Transcriptomic analysis reveals TME-mediated macrophage IFIT1 upregulation and CX3CR1 suppression drive osteosarcoma progression [0.03%]
转录组分析揭示了肿瘤微环境介导的巨噬细胞IFIT1上调和CX3CR1抑制驱动骨肉瘤进展
Keyi Wang,Huanyang He,Jiamin Liang et al.
Keyi Wang et al.
Introduction: Osteosarcoma (OS) is one of the most common bone tumors with an unsatisfactory prognosis for patients. Due to the stagnation in conventional treatments, researchers are exploring therapeutic targets from the...
Microsurgical treatment of breast cancer-related lymphedema under contrast-enhanced ultrasound guidance: a case report and literature review [0.03%]
微波消融联合手术切除治疗肺多发转移癌一例及文献复习
Qiuchan Zhao,Xing Huang,Weizhang Chen et al.
Qiuchan Zhao et al.
Lymphedema remains a chronic and challenging condition with limited curative options. Recent advances have expanded treatment strategies from comprehensive conservative management to microsurgical interventions, particularly lymphaticovenou...
Serial TIL infusions and PD-1 blockade drive long-term clonal persistence in prostate cancer [0.03%]
前列腺癌序贯输注肿瘤浸润淋巴细胞和PD-1阻断可长期保持克隆扩增
Lucas C M Arruda,Julia Karbach,Dragan Kiselicki et al.
Lucas C M Arruda et al.
Adoptive cell therapy using tumor-infiltrating lymphocytes (TIL) can achieve durable responses in patients with metastatic cancers, but the long-term clonal dynamics after multiple administration and synergy with checkpoint blockade remain ...
Severe and/or prolonged COVID-19 in hematologic diseases: clinical implications before and during the omicron era [0.03%]
血液系统疾病的严重和/或长期COVID-19：奥米克戎时代之前的临床意义及时代的临床意义
Akinao Okamoto,Masahiro Yoshida,Senji Kasahara et al.
Akinao Okamoto et al.
Background: Although the Omicron variant has been reported to reduce COVID-19 severity in the general population, its impact on patients with hematologic malignancies remains uncertain, and epidemiological investigation i...
The association between coronary heart disease and the risk of developing colorectal polyps: insights from the UK Biobank [0.03%]
冠心病与结直肠息肉发病风险关联的研究：英国生物银行的洞见
Chi Geng,Ruochong Pang,Yuqing Xia et al.
Chi Geng et al.
Background: While numerous risk factors for colorectal polyps (CRPs) have been identified, the impact of coronary heart disease (CHD) on the etiology of CRPs remains ambiguous. ...
Artificial intelligence-based evaluation of prognostic benefits from immunotherapy plus targeted therapy with or without radiotherapy or TACE in advanced hepatocellular carcinoma [0.03%]
基于人工智能评估免疫治疗联合靶向治疗±放射或TACE在晚期肝细胞癌中预后收益的影响
Yuehong Deng,Shiqin Song,Huarong Zhao et al.
Yuehong Deng et al.
Background: Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, and the prognosis of advanced disease is still poor. Immunotherapy plus targeted therapy has reshaped systemic trea...
Mortality from sepsis among middle-aged and elderly patients with pancreatic cancer: CDC WONDER 1999 To 2023 [0.03%]
1999年至2023年美国中老年胰腺癌患者脓毒症死亡的CDC数据探究
Aiyu Guan,Yan Chen,Yuhong Li et al.
Aiyu Guan et al.
Introduction: Sepsis-related mortality in middle-aged and older pancreatic cancer patients constitutes a significant public health issue. This study seeks to analyze trends in the age-adjusted mortality rate (AAMR) for se...
Knowledge map of recurrence in tenosynovial giant cell tumor: a bibliometric analysis [0.03%]
肌腱滑膜巨细胞瘤复发的知识图谱:一次文献计量分析
Pan Gao,Shuo-Cheng Ji,Wei Liang et al.
Pan Gao et al.
Purpose: Tenosynovial Giant Cell Tumor (TGCT) is a rare benign neoplasm originating from the synovium and tendon sheath, and is characterized by a relatively high rate of recurrence following treatment. The present study ...
Prognostic value of the GRANT score and development of a nomogram in papillary renal cell carcinoma: a SEER-based study with external validation in a Chinese cohort [0.03%]
基于SEER数据库的乳头状肾细胞癌预后列线图的建立及在中国队列中外部验证研究
Tongpeng Liu,Wei Chen,Yu Yao et al.
Tongpeng Liu et al.
Background: Papillary renal cell carcinoma (pRCC) exhibits significant heterogeneity, and robust prognostic tools specifically validated for this subtype are lacking. The GRANT score, incorporating grade, age, nodes, and ...
Case Report: Extra skeletal Ewing's sarcoma of mediastinum: clinical experience and literature review [0.03%]
胸膜外尤文氏肉瘤的病例报告：临床经验与文献回顾
Xianwen Hu,Wei Zhao,Ronghua Yu et al.
Xianwen Hu et al.
Extraskeletal Ewing sarcoma (EES) is a malignant tumor that arises in soft tissues outside the skeleton. It commonly involves the paravertebral regions, the lower extremities, and the chest wall, with mediastinal involvement being less freq...