Surufatinib related nephrotic syndrome in a pancreatic neuroendocrine tumor: a case report and review of literature [0.03%]
磺瑞替尼相关的肾病综合征在1例胰腺神经内分泌肿瘤患者中的报道及文献回顾
Chengqian Shi,Jinglian Lin,Xiadan Xiang et al.
Chengqian Shi et al.
Pancreatic neuroendocrine tumors (pNETs) are rare, heterogenous neoplasms originating from pancreatic neuroendocrine cells, which regulate hormone secretion and metabolic homeostasis. Surgery is the primary method of control and potential c...
Antiproliferative and pro-apoptotic effects of Pseudevernia furfuracea (L.) Zopf extract and its active component physodic acid via oxidative stress and DNA damage in breast cancer cells [0.03%]
Pseudevernia furfuracea（L.）Zopf提取物及其活性成分physodic酸通过乳腺癌细胞中的氧化应激和DNA损伤产生抗增殖和促凋亡作用
Dominika Sebova,Simona Zilakova,Viktoria Medvecova et al.
Dominika Sebova et al.
Background: Mammary gland malignancies are the most diagnosed oncological diseases in women. The currently available treatment faces several problems, including resistance to cytostatics and the relatively high recurrence...
A dual readout embryonic zebrafish xenograft model of rhabdomyosarcoma to assess clinically relevant multi-receptor tyrosine kinase inhibitors [0.03%]
一种双读数胚胎斑马鱼横纹肌肉瘤异种移植模型，用于评估临床相关的多受体酪氨酸激酶抑制剂
Joseph W Wragg,Emma L Gray,Rui Monteiro et al.
Joseph W Wragg et al.
Background: Rhabdomyosarcoma (RMS) is a highly aggressive soft tissue sarcoma, affecting children and adolescents, with poor prognosis in some patient groups. Better therapeutic regimens and preclinical models to test the...
Case Report: Multiple primary bilateral lung benign notochord cell tumors combined with sacral tumors [0.03%]
案例报道：多原发双肺良性脊索细胞瘤合并骶骨肿瘤
Minjia Tao,Peijun Gao,Jiajie Liu et al.
Minjia Tao et al.
Benign notochord cell tumor (BNCT) in the bilateral lungs is exceedingly rare. This report details a case of a male patient diagnosed with primary bilateral lung BNCTs and concurrent sacral tumors. As part of a routine health check-up, a ch...
Yinwu Kong,Han Bai,Feifei Deng et al.
Yinwu Kong et al.
Current clinical cancer treatments primarily rely on surgery, chemotherapy, radiotherapy, and immunotherapy; however, each approach has inherent limitations. In recent years, nanomaterials have gained significant attention in oncology due t...
Role of TGFβ-activated cancer-associated fibroblasts in the resistance to checkpoint blockade immunotherapy [0.03%]
转化生长因子活化的癌相关成纤维细胞在免疫检查点抑制剂治疗抵抗中的作用研究
Weibin Hou
Weibin Hou
Immune checkpoint blockers (ICBs) have revolutionized cancer treatment by enabling durable responses. However, most patients showed resistance and limited efficacy. Elucidating mechanisms of resistance is imperative to extend the clinical u...
Case Report: Remarkable and sustained remission of an anaplastic thyroid carcinoma patient to the combined treatment of multimodal radiotherapy, anlotinib and toripalimab [0.03%]
个例报告：多模态放射治疗、安罗替尼和特瑞普利单抗联合治疗间变性甲状腺癌的显著且长期的疗效
Yurou Xing,Xuehu Wu,Zhihui Li et al.
Yurou Xing et al.
Anaplastic thyroid carcinoma (ATC) is an infrequent malignant tumor that has a high death rate and a poor prognosis. The therapeutic methods for ATC include traditional surgery, chemoradiotherapy and targeted therapy. However, the effect of...
Clinical characteristics of diffuse large B-cell lymphoma complicated with multiple primary malignant neoplasms [0.03%]
弥漫型大B细胞淋巴瘤合并多原发恶性肿瘤的临床特征分析
Mingxi Tian,Xuejiao Gu,Bin Lv et al.
Mingxi Tian et al.
Objective: To investigate the clinical features and prognosis of diffuse large B-cell lymphoma (DLBCL) combined with multiple primary malignant neoplasms (MPMNs). ...
Multifactorial risk stratification for central lymph node metastasis in papillary thyroid carcinoma: a predictive model integrating clinical and tumor characteristics [0.03%]
多因素分析建立分化型甲状腺癌中央区淋巴结转移的风险分层及预测模型
Huaiyu Yang,Liyuan Wei,Jiaxin Qian et al.
Huaiyu Yang et al.
Background: With the increasing prevalence of papillary thyroid carcinoma PTC) and advancements in auxiliary examination technology, the holistic detection rate of malignant thyroid nodules, particularly small ones, conti...
Case Report: Two cases of adrenal anastomosing hemangioma misdiagnosed as angiosarcoma [0.03%]
个例报道：2例肾上腺吻合血管瘤误诊为血管肉瘤病例报告
Dong-Lin He,Run-Lin Feng,Xin Guo et al.
Dong-Lin He et al.
Anastomosing hemangioma (AH) is a benign vascular tumor that has gradually been recognized in recent years, initially identified in the genitourinary tract. AH located in the adrenal gland is extremely rare, and the atypical preoperative sy...