Immunotherapy combined with chemotherapy: a promising therapeutic approach in the management of colonic squamous cell carcinoma-a case report [0.03%]
免疫治疗联合化疗在结肠鳞状细胞癌综合治疗中的应用——一例报告
Bingbing Ren,Haitao Yang,Yingying Mao
Bingbing Ren
Colorectal squamous cell carcinoma (CSCC) is an exceedingly rare malignancy, accounting for approximately 0.41% of all colorectal cancers. This case report describes a 52-year-old male with a history of chronic bronchitis, varicose vein of ...
Nontargeted metabolomics uncovering metabolite signatures in glioblastoma: a preliminary study on candidate biomarker discovery for IDH subtyping and survival prediction [0.03%]
非靶向代谢组学揭示胶质母细胞瘤中的代测标志物：异柠檬酸脱氢酶亚型鉴别和生存预测的候选生物标志物研究的一项初步研究
Peng Xu,Xiling Chen,Qun Li et al.
Peng Xu et al.
Background: Currently, there are no established tumor-derived metabolic biomarkers in clinical practice that can simultaneously differentiate among nontumorous brain tissues, isocitrate dehydrogenase (IDH) wild-type gliob...
CD38 prognostic role in chronic lymphocytic leukemia patients treated with standard chemotherapy or targeted agents: a monocentric real-life experience [0.03%]
CD38在慢性淋巴细胞白血病患者标准化疗或靶向治疗中的预后作用：单中心真实世界经验
Laura Mettivier,Danilo De Novellis,Anna Maria Della Corte et al.
Laura Mettivier et al.
Introduction: Therapeutic strategies for patients affected by Chronic Lymphocytic Leukemia (CLL) have undergone significant changes over the last decade, shifting from chemoimmunotherapy to targeted therapy. ...
Combined stereotactic radiation therapy and immunotherapy for metastatic uveal melanoma [0.03%]
立体定向放射治疗与免疫治疗联合治疗脉络膜黑色素瘤转移病灶
Valeria V Nazarova,Kristina V Orlova,Zakhra R Magomedova et al.
Valeria V Nazarova et al.
Aim: Uveal melanoma (UM) is a rare primary intraocular malignant tumor with an extremely poor prognosis. Our study evaluated the feasibility to improve metastatic UM treatment outcomes with a combined approach of immunoth...
Liming Xiao,Ziyi Zhao,Li Zhou et al.
Liming Xiao et al.
Primary thyroid lymphoma is a rare hematologic malignancy of the thyroid gland, accounting for approximately 5% of all malignant thyroid tumors. The most common pathological type is B-cell-derived non-Hodgkin's lymphoma, mainly diffuse larg...
Critical review of OCT in clinical practice for the assessment of oral lesions [0.03%]
OCT在口腔病变评估临床实践中的批判性评价
Fariba Esperouz,Domenico Ciavarella,Mauro Lorusso et al.
Fariba Esperouz et al.
Background: Optical Coherence Tomography (OCT) is an advanced imaging technique that is widely used in ophthalmology and is increasingly being applied in other fields of medicine. In oral oncology, OCT offers high-resolut...
HIF-1α modulates pancreatic cancer ECM proteins via the TGF-β1/Smad signaling pathway introduction [0.03%]
HIF-1α通过TGF-β1/Smad信号通路调节胰腺癌ECM蛋白的表达
Houle Guo,Zhanxue Zhao,Linxun Liu
Houle Guo
Introduction: Pancreatic cancer is characterized by its aggressive nature and poor prognosis, ranking among the most lethal malignancies. The tumor microenvironment, particularly the extracellular matrix (ECM), plays a cr...
Targeted therapy acts to sensitize stereotactic body radiotherapy for pulmonary oligometastases from colorectal cancer [0.03%]
靶向治疗可增敏肺转移病灶立体定向放疗作用研究(colorectal cancer肺转移病灶)
Xiye Sun,Pei Shu,Yali Shen et al.
Xiye Sun et al.
Background: Stereotactic body radiation therapy (SBRT) is used to manage lung metastases arising from colorectal cancer (CRC), but its effectiveness is constrained by the radioresistance of CRCs. Here, we explored whether...
Impact of secondary hematologic malignancies on prognosis of Hodgkin's lymphoma survivors [0.03%]
继发性血液系统恶性肿瘤对霍奇金淋巴瘤幸存者预后的影响
Fangheng Lin,Debin Liu,Tao Huang et al.
Fangheng Lin et al.
Background: The purpose of this study is to report the differences in the prognosis of Hodgkin's lymphoma (HL) survivors with or without secondary hematologic malignancies (SHM). ...
Implementing treatment according to the guidelines is of paramount importance in locally advanced cervical cancer: a real-world study [0.03%]
根据指南治疗在局部晚期宫颈癌中至关重要——一项真实世界的研究
Ester Jääskeläinen,Henna Kärkkäinen,Jan-Erik Palmgren et al.
Ester Jääskeläinen et al.
Background: External beam radiotherapy with concomitant chemotherapy and image-guided brachytherapy is the standard treatment for locally advanced cervical cancer. This retrospective study compared real-world outcomes wit...