CT-based radiomics nomogram for differentiating dedifferentiated liposarcoma from well-differentiated liposarcoma [0.03%]
基于CT的影像组学预测模型在分化脂肪肉瘤和去分化脂肪肉瘤中的应用价值研究
Ting Yang,Ruo-Yu Chen,Yi-Fan Ding et al.
Ting Yang et al.
Purpose: This study aimed to use radiomics features derived from plain CT scans to construct a model that can predict the pathological classification of Retroperitoneal liposarcoma (RLPS) preoperatively, help enhance preo...
MicroRNAs and lung cancer: overview of essential pathways and somatic mutations in cancer progression [0.03%]
微小核糖核酸与肺癌：癌症进展中基本通路和体细胞性突变的综述
Andrei-Alexandru Tirpe,Andreea Nutu,Constantin Busuioc et al.
Andrei-Alexandru Tirpe et al.
Lung cancer is the most frequently diagnosed type of cancer worldwide, according to GLOBOCAN 2022 statistics. Key genetic alterations involve driver gene mutations that significantly enhance cancer aggressiveness. These include several EGFR...
Case Report: Failed response to anti-PD-1 immunotherapy in a colon cancer patient with high microsatellite instability [0.03%]
个案报告：一例高微卫星不稳定性结直肠癌患者抗PD-1免疫治疗无效
Rong Li,Yan-Ping Lin,Xin Shen et al.
Rong Li et al.
Background: Although immune checkpoint inhibitors (ICIs) have achieved remarkable progress in the treatment of deficient mismatch repair (dMMR)/high microsatellite instability (MSI-H) colorectal cancer (CRC), nearly 50% o...
Construction of a prognostic model for colorectal cancer liver metastasis based on single-cell transcriptomics and regulation of the MIF pathway [0.03%]
基于单细胞转录组学的结直肠癌肝转移预后模型构建及MIF通路调控作用分析
Jianqiang Cao,Zhaobin He,HuiJie Gao et al.
Jianqiang Cao et al.
Introduction: Colorectal cancer is associated with a generally poor prognosis, primarily due to its often late diagnosis and the high propensity for liver metastasis. Current treatment strategies emphasize personalized ap...
Downregulation of SALL1 and its association with poor prognosis and the immune cell landscape in clear cell renal cell carcinoma [0.03%]
SALL1下调及其与透明细胞肾细胞癌预后不良和免疫细胞景观的关系
Gen-Yi Qu,Shao-Hao Chen,Meng-Xin Liu et al.
Gen-Yi Qu et al.
Background: Spalt-like transcription factor 1 (SALL1), a member of the Krüppel-associated box-containing zinc finger proteins, has been implicated in tumor suppression, epigenetic regulation, and immune modulation in sev...
Case Report: Ovarian endometrioid tumor occurring in a patient with early-stage, low-risk endometrial carcinoma successfully treated by fertility-sparing management [0.03%]
个案报道：早期低风险子宫内膜癌患者成功采用生育保留手术治疗合并卵巢内膜样肿瘤
Shuxu Tian,Huangbei Song,Fang Wang et al.
Shuxu Tian et al.
Rationale: Endometrial carcinoma (EC) increasingly affects younger women, prompting interest in fertility-sparing treatments. Although hormonal therapy is a feasible option for carefully selected patients, there remains a...
Efficacy and safety of antibody-drug conjugate combination therapy in advanced urothelial carcinoma [0.03%]
抗体偶联药物联合治疗晚期尿路上皮癌的疗效和安全性评估研究
Salvador Jaime-Casas,Regina Barragan-Carrillo,Miguel Zugman et al.
Salvador Jaime-Casas et al.
Antibody-drug conjugates (ADCs) are revolutionizing the treatment landscape of advanced urothelial carcinoma (aUC). We systematically reviewed the PubMed and Embase databases for published clinical trials evaluating ADC-combination regimens...
Case Report: Successful treatment of a case of Lynch syndrome with double primary ovarian and rectal cancer [0.03%]
利氏综合症合并卵巢及直肠双原发肿瘤一例报告
Zhengliang Yu,Gang Yang,Jing Yue et al.
Zhengliang Yu et al.
Background: Lynch syndrome (LS), previously known as hereditary nonpolyposis colorectal cancer (CRC), is an autosomal dominant disorder characterized by germline variants in the mismatch repair (MMR) gene (e.g., MLH1 and ...
Preprocedural computed tomography angiography-guided transcatheter arterial embolization for managing esophageal cancer bleeding: a case series study [0.03%]
基于前期CTA的食管癌出血介入治疗栓塞术单中心系列病例报告
Xue-Jiao Yang,Yong-Juan Wu,Jing-Zhong Wang et al.
Xue-Jiao Yang et al.
Objective: While endoscopy is the first-line treatment for non-variceal upper gastrointestinal hemorrhage, its role in managing upper gastrointestinal tumor bleeding is limited. This study aims to evaluate the effect of c...
Trends in liver cancer burden in China and G20: a comparative analysis using GBD 2021 [0.03%]
基于GBD 2021的中国和G20国家肝癌疾病负担变化趋势比较分析
Xiaodi Ma,Lining Jiang,Bing Han et al.
Xiaodi Ma et al.
Objective: To compare liver cancer trends and risk factors in China with those in G20 countries (1990-2021) to inform prevention and resource allocation. ...