Integrative analysis of polyamine metabolism-related genes in gliomas: implications for prognosis and therapy [0.03%]
胶质瘤中多胺代谢相关基因的综合分析：预后和治疗意义
Yujia Zhao,Zhenkai Fu,Sijie Chen et al.
Yujia Zhao et al.
Introduction: Tumor transformation and progression are accompanied by multiple carcinogenic pathways that dysregulate polyamine demand and metabolism. The importance of polyamines has demonstrated that their metabolism is...
Predicting lymphovascular space invasion in early-stage cervical squamous cell carcinoma using heart rate variability [0.03%]
基于心率变异性预测早期宫颈鳞癌淋巴血管间隙浸润
Junlong Fang,Ming Liu,Zhijing Song et al.
Junlong Fang et al.
Background: Accurate preoperative assessment of lymphovascular space invasion (LVSI) in patients with early-stage cervical squamous cell carcinoma (ECSCC) is clinically significant for guiding treatment decisions and pred...
Rashida Ginwala,Laura Bukavina,Mohit Sindhani et al.
Rashida Ginwala et al.
Background: The microbiome is widely known to cause come types of cancer, modify cancer biology, and impact therapeutic efficacy. Despite the urinary microbiome being one of the most clinically significant microbiomes in ...
Performance of the neutrophil-to-lymphocyte ratio as a prognostic tool for survival in solid cancers [0.03%]
中性粒细胞与淋巴细胞比值对实体瘤患者预后的预测价值分析
Irene Carrión-Barberà,Christian Lood
Irene Carrión-Barberà
Neutrophils and lymphocytes are crucial players in cancer progression, with the neutrophil-to-lymphocyte ratio (NLR) emerging as a potential prognostic biomarker. However, its clinical relevance remains uncertain. This study retrospectively...
A multimodal nomogram for benign-malignant discrimination of lung-RADS ≥4A nodules: integration of oxygen enhanced zero echo time MRI, CT radiomics, and clinical factors [0.03%]
一种针对肺-RADS≥4A结节的良恶性鉴别诊断多模态列线图：整合了增强型氧气零回波时间MRI、CT影像组学和临床因素
Tiancai Yan,Ling Liu,Yuxin Li et al.
Tiancai Yan et al.
Background and objective: Lung-RADS ≥4A nodules require urgent intervention. Low-dose CT (LDCT), the primary screening tool, involves cumulative radiation exposure-critical for patients with serial scans. Oxygen-enhanced...
Fertility preservation and assisted reproductive strategies in endometrial cancer patients with lynch syndrome [0.03%]
利什曼病患者的生育力保留和辅助生殖策略
Junhan Liu,Ying Zheng,Jianhong Liu
Junhan Liu
Patients with LS-EC can be treated with progestin-based fertility-sparing treatment under close monitoring, and pregnancy is recommended as soon as possible after complete remission (CR) of the disease, with assisted reproduction, supplemen...
Radiotherapy combined with anlotinib for refractory leiomyosarcoma: a case report and literature review [0.03%]
放射治疗联合阿尼鲁单抗治疗难治性平滑肌肉瘤一例及文献复习
Ziming Li,Xiuchun Yu,Ming Xu
Ziming Li
Refractory leiomyosarcoma (LMS) is characterized by notoriously high recurrence rates and poses significant surgical challenges due to its anatomical complexity and invasive growth patterns. When complete surgical resection proves unattaina...
A multi-algorithm prognostic model combining inflammatory indices and surgical features in distal cholangiocarcinoma [0.03%]
结合炎症指标和手术特征的远端胆管癌多算法预测模型
Yi Yin,Luyuan Bai,Xinyue Mu et al.
Yi Yin et al.
Background: Derived neutrophil-to-lymphocyte ratio (dNLR) is an emerging blood-based inflammatory biomarker previously reported to have prognostic value in various malignancies. This study aimed to investigate the prognos...
Impact of duration of maintenance immunotherapy on the prognosis of locally advanced non-small cell lung cancer treated with chemoradiotherapy [0.03%]
维持免疫治疗时长对同期放化疗局部晚期非小细胞肺癌预后影响分析
HuiQi Fan,Song Guan,Kai Ren et al.
HuiQi Fan et al.
Purpose: Chemoradiotherapy combined with consolidation immunotherapy is the standard of care for unresectable stage III non-small cell lung cancer; however, the optimal number of cycles of consolidation immunotherapy rema...
Significance of FXa and its receptor PAR2 for the growth of colon cancer cells in vitro and in vivo [0.03%]
FXa及其受体PAR2对体外和体内结肠癌细胞生长的意义
Ulrike Meyer,Vincent Rönnpagel,Sophie Grammbauer et al.
Ulrike Meyer et al.
Colon cancer is among the most common cancer types worldwide. Signaling pathways that control cell proliferation and migration play a crucial role in its progression. The G-protein-coupled protease-activated receptors (PARs) are associated ...