare industry evolves towards precision medicine, methods to assess the value of integrating companion diagnostics in clinical practice through adequate reimbursement levels are beco...
Ryan D Castle,James Marzolf,Miranda Morris et al.
Ryan D Castle et al.
Background: Growing bodies of evidence suggest that cannabis may play a significant role in both oncological palliative care and as a direct anticarcinogenic agent, but classification as a Schedule I substance has complic...
Methodological and reporting quality of machine learning studies on cancer diagnosis, treatment, and prognosis [0.03%]
机器学习在癌症诊断、治疗和预后研究中的方法质量和报告质量
Aref Smiley,David Villarreal-Zegarra,C Mahony Reategui-Rivera et al.
Aref Smiley et al.
This study aimed to evaluate the quality and transparency of reporting in studies using machine learning (ML) in oncology, focusing on adherence to the Consolidated Reporting Guidelines for Prognostic and Diagnostic Machine Learning Models ...
Unexpected outcomes of tislelizumab treatment in thoracic metastasis of malignant phyllodes tumors: a case report and literature review [0.03%]
替雷利珠单抗治疗恶性叶状肿瘤胸腔转移意外疗效的病例报告和文献回顾
Yihao Liu,Zhixuan Duan,Minghui Liu et al.
Yihao Liu et al.
Phyllodes tumo (PT) of the breast are classified into benign, borderline, and malignant types. Malignant phyllodes tumor (MPT) with metastasis, particularly those containing sarcomatous components, have a notably poor prognosis. The most co...