Case Report and review of the literature: A rare cut - surgical resection of primary CNS EBV- positive T-cell lymphoma [0.03%]
病例报告及文献回顾：一例罕见的中枢神经系统原发性EB病毒阳性T细胞淋巴瘤的手术切除术报告
Lykourgos Anastasopoulos,Eirini Charalampopoulou,Theodoros Argyrakos et al.
Lykourgos Anastasopoulos et al.
Primary central nervous system T-cell lymphoma (PCNS-TCL) is an exceptionally rare entity, representing less than 5% of all PCNSLs. Its diagnosis is frequently delayed due to nonspecific radiologic features and an often absent or poor respo...
Xing-Xing Li,Jia-Li Chen
Xing-Xing Li
Lung cancer (LC) is a significant global health concern, underscoring the need for ongoing research into novel therapeutic modalities. Trophoblast cell surface antigen-2 (TROP2) is overexpressed in tumor tissues and minimally expressed in n...
A rare case report of uterine carcinosarcoma with bilateral ovarian Brenner tumors [0.03%]
子宫癌肉瘤伴双侧卵巢Brenner瘤的罕见病例报告
Xinyao Wan,Fangfang Bi,Bing Xin et al.
Xinyao Wan et al.
Background: Uterine carcinosarcoma is a rare, highly aggressive malignancy characterized by both carcinomatous and sarcomatous components. Brenner tumors of the ovary are uncommon epithelial neoplasms, usually benign but ...
Residual/recurrent lesions after cold-knife conization for high-grade cervical intraepithelial neoplasia: risk factor analysis and clinical management recommendations [0.03%]
冷冻刀宫颈锥切治疗高级别宫颈上皮内瘤变后残余/复发病变的风险因素分析及临床处理建议
Chenchun Wu,Peng Guo,Pengchong Huang et al.
Chenchun Wu et al.
Objective: This study aims to evaluate the risk factors of residual/recurrent lesions of cervical intraepithelial neoplasia 2/3 (CIN2/3) in patients who underwent cold-knife conization (CKC). ...
Case Report: complete response to preoperative ipilimumab and nivolumab combination therapy in advanced papillary renal cell carcinoma with inferior vena cava tumor thrombus and multiple metastases [0.03%]
病例报告：用于治疗腔静脉肿瘤血栓和多发转移的晚期乳头状肾细胞癌的术前伊匹单抗和纳武利尤单抗联合治疗取得完全反应
Chika Nagahisa,Kazuhiko Yoshida,Shuhei Nozaki et al.
Chika Nagahisa et al.
Introduction: Combination therapy comprising ipilimumab and nivolumab is a safe and effective treatment for advanced renal cell carcinoma (RCC). However, its use in papillary RCC (pRCC) with an inferior vena cava (IVC) tu...
Early detection of left fallopian tube carcinosarcoma by transvaginal sonography: a case report and review of diagnostic challenges [0.03%]
电视超声早期诊断左侧输卵管癌肉瘤1例并文献复习
Junjie Chang,Wenjun Zhang,Hua Wang et al.
Junjie Chang et al.
Fallopian tube carcinosarcoma (FTCS) is an extremely rare and aggressive malignancy, its nonspecific clinical presentation and anatomical location make preoperative diagnosis challenging, often lead to delayed treatment and poor outcomes. H...
Identification of a novel PRMD16:: SKI fusion gene in T-prolymphocytic leukemia [0.03%]
T-脯氨酰胺肽酶淋巴细胞白血病中新型PRDM16-SKI融合基因的鉴定
Marta Brunetti,Hilde Kollsete Gjelberg,Håkon Reikvam et al.
Marta Brunetti et al.
The presence of the PRDM16::SKI fusion gene was described, for the first time, in a T prolymphocytic leukemia (T-PLL) patient with a long indolent period and a late development treatment requiring disease. The fusion transcript was detected...
Identifying sinonasal inverted papilloma by machine learning: a systematic review and meta-analysis [0.03%]
机器学习识别鼻窦倒置乳头状瘤的系统评价和荟萃分析
Xianfei Qin,Jinping Shi,Xiangkun Zhao et al.
Xianfei Qin et al.
Background: Sinonasal inverted papilloma (IP) is a benign tumor of the sinonasal mucosa, which may become malignant. Machine learning (ML) has been applied to improve the accuracy in the diagnosis of various diseases, but...
NFIA-dependent upregulation of SMC4 promotes metastasis and metabolic reprogramming in glioma [0.03%]
NFIA通过上调SMC4促进胶质瘤的转移和代谢重编程
Guoyin Li,Yukui Zhao,Yubo He et al.
Guoyin Li et al.
Background: Gliomas, particularly glioblastoma, are aggressive brain tumors with poor prognosis and unmet therapeutic needs. Structural maintenance of chromosomes 4 (SMC4), a core component of the condensin complex, is dy...
hNIS-based imaging to monitor treatment with the novel oncolytic virus CF33-hNIS-antiPDL1 in humans with advanced triple negative breast cancer [0.03%]
基于hNIS的成像技术监测新型溶瘤病毒CF33-hNIS-antiPDL1治疗三阴性乳腺癌患者的疗效研究
Jamie Rand,Dave Yamauchi,Shyambabu Chaurasiya et al.
Jamie Rand et al.
Background: Triple-negative breast cancer (TNBC) is clinically aggressive. CF33-hNIS-antiPDL1, an oncolytic orthopoxvirus, shows robust anti-cancer activity in TNBC xenografts in mice. CF33-hNIS-antiPDL1-infected tumor ce...