RET fusion driven (RETfus+) non-small cell lung cancer: a comprehensive genomic profiling study with histologic correlation [0.03%]
RET融合驱动的非小细胞肺癌:全面基因组分析并结合组织学相关性研究
Prashanth Ashok Kumar,Michael Connolly,Alina Basnet et al.
Prashanth Ashok Kumar et al.
Background: Fusion of the RET gene resulting in clinically significant Genomic Alteration (GA) occur in 1-2% of NSCLC in the United States and has emerged as a major target for RET inhibitors which are first line treatmen...
Sirui Zhang,Wenting Peng,Lin Cheng et al.
Sirui Zhang et al.
We describe a 68-year-old man who had prostate cancer (PCa) diagnosed with breast metastasis, presenting as a breast mass. Seven years ago, the patient had PCa with bone metastasis and had been systematically receiving endocrine therapy for...
Meningioma growth beneath the outer membrane of a traumatic chronic subdural hematoma after burr-hole drainage: a case report and literature review [0.03%]
钻孔引流慢性硬膜下血肿外层之下发生脑膜瘤一例及文献复习
Tao Xiong,Wei-Xian Liu,Zhu-Xiao Tang et al.
Tao Xiong et al.
Introduction: Growth of meningiomas secondary to postoperative chronic subdural hematoma is extremely rare. Here, we present the first report of a patient who developed a meningioma within the outer membrane of the chroni...
A trispecific antibody targeting EGFR/cMET/VEGF-A demonstrates multiple mechanisms of action to inhibit wild-type and mutant NSCLC animal models [0.03%]
一种靶向EGFR/cMET/VEGF-A的三特异性抗体在野生型和突变型非小细胞肺癌动物模型中展示出多种抑瘤机制
Ying Jin,Ping Sun,Peng Chen et al.
Ying Jin et al.
Introduction: Non-small cell lung cancer (NSCLC) patients who do not respond to standard of care treatment can have activating mutations in the epidermal growth factor receptor (EGFR) and mesenchymal epithelial transition...
Radio(chemo)therapy with curative intent for anal cancer - effectiveness and toxicity in elderly vs. younger patients [0.03%]
放疗(化疗)治愈性治疗肛癌的效果及毒性:老年患者与年轻患者的比较
Mahalia Zoe Anczykowski,Polina Rösel,David Alexander Ziegler et al.
Mahalia Zoe Anczykowski et al.
Background: Primary radio(chemo)therapy is a therapeutic standard strategy for advanced anal squamous cell carcinoma (ASCC). For elderly patients evidence concerning long-term oncological outcome is scarce. ...
Hepatic epithelioid hemangioendothelioma, a rare liver tumor: a case report and review of the literature [0.03%]
肝上皮样血管内皮细胞瘤:一例报告及文献复习
Chao Deng,Yulong An,Jinli Liu et al.
Chao Deng et al.
Introduction: Hepatic epithelioid hemangioendothelioma (HEHE) is classified as a rare, low-grade malignant neoplasm of vascular origin. This study presents a case report of a young female patient recently diagnosed with H...
Noninvasive prediction of Ki-67 expression level in IDH-wildtype glioblastoma using MRI histogram analysis: comparison and combination of MRI morphological features [0.03%]
基于MRI直方图分析的非侵入性预测IDH野生型胶质母细胞瘤Ki-67表达水平:MRI形态学特征的比较与结合
Qiang Liang,Qiang Li,Xianwang Liu et al.
Qiang Liang et al.
Purpose: To assess and compare the effectiveness of magnetic resonance imaging (MRI) morphological features and MRI histogram analysis in noninvasively predicting Ki-67 expression levels in patients with IDH-wildtype glio...
Prognostic value of the systemic immune-inflammation index in non-small cell lung cancer patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis [0.03%]
免疫检查点抑制剂治疗非小细胞肺癌患者系统性免疫-炎症指数的预后价值:系统评价和meta分析
Guorong Chen,Bahu Bao,Yucai Ye et al.
Guorong Chen et al.
Background: Although the systemic immune-inflammation index (SII) has emerged as a potential prognostic marker in various cancers, its specific role in non-small cell lung cancer (NSCLC) patients undergoing immunotherapy ...
Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case report [0.03%]
A型胸腺瘤伴腺癌的前纵隔碰撞瘤一例报告
Zhongqin Kang,Rong Xu,Weiya Wang et al.
Zhongqin Kang et al.
Collision tumors are defined as the coexistence of two or more histologically distinct tumor types at the same anatomical site. Mediastinal collision tumors constitute an exceptionally rare subtype of these lesions. Clinically and radiologi...
Geographic diversity of human liver cancers mirrors global social inequalities [0.03%]
地理差异下的全球人类肝癌状况映射了社会不平等问题
Luis Cano,Fabien Foucher,Orlando Musso
Luis Cano
Liver cancers show high interindividual and intratumor heterogeneity. Among them, hepatocellular carcinoma (HCCs) represents approximately 90% of liver cancers, followed by intrahepatic cholangiocarcinoma (iCCA; ~10 to 15%), childhood hepat...