NGS coverage accurately predicts MET and HER2 (ERBB2) gene amplifications in a real-world non-small cell lung cancer cohort [0.03%]
基于真实世界数据的非小细胞肺癌队列中NGS覆盖率准确预测MET和HER2（ERBB2）基因扩增
Adam Kowalewski,Janna Siemanowski-Hrach,Thomas Stehle et al.
Adam Kowalewski et al.
Background: Fluorescence in situ hybridization (FISH) is the current standard for detecting gene amplifications, yet its low throughput and practical constraints call for alternative methods. This study evaluates next-gen...
Zhenzhou Gao,Haokai Qin,Bao Li et al.
Zhenzhou Gao et al.
Adrenal Ganglioneuroma (AGN) is a rare benign tumor that is mostly nonfunctioning and usually presents without significant clinical symptoms. AGN can undergo calcification, but rarely presents with hemorrhage, necrosis, or cystic changes. T...
Case Report: Unveiling the hidden: a rare case of endometrial tuberculosis presenting as peritoneal carcinomatosis [0.03%]
个例报道：揭开隐藏的真相：一例以腹膜癌综合征形式表现的子宫内膜结核罕见病例
Mariem Garci,Mehdi Makni,Ghada Abdelmoula et al.
Mariem Garci et al.
Background: Endometrial tuberculosis (TB) is a rare form of extrapulmonary TB, particularly uncommon in postmenopausal women. Its atypical presentation, characterized by nonspecific symptoms, often leads to misdiagnosis, ...
Imaging features of pancreatic extragastrointestinal stromal tumors: a case report and literature review [0.03%]
胰腺胃肠道间质瘤以外的胃肠间质瘤的影像学特征一例及文献复习
Jian-Xia Xu,Meng-Yin Gu,Yi-Hua Wang et al.
Jian-Xia Xu et al.
Pancreatic extra-gastrointestinal stromal tumors (pEGISTs) are exceedingly rare, accounting for less than 5% of all extra-gastrointestinal stromal tumors (EGISTs). We report a case involving a 62-year-old woman who presented with a hypervas...
Nestin in multiple myeloma: emerging insights into a potential therapeutic target [0.03%]
巢氏蛋白与多发性骨髓瘤：潜在治疗靶点的新视野
Yingmiao Wu,Ji Luo,Yue Zhou et al.
Yingmiao Wu et al.
Multiple myeloma (MM) is the second most common hematological malignancy and remains incurable, with high rates of relapses and refractory. One of the root causes is the presence of multiple myeloma stem cells (MMSCs). The deficiency of MMS...
Dosimetric analysis of orthogonal collimator configuration in volumetric modulated arc therapy planning: a comparative study [0.03%]
体积调强旋转治疗计划中正交准直器配置的剂量分析：比较研究
Xin Huang,Chenlei Guo,Shuangtong Liu et al.
Xin Huang et al.
Background: In volumetric modulated arc therapy (VMAT), collimator angle selection impacts dose distribution and plan quality. Conventional VMAT plans use dual arcs with collimators set at 0˚. This study explores the dos...
Metastatic squamous cell carcinoma of mediastinal lymph nodes from the ileum: a case report and literature review [0.03%]
肠起源的纵隔淋巴结转移性鳞状细胞癌一例及文献复习
Yanan Zhang,Yumeng Yue,Zongxing Zhao et al.
Yanan Zhang et al.
Mediastinal lymph node metastasis from squamous cell carcinoma (SCC) is one of the most common sites for regional metastasis in thoracic malignancies. However, SCC originating from the ileum is relatively rare. We herein report a case of me...
Huiling Wang,Huijuan Dai,Liheng Zhou et al.
Huiling Wang et al.
Backgrounds: Triple-negative breast cancer (TNBC) represents the most aggressive breast cancer subtype. The limited treatment options underscore the urgent need to explore novel molecular targets to combat TNBC progressio...
Efficacy and safety of TACE-HAIC combined with tyrosine kinase inhibitors and immune checkpoint inhibitors for the patients with BCLC-defined stage B-C HCC [0.03%]
TACE-HAIC联合酪氨酸激酶抑制剂和免疫检查点抑制剂治疗巴塞罗那分期B期至C期肝细胞癌患者的疗效及安全性
Bowen Liu,Linan Yin,Yuxin Chen et al.
Bowen Liu et al.
Background: To evaluate the therapeutic efficacy and safety profile of combining transarterial chemoembolization (TACE) with hepatic arterial infusion chemotherapy (HAIC) combined with tyrosine kinase inhibitors (TKIs) an...
Yongming Lin,Xinru Xie,Jiayi Wang et al.
Yongming Lin et al.
With the increasing incidence of breast malignant tumours in the population, some rare cases of breast cancer have been reported. We would like to share with you a case of placental metastasis of a malignant tumour of the breast: the patien...