The impact of heart irradiation dose on cardiac injury and survival in lung cancer patients after radiotherapy [0.03%]
心脏照射剂量对放射治疗后肺癌患者心脏损伤和生存影响的研究
Bingchen Li
Bingchen Li
Thoracic radiotherapy is a primary treatment modality for lung cancer, with approximately two-thirds of patients receiving it. The association between heart dose and post-radiotherapy survival and cardiac injury represents a critical area o...
Personalized prediction of pathological complete response in breast cancer neoadjuvant therapy: a nomogram combining quantitative MRI biomarkers and molecular subtypes [0.03%]
结合定量磁共振生物标志物和分子亚型的乳腺癌新辅助治疗病理完全缓解个性化预测列线图模型
Zhendong Shi,Xiaoxing Bian,Hanyan Zhu et al.
Zhendong Shi et al.
Purpose: In this study, we aimed to determine the diagnostic performance of MRI in assessing neoadjuvant therapy (NAT) response, investigate determinants of its accuracy, and develop a nomogram for predicting pathological...
Case Report: Dupilumab therapy for immune checkpoint inhibitor-induced bullous pemphigoid enables dual immunotherapy initiation in progressive malignant melanoma [0.03%]
个例报告：Dupilumab治疗免疫检查点抑制剂诱导的大疱性类天疱疮使进展期恶性黑色素瘤能够开始双重免疫治疗
Janine Grüninger,Saskia Lehr,Frank Meiss et al.
Janine Grüninger et al.
Immune checkpoint inhibitors (ICIs) targeting PD-1, PD-L1 and CTLA-4 have transformed the treatment of malignant melanoma, significantly improving patient survival rates. However, these therapies often result in immune-related adverse event...
Efficacy and safety of antiangiogenic agents combined with HIFU in the treatment of advanced liver cancer [0.03%]
抗血管生成药物联合高强度聚焦超声治疗晚期肝癌的疗效及安全性分析
Rong Wu,Qiuling Shi,Dongbiao Liao et al.
Rong Wu et al.
Background: Although antiangiogenic agents and HIFU (High-intensity focused ultrasound) are extensively used in the systematic treatment of advanced primary and secondary liver cancer, respectively, the efficacy and safet...
Scientometric analysis of glioblastoma and blood-brain barrier research (1995-2024): evolving trends and therapeutic challenges [0.03%]
1995-2024年胶质母细胞瘤和血脑屏障研究的科学计量分析：演变趋势与治疗挑战
Xuan-Hao Pan,Nan Wang,Yi-Chun He et al.
Xuan-Hao Pan et al.
Background: Glioblastoma (GBM) is one of the most aggressive neurogenic tumors. Despite advances in treatment, the presence of the blood-brain barrier (BBB) continues to pose significant challenges to effective therapeuti...
Endometrial carcinosarcoma in a young female with absence of established risk factors: a case report [0.03%]
年轻女性子宫内膜癌肉瘤一例及其缺乏高危因素分析
Na Wei,Shifeng Bai,Donghui Kong et al.
Na Wei et al.
Endometrial carcinosarcoma is a rare, aggressive uterine malignancy, usually affecting postmenopausal women with recognised risk factors such as prolonged unopposed oestrogen exposure, tamoxifen use, pelvic irradiation, or high BMI. We repo...
Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy [0.03%]
安格特罗通过抑制PI3K/Akt/mTOR信号通路和激活自噬抑制软骨肉瘤细胞迁移和侵袭
Chun-Fei Wu,Li-Xin Ouyang,Wan-Hao Zhang et al.
Chun-Fei Wu et al.
Objective: Chondrosarcoma, a malignant bone tumor, exhibits a high incidence rate. This study employed network pharmacology and cell-based experiments to explore the molecular mechanisms by which andrographolide (Andro) s...
Association of the triglyceride-glucose index with immunotherapy efficacy and long-term prognosis in advanced Non-small cell lung cancer [0.03%]
甘油三酯-葡萄糖指数与晚期非小细胞肺癌免疫治疗疗效及长期预后的关联性分析
Lijie Ma,Wanling Zhu,Yulang Wang et al.
Lijie Ma et al.
Background: Non-small cell lung cancer (NSCLC), the most common subtype of primary lung cancer, represents a major component of the global cancer burden. Despite the availability of several immunotherapeutic and immune-co...
A global analysis of nasopharynx cancer burden attributable to occupational formaldehyde exposure [0.03%]
职业甲醛暴露所致鼻咽癌疾病负担的全球分析
Jian Li,Yongjing Lai,Anzhou Tang et al.
Jian Li et al.
Background: Occupational formaldehyde is a significant risk factor for nasopharynx cancer. This study aimed to analyze the burden of nasopharynx cancer attributable to occupational formaldehyde using data from the Global ...
A endometrial malignant tumor with yolk sac tumor component: a case report and literature review [0.03%]
含有卵黄囊肿瘤成分的子宫内膜恶性肿瘤一例报告及文献复习
Zicheng Cui,Yuping Shan,Huijun Chu et al.
Zicheng Cui et al.
Background: Primary endometrial yolk sac tumor (YST), as an extragonadal germ cell tumor, is an exceedingly rare malignancy characterized by high aggressiveness and poor prognosis. Currently, there is no standardized and ...