Lower dose and weekly schedules of selinexor in multiple myeloma - updated evidence on safety and efficacy [0.03%]
在多发性骨髓瘤中使用低剂量和每周一次的Selincro方案-安全性和有效性的最新证据更新
Muhamed Baljevic,Gary Schiller,Tomer M Mark et al.
Muhamed Baljevic et al.
Background: Selinexor, a first-in-class, oral exportin-1 inhibitor, showed activity in penta-refractory multiple myeloma (MM) in early trial exploration; however, the side-effect profile of twice-weekly dosing led to hesi...
Intratumoral microbial abundance and load influence the immune microenvironment of oral squamous cell carcinoma [0.03%]
瘤内微生物丰度和负荷影响口腔鳞状细胞癌免疫微环境
Jiajun Fang,Mengna Wu,Hongyu Shen et al.
Jiajun Fang et al.
Objective: This study aimed to explore the characteristics intratumoral microbiome in oral squamous cell carcinoma, and elucidate the interplay between intratumoral microbial profiles (relative abundance/absolute load) an...
A systematic review and meta-analysis of the effects of green tea extracts and polyphenols in female hormone-dependent cancers for benefit-risk evaluation [0.03%]
系统评价和荟萃分析——通过利弊评估评价绿茶提取物和多酚对激素依赖性肿瘤（以女性为主）的影响
Jin-Jing He,Yan-Fang Zhang,Ze-Huang He et al.
Jin-Jing He et al.
Female hormone-dependent cancers rely on estrogen for growth and include breast, uterine and ovarian cancers. Although preclinical studies indicate that green tea extracts and polyphenols derived from green tea exhibit anti-tumor effects wi...
The combination treatment of oncolytic adenovirus H101 with transcatheter arterial embolization sequential thermal ablation for hepatocellular carcinoma: a retrospective study [0.03%]
溶瘤腺病毒H101联合肝癌介入及射频消融序贯治疗的回顾性研究
Changyou Jing,Tong Zhu,Yonghong Zhang et al.
Changyou Jing et al.
Background & aims: Recombinant human adenovirus type 5 (H101) was demonstrated to enhance the efficacy of transcatheter arterial embolization (TAE) for hepatocellular carcinoma (HCC). This study aims to analyze the effica...
Recurrence patterns and prognosis of esophageal cancer patients based on the Rbr resection status [0.03%]
基于Rbr切除状态的食管癌患者复发模式及预后分析
Peng Zhang,Guoqing Zhang,Kaishang Zhang et al.
Peng Zhang et al.
Introduction: Despite achieving complete resection (R0) and pathological complete response (pCR) in esophageal squamous cell carcinoma (ESCC) patients, recurrence is still observed, resulting in poorer overall survival (O...
Treating and triggering hyperinflammation: tackling hemophagocytic lymphohistiocytosis and HLH-like syndromes in the pediatric cell therapy and critical care setting [0.03%]
儿科细胞治疗和重症监护室中噬血细胞性淋巴组织细胞增多症及其类似综合征的治疗与诱因：应对措施
Holly Wobma,Lauren A Henderson,Christine N Duncan et al.
Holly Wobma et al.
Hemophagocytic lymphohistiocytosis (HLH) describes a severe, hyperinflammatory syndrome that can originate from diverse etiologies, often requiring critical care level management. Primary HLH, initially described in the 1940s, derives from ...
Predicting resectability after neoadjuvant chemotherapy for patients with borderline resectable pancreatic cancer: a single center, retrospective trial [0.03%]
新辅助化疗后边缘可切除胰腺导管腺癌患者能否手术的预测因素：单中心回顾性研究
Florian Schepp,Sebastian Hempel,Felix von Bechtolsheim et al.
Florian Schepp et al.
Background/objectives: Pancreatic ductal adeno carcinoma (PDAC) in its borderline resectable (BR) stage often limits the possibility of complete resection, currently the only potential path to a cure. Neoadjuvant chemothe...
Prevalence and prognostic value of sarcopenia in patients with bladder cancer undergoing radical cystectomy: a systematic review and meta-analysis [0.03%]
系统评价与meta分析：肌肉减少症在行根治性膀胱切除术的膀胱癌患者中的流行病学特征及预后价值
Lei Zhang,Fanmin Li,Lemei Liu et al.
Lei Zhang et al.
Background: The relationship between sarcopenia and clinical outcomes in patients with bladder cancer (BC) has been inconsistently reported in the literature. Some studies have identified sarcopenia as a potential prognos...
Prognostic and clinicopathological value of prognostic nutritional index in patients with multiple myeloma: a meta-analysis [0.03%]
预后营养指数在多发性骨髓瘤患者中的预后及临床病理价值：一项系统评价和Meta分析
Yanchen Nie,Zongxin Zhang,Xiaohuan Tang
Yanchen Nie
Background: Prognostic nutritional index (PNI) has been extensively investigated for its effect on forecasting multiple myeloma (MM) survival; however, the conclusions are conflicting. This meta-analysis identified an acc...
Correction of breast deformities after breast-conserving surgery in Chinese women with breast cancer: a narrative review [0.03%]
乳腺癌保乳术后中国女性乳房畸形的整形矫正：综述性文章
Zejun Wu,Long Zhong,Jiaxu Gu et al.
Zejun Wu et al.
Breast-conserving therapy (BCT) is a key treatment option for early-stage breast cancer, balancing oncologic control with cosmetic outcomes. However, postoperative breast deformities occur in approximately 25% to 30% of cases, significantly...