SFRT combined with immunotherapy for a growing hepatocellular carcinoma after the failure of anti-angiogenesis and anti-PD1 treatment: a case report [0.03%]
抗血管生成和抗PD1治疗失败后的肝癌生长病例报告:采用SFRT联合免疫疗法治疗
Jiamiao Hu,Yue Jin,Mengjia Wang et al.
Jiamiao Hu et al.
Background: Hepatocellular carcinoma (HCC) is one of the prevalent tumors worldwide, posing a global healthcare threat. The existing treatment options for large HCC have poor therapeutic effects and are prone to drug resi...
Decoding the microbial-local immune dialogue in liver cancer: from ecological drivers to precision therapeutics [0.03%]
解码肝癌中的微生物-局部免疫对话:从生态驱动因素到精准治疗
Yichi Xu,Bo Wen,Nan Gao et al.
Yichi Xu et al.
The global incidence and mortality rates of liver cancer remain persistently high, attributable to its multifaceted etiology. Recent research has increasingly focused on the interaction between gut microbiota and the liver's immune system. ...
Editorial: Novel molecular targets and therapies for pediatric extracranial solid tumors [0.03%]
编者按:儿童头颅外实体肿瘤的新型分子靶点和治疗手段
Paola Angelini,Aditi Vedi,Kavitha Srivatsa
Paola Angelini
Innovative patient-specific delivered-dose prediction for volumetric modulated arc therapy using lightweight Swin-Transformer [0.03%]
基于轻量级Swin-Transformer的体积调强弧形治疗患者特异性给药剂量预测创新方法
Yongqiang Zhou,Changfei Gong,Junming Jian et al.
Yongqiang Zhou et al.
Background: Volumetric modulated arc therapy (VMAT) necessitates rigorous pre-treatment patient-specific quality assurance (PSQA) to ensure dosimetric accuracy, yet conventional manual verification methods encounter time ...
An overview of the role of radionuclides in targeted cancer treatment: application of biomarkers for patient selection and developments to improve treatment efficacy [0.03%]
放射性核素靶向癌症治疗的生物标志物应用及疗效提高策略研究进展
Tim A D Smith
Tim A D Smith
Radiopharmaceuticals for targeted radionuclide therapy (TRT) of tumours consist of a radionuclide conjugated to a component that can target the cancer. Several TRT radiopharmaceuticals have been licensed for the treatment of lymphoma, neuro...
An interpretable clinical-radiomics-deep learning model based on magnetic resonance imaging for predicting postoperative Gleason grading in prostate cancer: a dual-center study [0.03%]
基于磁共振成像的临床-影像组学-深度学习模型预测前列腺癌术后格利森分级:一项双中心研究
Fuyu Guo,Shiwei Sun,Xiaoqian Deng et al.
Fuyu Guo et al.
Objective: To develop and test an interpretable machine learning model that combines clinical data, radiomics, and deep learning features using different regions of interest (ROI) from magnetic resonance imaging (MRI) to ...
Multimodal prognostic models for bladder urothelial carcinoma: uroplakin III combined with serum and demographic data [0.03%]
膀胱尿路上皮癌的多模态预后模型:尿上皮分化抗原3联合血液及人口统计学数据
Runlin Feng,Jian Hou,Yanping Tao et al.
Runlin Feng et al.
Background: Bladder urothelial carcinoma (BUC) remains a highly recurrent and heterogeneous malignancy. Accurate postoperative risk stratification is crucial to guide adjuvant therapy decisions. We hypothesized that integ...
Evaluation of recent lightweight deep learning architectures for lung cancer CT classification [0.03%]
近期轻量级深度学习架构在肺癌CT分类中评价研究
MennaAllah Mahmoud,Yanhua Wen,Xiaohuan Pan et al.
MennaAllah Mahmoud et al.
Introduction: While numerous large and complex deep learning architectures continue to be developed for medical imaging, clinical adoption remains limited to a small number of established models. Recent lightweight archit...
Metabolome profiling by untargeted metabolomics and biomarker panel selection using machine-learning for patients in different stages of peripheral neuropathy induced by oxaliplatin [0.03%]
无目标代谢组学的代谢轮廓分析及其联合机器学习筛选标志物面板鉴别不同阶段奥沙利铂外周神经毒性患者
Yu-Jiao Hua,Ying Zhang,Rui-Rong Wu et al.
Yu-Jiao Hua et al.
Background: Oxaliplatin-induced peripheral neuropathy (OIPN) poses a significant challenge for patients with colorectal tumor, often resulting in treatment interruption or discontinuation and subsequent treatment failure....
Curative response to combined targeted-immunotherapy for post-hepatectomy lymph node metastasis in sarcomatoid hepatocellular carcinoma: case report and literature review [0.03%]
索拉非尼联合免疫治疗治疗肝细胞癌肉瘤变异型术后淋巴结转移的疗效观察及文献复习:1例报告
Pan Liu,Song Zhang,Xiao-Ming Xin et al.
Pan Liu et al.
Sarcomatoid hepatocellular carcinoma (SHC) is an aggressive malignancy with poor therapeutic outcomes. Current evidence supports radical surgical resection as the primary treatment modality, yet it is associated with prohibitively high post...