Suppression of NK cell-mediated immunosurveillance by IL-35 drives tumor progression in EGFR-mutant non-small cell lung cancer [0.03%]
IL-35通过抑制NK细胞介导的免疫监视促进EGFR突变非小细胞肺癌进展
Na Li,YinSong Zhang,XiaoJie Zhang et al.
Na Li et al.
Background: Interleukin-35 (IL-35) is an added member of the IL-12 heterodimeric cytokine family, composed of two subunits: EBI3 and P35 subunits, implicated in tumor immune evasion. This study investigates the expression...
Pan-cancer analysis reveals ELFN1 as a novel prognostic biomarker and immunotherapeutic target associated with tumor microenvironment remodeling and promoting malignant phenotypes in colorectal cancer [0.03%]
泛癌分析揭示ELFN1是一种新的预后生物标志物和免疫治疗靶点，与结直肠癌肿瘤微环境重塑及促进恶性表型相关
Sha-Sha Hu,Tian-Yuan Tan,Wei Yan et al.
Sha-Sha Hu et al.
Background: Extracellular leucine rich repeat and fibronectin type III domain containing 1 (ELFN1), a transmembrane protein implicated in tumorigenesis and therapy resistance, remains mechanistically undefined as a pan-ca...
Clinical features and HLA typing of immune checkpoint inhibitor-associated myasthenia gravis, myocarditis and myositis [0.03%]
免疫检查点抑制剂相关重症肌无力、心肌炎和肌炎的临床特征和HLA分型
Xiaoting Lin,Peng Liu,Min Jin et al.
Xiaoting Lin et al.
Background: Immune checkpoint inhibitors (ICI) have significantly improved the therapeutic outcomes for various malignant tumors, but they may also trigger severe immune-related adverse events (irAEs), such as myositis, m...
Ruptured giant lateral thoracic meningocele associated with intracranial hypotension syndrome in neurofibromatosis type 1: case report with long-term follow-up [0.03%]
有关NF1患者并发颅内低压综合征的大胸侧脑膜膨出破裂的病例报告及长期随访结果
Wenfu Li,Hui Zhou
Wenfu Li
Lateral thoracic meningocele is a rare clinical entity typically associated with neurofibromatosis type 1 (NF1), which can progressively enlarge under the cerebrospinal fluid (CSF) pressure. Despite its rarity, these lesions may rupture or ...
A case report of tumor-associated liver injury alleviated with antineoplastic drug [0.03%]
抗肿瘤药物治疗相关的肿瘤性肝损伤一例报告
ZiRu Yang,Lixia Cao,Wentao Kuai et al.
ZiRu Yang et al.
Tumors are the major diseases that threaten people's health and life at present. Liver injury often happens in patients with cancer, and which mostly attribute to application of anti-cancer drugs. However, some cases caused by the infiltrat...
Deciphering the let-7c-5p/RRM2 axis in lung adenocarcinoma: expression, prognosis, and immune landscape implications [0.03%]
解码肺腺癌中let-7c-5p/RRM2轴：表达、预后和免疫景观意义
Jinlong Liu,Jinying Wu,Yu Han et al.
Jinlong Liu et al.
Objective: Lung adenocarcinoma (LUAD) is a subtype of non-small cell lung cancer with a poor prognosis. Ribonucleotide reductase subunit M2 (RRM2) has been implicated in the progression of various cancers, but its role in...
Gallbladder large cell neuroendocrine carcinoma in a patient with multiple myeloma: a case report and literature review [0.03%]
与多发性骨髓瘤相关的胆囊大细胞神经内分泌癌一例及文献复习
Yuhan Yin,Xinjie Dai,Dan Li et al.
Yuhan Yin et al.
Gallbladder Large Cell Neuroendocrine Carcinoma (GB-LCNEC), an extremely rare pathological subtype of gallbladder malignancies, is characterized by high aggressiveness and insidious onset, often leading to poor prognosis and presenting sign...
Nomogram for predicting risk of arm lymphedema following axillary lymph node dissection in breast cancer patients [0.03%]
乳腺癌腋窝淋巴结切除术后上肢淋巴水肿风险预测表
Miaomiao Jia,Lihui Pan,Haibo Yang et al.
Miaomiao Jia et al.
Purpose: Breast cancer-related arm lymphedema (BCRaL) is a prevalent and severe complication post-breast cancer treatment, especially following axillary lymph node dissection (ALND). This study aimed to develop a nomogram...
Long-term survival after solitary ocular metastasis following radical resection of esophagogastric junction carcinoma: a rare case report [0.03%]
食管胃交界部癌根治术后单发眼眶转移瘤的长期生存一例罕见个案报道
Yangjun Gao,Yuru Zhai,Ning Ma et al.
Yangjun Gao et al.
Background: Isolated ocular metastasis from esophagogastric junction (EGJ) cancer is extremely rare, and no standardized therapeutic approach has been established to date. Reporting such cases may help clarify optimal man...
Three-year of hepatocellular carcinoma surveillance in patients with cirrhosis diagnosed between 2009 and 2013: a cohort study based on the French National Health Data System (SNDS) claims data [0.03%]
2009年至2013年间诊断为肝硬化的患者三年内的肝细胞癌筛查：基于法国全民健康数据系统（SNDS）理赔数据的队列研究
Pascal Caillet,Fréderic Balusson,Nathalie Ganne-Carié et al.
Pascal Caillet et al.
Objectives: Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death worldwide. Most cases occur in patients with an underlying cirrhosis. The French national guidelines recommend semiannual abdo...