Mechanism of active component β-sitosterol from Myristica fragrans inducing apoptosis in bladder cancer cells via regulating the BCL-2/BAX/caspase-3 pathway [0.03%]
肉豆蔻含活性成分β-谷甾醇通过调节BCL-2/BAX/CASPASE-3通路诱导膀胱癌细胞凋亡的机制研究
Yongkang Zhu,Zhao Tang,Zhaoyue Lu et al.
Yongkang Zhu et al.
Background: Nutmeg (Myristica fragrans) has been traditionally used in herbal medicine, but its potential anti-cancer effects remain largely unexplored. This study aimed to investigate the molecular mechanisms of nutmeg a...
Global, regional, and national burden and trends of pancreatic cancer, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021 [0.03%]
1990年至2021年全球、区域和国家胰腺癌疾病负担及变化趋势：2021年全球疾病负担研究系统分析
Chunlong Liu,Pengpeng Liu,Xue Liu et al.
Chunlong Liu et al.
Background: To evaluate temporal trends, associated risk factors, and cross-national inequalities in the distribution of pancreatic cancer from 1990 to 2021. ...
Daily online adaptation enhances target coverage in prostate cancer radiotherapy: a retrospective analysis [0.03%]
每日在线自适应提高前列腺癌放射治疗的靶区覆盖率：回顾性分析
Hanna Malygina,Bryan Salazar Zuniga,Hendrik Auerbach et al.
Hanna Malygina et al.
Introduction: Online adaptive radiotherapy aims to improve treatment quality by accounting for inter-fractional variation in anatomy. This study presents a quantitative comparison between adapted and non-adapted scheduled...
Definitive radiotherapy for local and metastatic lesions in prostate cancer patients with oligometastases [0.03%]
寡转移前列腺癌患者局部及转移病灶的根治性放射治疗
Bichun Xu,Xianzhi Zhao,Yiyin Liang et al.
Bichun Xu et al.
Background: Few studies explore the role of definitive radiotherapy for prostate and all metastases in the treatment of low-burden oligometastatic prostate cancer (omPCa). This study aimed to investigate the potential sur...
Tall cell carcinoma with reversed polarity of breast cancer: a rare case report and review of the literature [0.03%]
高细胞癌乳腺癌极性反转型的一种罕见病例报告及文献回顾
Wenqi Duan,Longmei Zhang,Jinqi Gao et al.
Wenqi Duan et al.
Tall cell carcinoma with reversed polarity (TCCRP) is a primary invasive breast cancer that is clinicopathologically characterized by reversed polarity of the nucleus of the tumor cells near the cell edge. This pathologic feature is so rare...
Complete response of advanced HER2-amplified lung adenocarcinoma to cadonilimab combined with disitamab vedotin: a case report [0.03%]
卡度尼利联合迪伐单抗治疗晚期HER2扩增肺腺癌的完全应答：一例报告
Yue Li,Keru Ma,Hao Wang et al.
Yue Li et al.
Background: Human epidermal growth factor receptor 2 (HER2) gene amplification in lung adenocarcinoma is associated with aggressive tumor behavior and poor prognosis. Currently, there is no standard targeted therapy for H...
Evaluation of the diagnostic value of magnetic resonance imaging combined with ultrasound and mammography for breast cancer using array spatial sensitivity encoding technique [0.03%]
采用空间敏感度编码技术评估乳腺磁共振成像联合超声和钼靶对乳腺癌诊断价值的效果研究
Yingyi Xia,Zhiyu Ling,Hao Chen
Yingyi Xia
Objective: This study aimed to evaluate the diagnostic efficacy of magnetic resonance imaging (MRI) combined with ultrasound and mammography for breast cancer (BC) using array spatial sensitivity encoding technique (ASSET...
Circulating free DNA as a predictive biomarker for response to nivolumab and platinum-based chemotherapy in metastatic esophageal adenocarcinoma: a prospective pilot study [0.03%]
循环游离DNA作为预测生物标志物评估nivolumab联合以铂类为基础的化疗治疗转移性食管腺癌患者的前瞻性研究
Qing Sheng Du,Bo Fan
Qing Sheng Du
Background: Reliable biomarkers are urgently needed to predict response to immune checkpoint inhibitors in metastatic esophageal adenocarcinoma (mEAC). This study evaluated early circulating free DNA (cfDNA) dynamics as a...
Yingfeng Zhang,Qin Qin
Yingfeng Zhang
Artificial intelligence (AI) is revolutionizing oncology, with deep learning (DL) emerging as a pivotal technology for addressing gynecologic malignancies (GMs). DL-based models are now widely applied to assist in clinical diagnosis and pro...
Long-term nutrition therapy leads to survival benefit in head and neck cancer patients receiving targeted or immunotherapy. A retrospective cohort study with real-world data [0.03%]
长期营养治疗可使接受靶向或免疫治疗的头颈部肿瘤患者获益。一项基于真实世界数据的回顾性队列研究
Barbara Belak,Erzsebet Palfi,Andrea Molnar et al.
Barbara Belak et al.
Background: Nutritional status is one of the most important prognostic factors of survival in patients with recurrent or metastatic head and neck cancer (R/M HNC), and it can be positively influenced by medical nutrition ...