Consensus on managing delayed methotrexate elimination in high-dose therapy: insights from the Middle East [0.03%]
高剂量治疗中管理甲氨蝶呤延迟排泄的处理共识：来自中东的见解
Mubarak Al Manasour,Ahmad Absi,Ahmad Alhuraiji et al.
Mubarak Al Manasour et al.
Introduction: High-dose methotrexate (HDMTX) therapy is a cornerstone in treating pediatric and adult cancers, namely, acute lymphoblastic leukemia, non-Hodgkin lymphoma, and osteosarcoma, due to its capability to penetra...
Implementation research on common cancers (lung, breast, and colorectal) in Asia - a systematic review [0.03%]
亚洲常见癌症（肺癌、乳腺癌和结直肠癌）实施研究的系统评价
Ansuman Panigrahi,Swati Sambita Mohanty,Purnashashi Behera et al.
Ansuman Panigrahi et al.
Introduction: Implementation research is crucial for implementing evidence-based interventions in real-world settings. This study aims to assess and collate existing evidence on implementation research related to common c...
CricRNA in head and neck squamous cell carcinoma: biological functions and clinical prospects [0.03%]
头颈部鳞状细胞癌中的环形RNA：生物学功能和临床前景
Anqi Li,Zhen Dong,Chunming Zhang
Anqi Li
Head and neck squamous cell carcinoma (HNSCC) is a prevalent malignant tumor globally, shows an unfavorable prognosis and has a five - year survival rate lower than 50%. Circular RNA (circRNA) is defined as a type of non-coding RNA molecule...
Sintilimab plus a bevacizumab biosimilar (IBI305) in advanced HCC with Child-Pugh A/B liver function: a real-world multicenter retrospective study [0.03%]
sintilimab联合贝伐珠单抗类似物(IBI305)治疗Child-PughA/B肝功能的晚期HCC患者：一项真实世界多中心回顾性研究
Yuanxu Zhang,Youhan Miao,Wei Sun et al.
Yuanxu Zhang et al.
Background: Sintilimab plus a Bevacizumab biosimilar (IBI305) is an approved first-line regimen for unresectable hepatocellular carcinoma (uHCC) in China. However, data on its safety and efficacy in patients with impaired...
Combined imaging and serum biomarkers in CEUS-guided microwave ablation for hepatocellular carcinoma: A meta-analysis [0.03%]
弹性超声造影引导下的微波消融治疗肝癌的影像及血清生物标志物的Meta分析
Xiaoli Zou,Danyi Zhao,Yu Shang et al.
Xiaoli Zou et al.
Objective: This study aimed to evaluate the efficacy of a treatment strategy that actively integrates imaging features and serum biomarkers into contrast-enhanced ultrasound (CEUS)-guided microwave ablation (MWA) for hepa...
The role of lactylation in breast cancer development: mechanisms, clinical translation and new strategies for treatment [0.03%]
乳酰化在乳腺癌发生发展中的作用：机制、临床转化及新的治疗策略
Yanzhen Lu,Xiaoting Yang,Lulu Tan et al.
Yanzhen Lu et al.
Worldwide, breast cancer (BC) is a common and deadly illness that poses a serious risk to women's health. Its development is intimately associated with tumor microenvironment (TME) alteration and metabolic problems. Lactic acid, a principal...
Prostate cancer evolution after COVID-19-related prostatitis in a TMPRSS2-altered patient: a case report and review of the molecular interface between SARS-CoV-2 and prostate oncogenesis [0.03%]
TMPRSS2改变型前列腺癌患者的COVID-19相关前列腺炎后前列腺癌演变：病例报告及SARS-CoV-2与前列腺肿瘤发生分子界面的文献回顾
Fabricio Borges Carrerette,Magda Conceição Barbosa Gomes,Romulo Varella de Oliveira et al.
Fabricio Borges Carrerette et al.
Background: SARS-CoV-2 exploits TMPRSS2, an androgen-regulated protease highly expressed in prostate tissue, to enter host cells. While inflammation is a recognized promoter of oncogenesis, the possibility that viral pros...
Case Report: A new noninvasive device-based treatment of a mesencephalic H3 K27M glioma [0.03%]
案例报告：一种新的非侵入性装置用于治疗中脑H3 K27M胶质瘤
Santosh A Helekar,Omkar B Ijare,Martyn A Sharpe et al.
Santosh A Helekar et al.
Brainstem gliomas have a poor prognosis and ineffective therapeutic options. We have developed a noninvasive device called an Oncomagnetic device that produces selective oncolysis of gliomas in vitro and marked reduction of contrast-enhance...
Experience sharing of endoscopy-assisted total mastectomy with and without immediate breast reconstruction [0.03%]
内镜辅助乳房切除术（联合即刻乳房重建）的临床应用体会
Yidan Lin,Minxue Zhuang,Hongbin Qiu et al.
Yidan Lin et al.
Objective: To evaluate safety, efficacy, and aesthetics of endoscopy-assisted total mastectomy endoscope(EATM) with immediate breast reconstruction (IBR). ...
Early C-reactive protein reduction predicts survival in real-world extensive-stage small cell lung cancer treated with first-line adebrelimab-based immunotherapy [0.03%]
基线C-反应蛋白早期降低可预测广泛期小细胞肺癌真实世界阿得贝利单抗为基础的一线免疫治疗生存获益
Jian Wang,Xueli Zhang,Qijia Gao et al.
Jian Wang et al.
Background: Extensive-stage small cell lung cancer (ES-SCLC) remains an aggressive malignancy with limited biomarkers for predicting outcomes in real-world settings. While baseline systemic inflammation correlates with pr...