Reporting of immune-related adverse events in US Food and Drug Administration approvals of immune checkpoint inhibitors [0.03%]
美国食品药品管理局批准的免疫检查点抑制剂中免疫相关不良事件的报告
Shaili Tapiavala,Chongliang Luo,Mina Shenouda et al.
Shaili Tapiavala et al.
Background: Predicting the occurrence of immune-related adverse events (irAEs) related to immune checkpoint inhibitors (ICI) is complex. Monitoring of irAEs is critical as toxicities cause morbidity and impact quality of ...
Zuzana Orszaghova,Beata Mladosievicova,Michal Mego et al.
Zuzana Orszaghova et al.
Introduction: Testicular germ cell tumors (TGCT) are highly curable malignancies, with excellent survival rates largely attributable to advances in cancer treatment. Consequently, there is a growing population of long-ter...
The impact of perioperative anesthesia management-induced immunosuppression on postoperative cancer recurrence and metastasis: a narrative review [0.03%]
围术期麻醉管理诱导的免疫抑制对术后癌症复发和转移的影响：综述
Yaxin Teng,Yanfang Yin,Yanan Shi et al.
Yaxin Teng et al.
Perioperative anesthesia management not only ensures safe and smooth surgery, but its potential immunomodulatory function has also triggered close attention from many researchers. Surgical/anesthetic drugs can cause immunosuppression charac...
The burden of thyroid cancer and its association with national development levels in Asia: evidence from 47 countries (1990-2021) [0.03%]
亚洲甲状腺癌的疾病负担及其与国家发展水平的关系(1990-2021年)：来自47个国家的证据
Wenyi Qin,Jiong Lin,Zhi Zhang et al.
Wenyi Qin et al.
Objective: This study examines the trends in thyroid cancer incidence and mortality and explores their relationship with national development levels. Meth...
Molecular mechanism of aerobic exercise in miRNAs and the anti-tumoral effects [0.03%]
有氧运动通过miRNA分子机制产生抗肿瘤效应的机理研究
Merve Çulha,Fabio S Lira,Jose C Rosa-Neto
Merve Çulha
Exercise decreases cancer risk, prevents recurrence and enhances treatment efficacy, however its exact mechanisms remain unclear. This review aims to (i) summarize the miRNAs released during aerobic exercise and explore the factors influenc...
Castleman disease with synchronous primary rectal and prostate cancers: a case report of successful multimodal treatment and 2-year recurrence-free survival [0.03%]
伴有同步原发直肠癌和前列腺癌的卡斯特尔曼病：一种成功的多模式治疗及无病生存两年的病例报告
Linhai Zheng,Mudan Lu,Yiming Liu et al.
Linhai Zheng et al.
Background: Castleman disease (CD) is a rare lymphoproliferative disorder associated with immune dysregulation that may increase the risk of malignancy. Synchronous multiple primary cancers are uncommon, and their etiolog...
Diagnostic value of ultrasonographic features in breast cancer and its correlation with hormone receptor expression [0.03%]
乳腺癌超声影像特征的诊断价值及其与激素受体表达的相关性
Jingzhou Yang,Xiaojuan Yu,Jianxin Liu
Jingzhou Yang
Introduction: The objective of this research is to investigate the diagnostic value of Ultrasonographic characteristics in breast cancer (BC) and its relation to hormone receptor status. ...
Karol Gawalski,Weronika Przybyszewska,Jaromir Hunia et al.
Karol Gawalski et al.
Messenger ribonucleic acid (mRNA) technology is a promising platform for cancer immunotherapy. Unlike traditional vaccines that prevent infectious diseases, mRNA's role in oncology is to stimulate or enhance the immune response against tumo...
Rectal spacer use and overall long-term healthcare costs: payer perspective [0.03%]
直肠隔舱器使用与长期整体医疗费用：支付方视角
James B Yu,Ryoko Sato,Michael R Folkert et al.
James B Yu et al.
Introduction: Rectal spacers (RS), when used in prostate cancer (PCa) patients treated with radiotherapy (RT), reduce radiation dose to the rectum. While RS incur additional upfront cost, they may result in long-term cost...
Analysis of the safety and efficacy of PD-1/PD-L1 inhibitors combined with chemotherapy in the treatment of locally advanced resectable esophageal squamous cell carcinoma: a systematic review and meta-analysis based on four randomized controlled trials [0.03%]
PD-1/PD-L1抑制剂联合化疗治疗局部晚期可切除食管鳞癌的安全性及有效性的系统评价和meta分析（基于4项随机对照试验）
Tao Luo,Hao Yang,Xingqiang Ran et al.
Tao Luo et al.
Background: Esophageal cancer is a leading type of cancer globally. Most patients diagnosed with esophageal cancer present at a locally advanced stage, for which the standard treatment paradigm involves a multimodal appro...