Ping Yuan,Weinan Lu,Xia Yong et al.
Ping Yuan et al.
Objective: To evaluate and summarize evidence on intervention of the meaning of life of cancer patients, and provide evidence-based basis for clinical practice. ...
Impact of lymph node dissection on the prognosis of intrahepatic cholangiocarcinoma: a systematic review and meta-analysis [0.03%]
系统评价和Meta分析：肝门淋巴结清扫对肝内胆管癌预后的影响
Jun Yu,Fan Zhou,Xing-Guo Tan et al.
Jun Yu et al.
Background: Intrahepatic cholangiocarcinoma (iCCA) is a malignant tumor second only to hepatocellular carcinoma in terms of incidence among primary liver cancers. Surgical resection is currently the preferred treatment fo...
Postoperative adjuvant hepatic arterial infusion chemotherapy with gemcitabine-cisplatin sequential capecitabine combined with PDL1 inhibitors in resected high-risk intrahepatic cholangiocarcinom: study protocol for a prospective, multicenter, single-arm, phase 2 trial (HgcCP trial) [0.03%]
高风险肝内胆管癌切除术后的吉西他滨-顺铂序贯卡培他滨联合PD-L1抑制剂术后辅助肝动脉灌注化疗：一项前瞻性、多中心单臂Ⅱ期临床研究（HgcCP试验）
Ying Yang,Qing-Yun Xie,Tao Lv et al.
Ying Yang et al.
Background: Although capecitabine is recommended for postoperative adjuvant treatment of biliary tract cancers (BTC), no studies have specifically focused on the postoperative adjuvant treatment of intrahepatic cholangioc...
Molecular subtypes, prognostic factors, and treatment optimization in pediatric medulloblastoma: a real-world study from China [0.03%]
中国儿童髓母细胞瘤分子亚型、预后因素及治疗优化的现实世界研究
Jingjing Liu,Yanling Sun,Huming Li et al.
Jingjing Liu et al.
Background: Medulloblastoma (MB) is the most common malignant pediatric brain tumor, yet systematic studies on molecular characteristics and treatment efficacy in Chinese pediatric MB remain scarce. This study evaluates r...
RNLS promotes ovarian cancer growth and inhibits ferroptosis via mediating STAT3 [0.03%]
RNLS通过介导STAT3促进卵巢癌生长并抑制铁死亡
Liang Lin,Zuolian Xie,Peilin Zhong et al.
Liang Lin et al.
Introduction: Ovarian cancer (OC) is a lethal malignancy for which there are limited therapeutic options. The role of renalase (RNLS) in cancer progression and ferroptosis regulation remains unclear. This study investigat...
Case Report: A familial hematological pedigree reveals VHL germline mutation as a principal predisposition factor with additional mutations modulating phenotypic heterogeneity [0.03%]
个例报告：一家族血液病系谱表明VHL胚系突变是主要的发病因素，另有突变影响表型异质性
HuiLing Chen,Wanli Hu,Chengcheng Ma et al.
HuiLing Chen et al.
Background: VHL germline mutations are classically associated with von Hippel-Lindau syndrome, but their role in hematological malignancies remains underexplored. ...
Fluorescence lifetime imaging microscopy approach reveals quantitative signatures for hepatocellular carcinoma diagnosis [0.03%]
荧光寿命成像显微技术揭示肝细胞癌定量诊断信息
Lingyun Li,Aoshan Wang,Xiongqing Liu et al.
Lingyun Li et al.
Hepatocellular carcinoma (HCC) remains a critical global health challenge, and current histopathological diagnosis relies heavily on hematoxylin and eosin (H&E) staining-a widely adopted clinical tool for assessing tissue morphology. Howeve...
Global, regional, and national burden of Pediatric and adolescent thyroid cancer from 1990 to 2021: a statistical analysis of prevalence, incidence, and DALYs [0.03%]
1990年至2021年全球、区域和国家儿童及青少年甲状腺癌疾病负担：患病率、发病率和DALYS的统计分析
Rui Zhang,Zhenxin Mei,Shan Feng et al.
Rui Zhang et al.
Background: Thyroid cancer is the most common malignant tumor of the endocrine system. Among children and adolescents, cancer ranks as the fourth leading cause of cancer-related deaths. Pediatric and adolescent thyroid ca...
Case Report: Is the isolated bone change in advanced colorectal cancer necessarily malignant metastasis? [0.03%]
病例报告：晚期结直肠癌孤立性骨改变一定是恶性的转移病变吗？
Huimin Xue,Xin Sun,Xiaomei Yang et al.
Huimin Xue et al.
Background: Radiation osteitis (RO) is a bone-related complication following radiotherapy (RT), often characterized by atypical imaging features. It is challenging to distinguish RO from early bone metastasis (BM), potent...
YBX1: an RNA/DNA-binding protein that affects disease progression [0.03%]
YBX1:一种影响疾病发展的RNA / DNA结合蛋白
Xifeng Zheng,Feng Zeng,Yan Lei et al.
Xifeng Zheng et al.
YBX1 is a member of the Y-box transcription factor family and is a multifunctional RNA/DNA-binding protein characterized by a highly conserved cold shock domain (CSD). YBX1 is localized in both the cytoplasm and nucleus, where it participat...