Unveiling the impact of lipid metabolism on triple-negative breast cancer growth and treatment options [0.03%]
脂质代谢对三阴性乳腺癌生长及治疗选择的影响研究
Xin-Xian Cai,Zhe-Zhong Zhang,Xiao-Xiao Yang et al.
Xin-Xian Cai et al.
Triple-negative breast cancer (TNBC) is a subtype of breast cancer associated with poor prognosis and limited targeted treatment options. Lipid metabolism plays a pivotal role in the initiation, progression, and metastasis of TNBC by suppor...
TFRC promotes the proliferation, migration, and invasion of osteosarcoma cells by increasing the intracellular iron content and RRM2 expression [0.03%]
TFRC通过增加细胞内铁含量和RRM2表达促进骨肉瘤细胞的增殖、迁移和侵袭能力
Guoqing Ren,Jian Zhou,Yong Su et al.
Guoqing Ren et al.
Background: Multiple studies have shown that the transferrin receptor (TFRC) is highly expressed in various tumors, and it has been recognized as a cancer biomarker. However, its role in osteosarcoma(OS) has rarely been s...
Senescence-associated secretory phenotype in lung cancer: remodeling the tumor microenvironment for metastasis and immune suppression [0.03%]
衰老相关分泌表型与肺癌微环境重塑及转移和免疫抑制的关系
Chen Chen,Ji Chen,Yanling Zhang et al.
Chen Chen et al.
Cellular senescence exerts dual roles in lung cancer pathogenesis: initially suppressing tumorigenesis via p53/p21/p16-mediated cell cycle arrest, but promoting malignancy through the senescence-associated secretory phenotype (SASP). SASP s...
Efficacy and safety of inetetamab-containing regimens in patients with HER2-positive metastatic breast cancer in first-line/second-line setting [0.03%]
伊尼妥单抗联合化疗用于HER2阳性转移性乳腺癌患者一线和二线治疗的有效性和安全性：一项系统评价和 meta 分析
Jian Zhang,Yuxin Mu,Hui Zhang et al.
Jian Zhang et al.
Background: Inetetamab is a novel recombinant humanized anti-Human epidermal growth factor receptor 2 (HER2) monoclonal antibody. This real-world retrospective study assessed the efficacy and safety of inetetamab-containi...
Advancing targeted therapy for colorectal cancer: harnessing ligand-directed enzyme prodrug therapy for highly specific interventions [0.03%]
结直肠癌精准治疗策略的研究进展：基于配体指导的酶前药系统实现特定肿瘤组织的精准介入治疗
Hend Al-Jaber,Kabir H Biswas,Layla Al-Mansoori
Hend Al-Jaber
Colorectal cancer (CRC) is a significant global health burden, ranking as the third most frequently diagnosed cancer and a leading cause of cancer-related mortality. Current therapeutic modalities face challenges in advanced stages, includi...
Clinical features and mutational frequency of renal cell carcinoma from patients undergoing kidney transplant evaluation [0.03%]
肾脏活检来源的肾细胞癌临床特点及突变频率分析
Corbin J Eule,Junxiao Hu,Kurtis D Davies et al.
Corbin J Eule et al.
Background: Patients with chronic kidney disease (CKD) or post-kidney transplant have an elevated risk of renal cell carcinoma (RCC). Despite increased understanding of genomic alterations in clear cell and papillary RCC,...
Fertility-sparing surgery in primary peritoneal serous borderline tumor: a case report [0.03%]
原发性腹膜浆液性交界性肿瘤的保留生育功能手术1例报告
Tingting Li,Wei Jiang,Hongjing Wang
Tingting Li
Primary peritoneal serous borderline tumor (PPSBT) is a rare, low-malignant-potential neoplasm arising from the peritoneum, diagnosed only after excluding ovarian involvement. While typically discovered incidentally during surgery, it often...
Leaf-vein-inspired multi-organ microfluidic chip for modeling breast cancer CTC organotropism [0.03%]
叶脉启发的多器官微流控芯片，可模拟乳腺癌细胞转移器官特异性行为
Liuyin Liu,Xiaoli Qu,Zhe Wang et al.
Liuyin Liu et al.
Objective: Breast cancer is characterized by a high tendency for organ-specific metastasis. This study aims to develop a multi-organ metastasis model for circulating tumor cells (CTCs) of breast cancer to explore their or...
Association between examined lymph node count and survival in resectable cervical cancer: a retrospective analysis using SEER data [0.03%]
基于SEER数据库的可手术宫颈癌患者受检淋巴结数目与生存期的关系研究：一项回顾性分析
Jing Gao,Wanchun Yin,Zhiqing Zhang et al.
Jing Gao et al.
Background: The optimal examined lymph node (ELN) in resectable nonmetastatic cervical cancer patients remains controversial. Methods: ...
Knowledge mapping of global trends in DNA damage repair-related breast cancer research: a bibliometric study [0.03%]
基于文献计量的DNA损伤修复相关乳腺癌研究全球趋势知识图谱分析
Yajing Huang,Shumei Wei,Kaimin Hu et al.
Yajing Huang et al.
Background: Breast cancer remains one of the leading causes of cancer-related morbidity and mortality among women worldwide. Recent advancements in our understanding of DNA damage repair (DDR) mechanisms have shed light o...