Advances in neoantigen-based immunotherapy for head and neck squamous cell carcinoma: a comprehensive review [0.03%]
基于新抗原的免疫疗法在头颈部鳞癌中进展及其展望:全面回顾
Manzhu Jiang,Jiefu Li,Jianhua Wei et al.
Manzhu Jiang et al.
Head and Neck Squamous Cell Carcinoma (HNSCC), ranking among the six most prevalent malignancies worldwide, is characterized by significant heterogeneity. Conventional monotherapeutic approaches, including surgical intervention, radiotherap...
Construction of a predictive model for cervical lymph node metastasis in papillary thyroid carcinoma [0.03%]
构建乳头状甲状腺癌颈淋巴结转移的预测模型
YanHong Hao,Yuan Su,Yanan Li et al.
YanHong Hao et al.
Background: In oncology, the relationships among cervical central lymph node metastasis (CLNM), biochemical tests, and ultrasound characteristics in patients with papillary thyroid cancer (PTC) remain controversial. This ...
Early prediction of colorectal adenoma risk: leveraging large-language model for clinical electronic medical record data [0.03%]
基于临床电子病历数据的大语料库模型在早期预测结直肠腺瘤风险中的应用研究
Xiaoyu Yang,Jinjian Xu,Hong Ji et al.
Xiaoyu Yang et al.
Objective: To develop a non-invasive, radiation-free model for early colorectal adenoma prediction using clinical electronic medical record (EMR) data, addressing limitations in current diagnostic approaches for large-sca...
Study on the mechanism by which Xuanfu Hua Tang increases sensitivity of hepatocellular carcinoma cells to sorafenib by antagonizing the Notch1 pathway through HIF-2α [0.03%]
旋复花汤通过HIF-2α拮抗Notch1信号通路增敏肝癌细胞索拉非尼敏感性的机制研究
Wenzhao Luo,Xian Li,Yiwan Shang et al.
Wenzhao Luo et al.
Background: It is crucial to explore ways to increase the sensitivity of hepatocellular carcinoma cells to sorafenib. Methods: The HepG...
Impact of Hashimoto's thyroiditis on ultrasound diagnosis of papillary thyroid carcinoma: a retrospective study [0.03%]
桥本甲状腺炎对乳头状癌超声诊断影响的回顾性研究
Chao Teng,Kunkun Pang,Lulu Zhang et al.
Chao Teng et al.
Objective: To investigate the clinical features and ultrasonic manifestations of papillary thyroid carcinoma (PTC) with Hashimoto's thyroiditis (HT) and without HT. The characteristics were analyzed to improve the accurac...
Exploring two tumor treatment strategies: effectiveness of ribosome inactivating proteins and mesenchymal stem cells/MSC derived extracellular vesicles in cancer treatment [0.03%]
探讨两种肿瘤治疗策略:核糖体失活蛋白和间充质干细胞/间充质干细胞源性外泌体的抗癌效果
Maryamosadat Mavaei,Simin Farokhi,Mohammad Hasan Yousefi et al.
Maryamosadat Mavaei et al.
Cancer is a complex and heterogeneous disease that often requires multifaceted treatment strategies to achieve optimal therapeutic outcomes. Given the limitations of single-agent therapies, particularly in the face of intricate biological s...
Divergent gene expression of PTGS1 and PTGS2 along the disease course of chronic myeloid leukaemia [0.03%]
慢性粒细胞白血病疾病进程中的PTGS1和PTGS2基因表达差异性研究
Denise K Wosniaki,Bianca N Kusma,Anelis M Marin et al.
Denise K Wosniaki et al.
Introduction: Chronic myeloid leukaemia (CML) is a chronic myeloproliferative disorder caused by the reciprocal translocation of chromosomes 9 and 22. This genetic abnormality leads to the uncontrolled proliferation of my...
Factors affecting survival prognosis of patients with rectal cancer after neoadjuvant chemoradiotherapy [0.03%]
新辅助化疗联合放疗后直肠癌患者预后影响因素分析
Baokun Li,Jiachao Han,Feifei Wang et al.
Baokun Li et al.
Objective: To identify potential factors influencing the survival prognosis of locally advanced rectal cancer patients receiving neoadjuvant chemoradiotherapy. ...
Exosome, an important transmitter in the drug resistance of non-small cell lung cancer [0.03%]
外泌体在非小细胞肺癌耐药中的重要作用
Hongzhi Ji,Li Zhang,Lingyun Ye
Hongzhi Ji
Recent studies have promoted new insights into the biology of non-small cell lung cancer (NSCLC) and made considerable progress in the field of treatment, including targeted therapy for driver gene mutations. Immunotherapy (IO) is another b...
Circulating tumor DNA laboratory processes and clinical applications in nasopharyngeal carcinoma [0.03%]
鼻咽癌循环肿瘤DNA实验室处理程序及临床应用
Ziman Wu,Haiyan Yang,Xinying Li et al.
Ziman Wu et al.
Circulating tumor DNA (ctDNA), a subset of cell-free DNA (cfDNA), originates from primary tumors and metastatic lesions in cancer patients, often carrying genomic variations identical to those of the primary tumor. ctDNA analysis via liquid...