Establishment and validation of a prognostic model for nasopharyngeal carcinoma patients based on partial response rates [0.03%]
基于部分缓解率的鼻咽癌患者预后模型的建立及验证
Fujue Wang,Qiao Yang,Dong Yang et al.
Fujue Wang et al.
Objective: This study aims to investigate the impact of varying rates of partial response (PR) on survival outcomes in nasopharyngeal carcinoma (NPC) patients following induction chemotherapy (IC) and to develop a nomogra...
The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for the global burden of disease study 2021 [0.03%]
204个国家和地区1990年~2021年的结直肠癌疾病负担及其归因危险因素：2021年全球疾病负担研究的一项系统分析
Shen Tian,Yun-Shuai Wang,Dong Wei
Shen Tian
Background: Colorectal cancer (CRC) is among the leading causes of cancer-related mortality worldwide. This study aimed to assess the global burden of CRC across 204 countries and territories from 1990 to 2021, and identi...
Case Report: The crucial role of contrast-enhanced ultrasound and intraoperative ultrasound in diagnosing pediatric pancreatoblastoma [0.03%]
个例报告：对比增强超声和术中超声在儿童胰腺母细胞瘤诊断中起关键作用
Xiangfeng Zeng,Hualin Yan,Jiali Yang et al.
Xiangfeng Zeng et al.
Pancreatoblastoma (PB) is a rare malignant neoplasm of the pancreas, primarily affecting children. While some reports have described the imaging characteristics of PB, detailed descriptions of its ultrasound (US) and contrast-enhanced ultra...
Minimally invasive esophagectomy drives a decade-long decline in upper mediastinal recurrence after esophageal cancer surgery: a real-world, single-center cohort study [0.03%]
微创食管切除术驱动了食管癌术后上纵隔复发的十年下降：一项真实世界单中心队列研究
Shifa Zhang,Anhao Hu,Jiuhe Sun et al.
Shifa Zhang et al.
Background: Surgery is a cornerstone in the treatment of esophageal cancer, yet high postoperative recurrence rates remain a significant challenge. This study aimed to retrospectively examine the trends in postoperative r...
Construction and validation of a transmembrane 4 superfamily-related genes prognostic model for esophageal squamous cell carcinoma [0.03%]
基于跨膜蛋白4亚家族相关基因的食管鳞癌预后模型的构建及验证
Xin Hao,Hao Ding,Hongyu Zhu et al.
Xin Hao et al.
Background: Esophageal squamous cell carcinoma (ESCC), a virulent form of cancer, markedly diminishes prospects for patient survival. The transmembrane 4 superfamily (TM4SF)-related genes (TRGs) are instrumental in the ad...
Efficacy and safety of TACE/HAIC combined with targeted immunotherapy versus targeted immunotherapy for advanced hepatocellular carcinoma: a meta-analysis [0.03%]
经动脉化疗栓塞/肝动脉灌注化疗联合靶向免疫治疗与单纯靶向免疫治疗对比治疗晚期肝细胞癌的疗效和安全性：系统评价和Meta分析
Yuting Liao,Wenliang Zhu,Jianquan Zhang
Yuting Liao
Introduction: The purpose of this study was to investigate the efficacy and safety of triple therapy with transcatheter arterial chemoembolization (TACE)/hepatic arterial infusion chemotherapy (HAIC) in patients with adva...
Case Report: A case of necrotizing sarcoid granulomatosis mimicking metastatic tumor [0.03%]
个例报告：1例坏死性肉芽肿性 sarcoidosis 误诊为转移性肿瘤的病例报告
Lingjun Dong,Linhai Fu,Desheng Wei et al.
Lingjun Dong et al.
This article presents a case study of a patient with early-stage lung cancer who received comprehensive management at our institution throughout the entire clinical course. During follow-up, multiple progressively enlarging solid nodules we...
Metformin enhances alpelisib sensitivity in HER2+ breast cancer by suppressing cancer stemness and oncogenic signaling [0.03%]
二甲双胍通过抑制癌症干细胞特性及致癌信号转导增强阿培利塞对HER2阳性乳腺癌的敏感性
Yujie Shi,Peijia Niu,Qiong Cheng et al.
Yujie Shi et al.
Introduction: Alpelisib, a selective PI3Kα inhibitor that targets PIK3CA mutations, is approved for hormone receptor-positive, HER2-negative breast cancer. However, its therapeutic potential in HER2-positive disease rema...
Enhancing cancer risk awareness and screening management through artificial intelligence: a narrative review [0.03%]
人工智能在增强癌症风险意识和筛查管理方面的应用：综述研究
Jiaxuan Wu,Xiaolong Tang,Qian Zheng et al.
Jiaxuan Wu et al.
Cancer is a major public health problem worldwide, and early detection through risk awareness and screening is critical for improving patient outcomes. Although modern medicine has made certain progress, there are still many unmet clinical ...
CIK-augmented anti-PD1/CTLA4 immunotherapy eradicates chemo-resistant ovarian cancer via tripartite mechanistic synergy [0.03%]
携带cik的抗PD1 / CTLA4免疫疗法通过三重机制协同作用根除化疗耐药性卵巢癌
Peifang Chen,Jianrong Pan,Ling Chen et al.
Peifang Chen et al.
Background: Immune checkpoint inhibitors (ICIs) combined with adoptive cell therapy represent promising strategies against ovarian cancer, yet their synergistic mechanisms remain underexplored. This study evaluated the th...