Leveraging deep learning for early detection of cervical cancer and dysplasia in China using U-NET++ and RepVGG networks [0.03%]
基于U-NET++和RepVGG网络的中国宫颈癌及宫颈上皮内瘤变早期智能检测研究
Baoqing Li,Lulu Chen,Chudi Sun et al.
Baoqing Li et al.
Background: Cervical cancer is a significant global public health issue, primarily caused by persistent high-risk human papillomavirus (HPV) infections. The disease burden is disproportionately higher in low- and middle-i...
Editorial: The role of adjuvant and neoadjuvant therapy in resectable esophageal cancer [0.03%]
论著：可切除食管癌的辅助与新辅助治疗地位
Xiaokun Li,ZhuangZhuang Cong,Yong Qiang
Xiaokun Li
Lidia Castagneto-Gissey,Dragos Eugen Georgescu,Ferdinando Agresta
Lidia Castagneto-Gissey
Application of immunotherapy in advanced non-small cell lung cancer with hypertension: a multicenter retrospective analysis [0.03%]
免疫治疗在高血压合并晚期非小细胞肺癌中的应用效果分析：多中心回顾性研究
Jingyi Yuan,Kaixin Lei,Quanling Kong et al.
Jingyi Yuan et al.
Importance: Immune checkpoint inhibitors (ICIs) have become the standard treatment for advanced non-small cell lung cancer (NSCLC). However, their prognostic role in NSCLC patients remains controversial. Hypertension (HTN...
Case Report: A case of carcinoma in situ of the bladder misdiagnosed as "chronic prostatitis" for a long time [0.03%]
病例报告：一例误诊为“慢性前列腺炎”的膀胱原位癌患者
Chongbin Li,Guiyun Zhu,Jianzhen Liu et al.
Chongbin Li et al.
Background: Carcinoma in situ of the bladder (CIS) has no specific clinical symptoms and is easily confused with inflammatory lesions of the bladder and urethra. It is usually not considered as the primary diagnosis and r...
Diagnosis and management of a rare bilateral ovarian mixed germ cell tumor: a case report [0.03%]
罕见的双侧卵巢混合性生殖细胞肿瘤的诊断和治疗：病例报告
Xuanling Li,Min You,Xiaoyun Zhang et al.
Xuanling Li et al.
Background: Mixed ovarian malignant germ cell tumors (MOGCTs) are rare neoplasms composed of two or more malignant germ cell components, representing less than 1% of all ovarian germ cell tumors. They primarily affect ado...
A predictive model and mechanistic study of treatment effectiveness in patients newly diagnosed with small cell lung cancer [0.03%]
新诊断的小细胞肺癌患者治疗效果的预测模型和机制研究
Tianyun Wang,Qiuyang Lu,Diexiao Luo et al.
Tianyun Wang et al.
Introduction: Extensive-stage small cell lung cancer (ES-SCLC) is an aggressive malignancy with a poor prognosis. This study aimed to identify and validate clinical and laboratory biomarkers for predicting treatment respo...
Carlos Tomás Noblejas Quiles,José Antonio Macías Cerrolaza,Javier David Benitez Fuentes et al.
Carlos Tomás Noblejas Quiles et al.
Vanishing bile duct syndrome (VBDS) is a rare but potentially fatal cause of intrahepatic cholestasis, usually associated with autoimmune, infectious or drug-induced etiologies. We present the first documented case of VBDS induced by Atezol...
FGFR2 expression relates to subtype-specific tumour microenvironment (TIME) during luminal breast cancer evolution [0.03%]
FGFR2的表达在腔内型乳腺癌的发生发展中与特定亚型的肿瘤微环境（TME）相关
Julia Sołek,Aleksandra Zielińska,Radzisław Kordek et al.
Julia Sołek et al.
Background: Fibroblast growth factor receptor 2 (FGFR2) is an oncogenic driver in luminal breast cancer (BCa), with emerging evidence linking it to tumour immune microenvironment (TIME) modulation. While FGFR2's role in e...
Analysis of brain necrosis and secondary cancers after proton beam therapy for pediatric intracranial tumors: a single-center retrospective study [0.03%]
质子治疗儿科脑部肿瘤后继发性脑坏死和癌症的分析：单中心回顾性研究
Masashi Mizumoto,Hiroko Fukushima,Yoshiko Oshiro et al.
Masashi Mizumoto et al.
Background: Proton beam therapy (PBT) is increasingly used for pediatric intracranial tumors due to lower long-term radiation-associated toxicities. However, data on late adverse effects, particularly brain necrosis and i...