Metabolic reprogramming and therapeutic targeting in non-small cell lung cancer: emerging insights beyond the Warburg effect [0.03%]
肺癌代谢重组及靶向治疗的新认识——超出瓦博格效应之外的新视野
Hong Cai,Feng Zhang,Fang Xu et al.
Hong Cai et al.
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality worldwide. Recent advancements have illuminated the intricate metabolic reprogramming that underpins NSCLC progression and resistance to therapy. Beyond ...
Application and recent advances in conventional biomarkers for the prognosis of papillary thyroid carcinoma [0.03%]
传统标志物在乳头状甲状腺癌预后中的应用及最新研究进展
Muzi Li,Qiong Li,Cancan Zou et al.
Muzi Li et al.
Cancer remains one of the most common and deadliest diseases worldwide. Among endocrine neoplasms, the incidence of thyroid malignancies has been rising in recent years. Papillary thyroid carcinoma (PTC), the most frequently observed histol...
PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-analysis [0.03%]
抗PD-1/PD-L1联合贝伐珠单抗和化疗与抗PD-1/PD-L1联合化疗治疗晚期非小细胞肺癌：基于三期RCT的Meta分析
Chao Song,Yuan Qiu,Huan Fan et al.
Chao Song et al.
Background: Combining PD-1/PD-L1 inhibitors with chemotherapy (PIC) is a standard first-line treatment for advanced non-small cell lung cancer (NSCLC). The addition of bevacizumab to this regimen (PD-1/PD-L1 inhibitors+be...
Analysis of prognostic factors and risk prediction in brain metastases: a SEER population-based study [0.03%]
美国人群数据库中脑转移患者预后因素及风险预测分析
Qiang Ji,Zixuan Yang,Xun Kang et al.
Qiang Ji et al.
Background: This study investigates survival disparities and prognostic factors in patients with brain metastases originating from various primary cancers to facilitate risk stratification and enhance precision in diagnos...
Virtual phantom methodology for assessment of MRI distortion correction in high-precision stereotactic radiosurgery treatment planning [0.03%]
虚拟体模在高精度放射外科治疗计划MRI畸变校正评估中的方法学研究
Tristan Belloeil-Marrane,Adrian Gutierrez,Marlies Boussaer et al.
Tristan Belloeil-Marrane et al.
Introduction: The accuracy of stereotactic treatment planning is primarily limited by the least accurate process in the whole chain of events, and is particularly important in cranial radiosurgery. Ameliorating this proce...
Novel compound heterozygous PIEZO1 variants in dehydrated hereditary stomatocytosis initially suspected as myelodysplastic syndromes: a case report [0.03%]
脱水遗传性口形红细胞增多症疑似骨髓增生异常综合征病例报告的一项新复合杂合PIEZO1变异研究
Yongcheng Sun,Tao Wang,Shuyan Wang et al.
Yongcheng Sun et al.
Introduction: Dehydrated hereditary stomatocytosis (DHS) is a rare autosomal dominant congenital non-immune hemolytic anemia caused by pathogenic variants in the PIEZO1 gene. Its clinical presentation often overlaps with ...
Curcumin inhibits colorectal cancer progression by targeting PTBP1 and CDK2-mediated pathways [0.03%]
姜黄素通过靶向PTBP1和CDK2介导的途径抑制结直肠癌的发展
Hao Zheng,Shenglong Li,Ye Wang et al.
Hao Zheng et al.
Background: Colorectal cancer (CRC) remains a significant cause of cancer-related mortality worldwide. Curcumin, a natural polyphenol, has shown promise in targeting key cancer pathways, but its precise molecular mechanis...
Advances of oncolytic vaccinia viruses armed with interleukin in tumor therapy [0.03%]
武装了白细胞介素的溶瘤痘病毒在肿瘤治疗中的进展
Mingyong Zha,Fei Huang,Songlin Li et al.
Mingyong Zha et al.
Oncolytic vaccinia viruses armed with interleukins represent a promising frontier in tumor therapy. Oncolytic vaccinia viruses express IL-2, IL-10, IL-12, IL-15, IL-21, IL-23, IL-24, and IL-36γ remodel the tumor microenvironment,enhance im...
Impact of neoadjuvant immunotherapy combined with chemotherapy or chemoradiotherapy on postoperative safety in locally advanced esophageal squamous cell carcinoma: a propensity score-matched retrospective cohort study [0.03%]
新辅助免疫治疗联合化疗或放化疗对局部晚期食管鳞癌术后安全性的影響：倾向性评分匹配回顾性队列研究
Yixin Li,Gang Xiao,Bo Yang et al.
Yixin Li et al.
Introduction: The combination of immunotherapy with neoadjuvant chemotherapy (nICT) or chemoradiotherapy (nICRT) represents a novel treatment approach for patients with locally advanced esophageal squamous cell carcinoma ...
Preventing and managing pharyngocutaneous fistula after total laryngectomy - A narrative review [0.03%]
全喉切除术后咽皮瘘的预防和管理——综述性评论一篇文章
Cesare Piazza,Claudia Montenegro,Vincent Vander Poorten
Cesare Piazza
Pharyngocutaneous fistula (PCF) remains one of the most frequent and serious complications following total laryngectomy (TL). PCF can lead to severe health issues such as infections and thromboembolic events prolonging hospitalization, as w...