Clinical outcomes of DNA-damaging agents and DNA damage response inhibitors combinations in cancer: a data-driven review [0.03%]
DNA损伤剂和DNA损伤响应抑制剂在癌症治疗中的临床疗效:一种数据驱动的综述
Rick Fontenot,Neha Biyani,Kishor Bhatia et al.
Rick Fontenot et al.
The combination of DNA-damaging agents (DDAs) and DNA damage response inhibitors (DDRis) has been extensively studied to improve therapeutic outcomes. While both groups of agents show promise individually, DDAs are limited by tumor resistan...
Dissection of 4L lymph node for left-sided non-small cell lung cancer: a meta-analysis [0.03%]
左肺非小细胞肺癌患者左侧第4组淋巴结解剖的 Meta 分析
Chenxi Li,Zhuozheng Hu,Jiajun Wu et al.
Chenxi Li et al.
Background: The therapeutic efficacy of left lower paratracheal (4L) lymph node dissection in the management of left-sided non-small cell lung cancer (NSCLC) remains an unresolved clinical question. Therefore, we conducte...
Nanoemulsion of myricetin enhances its anti-tumor activity in nude mice of triple-negative breast cancer xenografts [0.03%]
纳米乳制剂(myricetin)对三阴乳腺癌裸鼠移植瘤的增效抗肿瘤作用研究
Preeti Sharma,Yogesh Rai,Mohammad Ahmed Khan et al.
Preeti Sharma et al.
Purpose: Myricetin, a naturally occurring flavonoid exhibits good anti-cancer properties. However, its practical application is limited due to poor aqueous solubility and low bioavailability. To overcome these challenges,...
Food-derived compounds targeting ferroptosis for cancer therapy: from effects to mechanisms [0.03%]
食物衍生化合物在癌症治疗中铁死亡靶向作用:从效应到机制
Jin-Wei Zhao,Wei-Yi Zhao,Zhongyang Yu
Jin-Wei Zhao
Ferroptosis is distinctive type programmed cell death. Tumor cells, with their higher iron levels, render them more susceptible to ferroptosis Inducing ferroptosis can activate immune cells, regulate immune evasion, and inhibit the biology ...
Low-dose ATG/PTCy for graft-versus-host disease prevention in haploidentical transplantation: a single-center experience [0.03%]
小剂量ATG/PTCY预防单倍型移植后移植物抗宿主病的疗效及安全性:单一中心经验
Jian Hong,Xinglin Liang,Jing Ni et al.
Jian Hong et al.
Background: The combination of anti-thymocyte globulin (ATG) and post-transplant cyclophosphamide (PTCy) has been administered for graft-versus-host disease (GVHD) prophylaxis of haploidentical hematopoietic stem cell tra...
HER2 and hormone receptor conversion after neoadjuvant therapy for breast cancer [0.03%]
乳腺癌新辅助治疗后的HER2和激素受体转阳
Jing Wang,Xin Long,Mingxi Tang et al.
Jing Wang et al.
Background: The expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) in residual lesions may be different compared with primary tumors of the breast after n...
Application of the Monaco-serial biological function for cardiac dose constraints in DIBH-IMRT treatment planning for left-sided breast cancer [0.03%]
蒙特卡洛序贯生物函数在左乳腺癌DIBH-IMRT治疗计划中心脏剂量约束的应用研究
Haili Hu,Zhou Jueyi,Jiang Hao et al.
Haili Hu et al.
Background: The Serial function in the Monaco treatment planning system is essential for cardiac dose optimization in left breast cancer radiotherapy; however its optimal K-value for deep-inspiration breath-hold intensity...
Chimeric antigen receptor (CAR) -T cell therapy treatment Richter's transformation [0.03%]
嵌合抗原受体-T细胞治疗里特尔转化症
Shaomei Feng,Peihao Zheng,Haidi Liu et al.
Shaomei Feng et al.
Background/purpose: Despite advances in chronic lymphocytic leukemia treatment, effective therapies for cases with Richter's transformation (RT) are urgently needed. This study aimed to investigate the use of chimeric ant...
Prediction of HER2 expression in breast cancer patients based on multi-parametric MRI intratumoral and peritumoral radiomics features combined with clinical and imaging indicators [0.03%]
基于多模态MRI肿瘤内和肿瘤周纹理特征结合临床及影像学标志物预测乳腺癌患者HER2表达
Xiaoxiao Li,Junfang Fang,Fuqian Wang et al.
Xiaoxiao Li et al.
Objective: To preoperatively evaluate the HER2 status in breast cancer using multiparametric MRI intratumoral and peritumoral radiomics features combined with clinical and imaging characteristics. ...
Contemporary epidemiological landscape of pediatric non-Hodgkin lymphoma: a global burden of disease analysis [0.03%]
儿童非霍奇金淋巴瘤的当代流行病学格局——全球疾病负担分析
Xiaobo Luo,Pin Xie,Min Zhou et al.
Xiaobo Luo et al.
Introduction: This study evaluated the distribution characteristics, influencing factors, and future trends of non-Hodgkin lymphoma (NHL) burden in children and adolescents globally from 1990 to 2021. ...