Case Report: IL-6 suppression: a potential strategy for mitigating severe immune-related adverse events in nivolumab and ipilimumab therapy for malignant pleural mesothelioma [0.03%]
病例报告：抑IL-6可能是减轻尼伏单抗和伊匹单抗治疗恶性胸膜间皮瘤所引起严重免疫相关不良反应的潜在策略
Asako Yanagisawa,Takumi Fukaya,Kento Noda et al.
Asako Yanagisawa et al.
Background: Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer with a poor prognosis, often presenting challenges in treatment. The CheckMate-743 trial demonstrated significant improvements in overall su...
Analysis of treatment options and survival outcomes for patients with localized prostate cancer: a focus on androgen deprivation therapy [0.03%]
局限性前列腺癌治疗方式及预后分析：重视雄激素剥夺疗法的影响
Zhiqiang Li,Shiwei Sun,Chenghao Tan et al.
Zhiqiang Li et al.
Background: Management of localized prostate cancer (PCa) remains challenging in resource-limited settings where access to surgery and radiotherapy is restricted. This study assessed the survival outcomes of patients rece...
Efficacy and safety of male fertility-sparing radical cystectomy with orthotopic neobladder versus radical cystectomy and nerve-sparing cystectomy: a meta-analysis [0.03%]
保留男性生育力的原位新膀胱根治性膀胱切除术与根治性膀胱切除及神经保留手术的有效性和安全性的meta分析研究
Yu Huang,Hongjin Shi,Qun Wang et al.
Yu Huang et al.
Background: Radical cystectomy (RC) serves as the gold standard treatment for organ-localized bladder cancer; however, postoperative complications diminish the quality of life of patients. Whether male fertility-sparing r...
Decoding the immune microenvironment in osteosarcoma: new insights into checkpoints, vaccines, and CAR-T cells [0.03%]
解码骨肉瘤免疫微环境：对检查点、疫苗和CAR-T细胞的新认识
Haitian Wang,Tongtong Zhu,Kunpeng Yang et al.
Haitian Wang et al.
Osteosarcoma (OS), the most prevalent primary malignant bone tumor, disproportionately affects adolescents and is marked by rapid progression and a high rate of pulmonary metastasis. Despite advances in multimodal treatment, outcomes remain...
Predicting EGFR gene mutation in lung adenocarcinoma using spectral CT combined with AI parameters: a diagnostic accuracy study [0.03%]
基于光谱CT结合AI参数预测肺腺癌EGFR基因突变的诊断准确性研究
Lilan She,Min Xie,Guolin Xu et al.
Lilan She et al.
Purpose: Epidermal growth factor receptor(EGFR) mutation is one of the most critical biomarkers in non-small cell lung cancer (NSCLC), holding significant clinical implications for guiding targeted therapy selection and p...
The therapeutic efficacy of 225Ac-DOTATATE in neuroendocrine tumors: a preliminary meta-analysis [0.03%]
锕-225-DOTAATATE治疗神经内分泌肿瘤的疗效：一项初步meta分析研究
Jiao Ma,Yang Ji,Zhihan Yao et al.
Jiao Ma et al.
Objective: This meta-analysis aims to evaluate the therapeutic efficacy and toxicity of 225Ac-DOTATATE in patients with metastatic neuroendocrine tumors (NETs). ...
Global, regional, and national burden of ovarian cancer attributable to high body mass index, 1990-2021: insights from the global burden of disease study 2021 [0.03%]
2021年全球、区域和国家与高体重指数相关的卵巢癌疾病负担（1990-2021）：来自2021年全球疾病负担研究的启示
Yinghua Wang,Yuexin Yu
Yinghua Wang
Objective: Building on established evidence linking excess body fatness to increased risk of ovarian cancer, this research aims to assess the global and regional disease burden of ovarian cancer attributable to high body ...
Identification and prognostic prediction of high-risk multiple myeloma by exosomal microRNA [0.03%]
通过外泌体微小核糖核酸鉴定高危多发性骨髓瘤及预后预测
Ying Tian,Wenjiao Tang,Chunlan Zhang et al.
Ying Tian et al.
Introduction: Circulating exosomal miRNAs have emerged as important tools for liquid biopsy in cancer diagnosis and prognosis prediction. This project establishes a plasma exosomal miRNA-based system for diagnosing multip...
Preoperative plasma fibrinogen combined with the platelet-to-lymphocyte ratio (F-PLR) serves as a prognostic indicator in patients with non-small cell lung cancer [0.03%]
术前血浆纤维蛋白原联合血小板淋巴比值(F-PLR)可作为非小细胞肺癌患者预后指标
Hongzhen Zhao,Xiaopeng Zhang,Dahu Ren et al.
Hongzhen Zhao et al.
Background: The aim of this study was to explore the prognostic significance of the combined plasma fibrinogen level and platelet-to-lymphocyte ratio (F-PLR) score in patients who had undergone radical surgery for non-sma...
To predict the spread through air spaces in lung adenocarcinoma using radiomic features from different regions of part-solid nodules: a multicenter study [0.03%]
基于不同部分实性结节区域的影像组学特征预测肺癌腺癌沿气腔播散的多中心研究
Shiyu Cui,Hongzheng Song,Fanxia Lin et al.
Shiyu Cui et al.
Background: This study aims to explore the value of radiomic features from different regions of part-solid nodules (PSNs) for predicting spread through air spaces (STAS) in lung adenocarcinoma. ...