Clinical referral to the NHS following multi-cancer early detection test results from the NHS-Galleri trial [0.03%]
NHS临床转诊：NHS-Galleri试验多癌症早期检测结果分析
Ian Lowenhoff,Saoirse Dolly,Rebecca Dowinton Smith et al.
Ian Lowenhoff et al.
Introduction: The large, randomised, controlled NHS-Galleri trial (NCT05611632) is assessing the clinical utility of a multi-cancer early detection (MCED) test for asymptomatic cancer screening in England. We describe how...
A nomogram with the peripheral blood neutrophil-to-lymphocyte ratio before treatment predicts the survival of patients with nasopharyngeal carcinoma [0.03%]
治疗前外周血中性粒细胞与淋巴细胞比值预测鼻咽癌患者预后简易图的建立及验证
Huai-Wen Zhang,Liu Feng,Hao-Wen Pang et al.
Huai-Wen Zhang et al.
Background: This study was performed to investigate the relationship of the pretreatment neutrophil count and neutrophil-to-lymphocyte ratio (NLR) with the prognosis of nasopharyngeal carcinoma (NPC), as well as to establ...
Integrated analysis identifies P4HA2 as a key regulator of STAT1-mediated colorectal cancer progression and a potential biomarker for precision therapy [0.03%]
整合分析鉴定出P4HA2是STAT1介导的结直肠癌进展的关键调节因子及潜在精准治疗生物标志物
Qianshi Zhang,Yinan Zhang,Zhiwei Sun et al.
Qianshi Zhang et al.
Introduction: P4HA2 is implicated in regulating tumor microenvironment formation and may play roles in inflammation and tumor immunity. However, its mechanistic involvement in colorectal cancer (CRC) remains largely unexp...
Pathologic complete response after Sintilimab combined with FOLFOX therapy in MSI-H type patients with locally advanced GC: a case report [0.03%]
西妥昔单抗联合FOLFOX治疗MSI-H型局部进展期胃癌患者并获得病理完全缓解：1例报告
Xiaoke Wang,Yuanhui Gu,Lin Yi et al.
Xiaoke Wang et al.
As one of the most common gastrointestinal tumors, Gastric Cancer (GC) poses a serious threat to human health due to its high morbidity and mortality. The current treatment strategy is a comprehensive treatment program mainly based on surge...
Clinical value of CA125, AFP, and CEA for combined diagnosis and assessment of gastric cancer prognosis [0.03%]
CA125、AFP和CEA在胃癌联合诊断及预后评估中的临床价值分析
Yanhai Jia,Yajuan Wang,Haiying Li et al.
Yanhai Jia et al.
To analyze the diagnostic and prognostic value of combined detection of CA125, AFP, and CEA for gastric cancer. Ninety-eight gastric cancer patients treated in our hospital from January 2020 to November 2022 were retrospectively selected an...
Effect of post-mastectomy radiation therapy on survival in breast cancer with lymph nodes micrometastases: a meta-analysis and systematic review [0.03%]
乳腺癌淋巴结微转移保乳术后放疗的疗效分析及系统评价
Jianqing Zheng,Bifen Huang,Ying Chen et al.
Jianqing Zheng et al.
Background: Axillary management of patients with early-stage breast cancer (ESBC) has evolved, especially with the implementation of precision radiotherapy techniques that have resulted in a significant reduction in treat...
The value of a combined model based on ultra-radiomics and multi-modal ultrasound in the benign-malignant differentiation of C-TIRADS 4A thyroid nodules: a prospective multicenter study [0.03%]
基于超辐射组学和多模态超声的联合模型在C-TIRADS 4A甲状腺结节良恶性鉴别中的价值：一项前瞻性多中心研究
Shuai Cui,Qifan Liu,Hailong Wang et al.
Shuai Cui et al.
Objective: To establish a combined model based on ultrasound radiomics combined with multimodal ultrasound and evaluate its value in diagnosing benign and malignant nodules classified as Chinese-Thyroid Imaging Report and...
Gut microbes and immunotherapy for non-small cell lung cancer: a systematic review [0.03%]
肠道微生物与非小细胞肺癌免疫治疗：系统性综述
Yali Jin,Zhiqian Jie,Xianming Fan
Yali Jin
Emerging evidence underscores gut microbiota's role in modulating lung cancer immunotherapy outcomes, though specific impacts on immune checkpoint inhibitors (ICIs) and associated adverse events (AEs) require further clarity. This review sy...
Development of a nomogram for predicting recurrence of epithelial ovarian cancer involving traditional Chinese medicine treatment [0.03%]
一个用于预测涉及中医治疗的卵巢癌复发的列线图的发展
Xiaofeng Chen,Xudong Hu,Huanmei Lin et al.
Xiaofeng Chen et al.
Background: The treatment of epithelial ovarian cancer (EOC) is evolving towards personalization and precision. Early prediction of recurrence can provide a basis for individualized monitoring and treatment. Our study aim...
The m6A reader YTHDF3 promotes TNBC progression by regulating CENPI stabilization [0.03%]
YTHDF3通过调节CENPI稳定促进三阴性乳腺癌进展
Yulu Zhang,Shunji Chen,Qiaosheng Wu
Yulu Zhang
Background: RNA N 6-methyladenosine (m6A) readers mediate cancer progression. However, the role of eiptranscriptomic modifications such as m6A in the regulation of TNBC progression is unclear. ...