The potential clinical significance of immunomodulation of immune and inflammatory responses involving selected adipokines in patients with ovarian cancer - preliminary studies [0.03%]
Sebastian Stępień,Maria-Laura Morawiec,Marta Smycz-Kubańska et al.
Sebastian Stępień et al.
Ovarian cancer (OC) is a major clinical problem in gynaecological oncology, characterised by difficulties in early diagnosis, which contributes to the high mortality rate from OC. Therefore, the search for new biological markers continues, ...
Long-term complete remission of metastatic combined hepatocellular-cholangiocarcinoma with nivolumab following failure of targeted therapies: a case report [0.03%]
Young Mi Hong
Young Mi Hong
Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare and aggressive primary liver malignancy with limited treatment options and poor prognosis. We report the case of 33-year-old male with chronic hepatitis B who underwent hepatec...
Salvage definitive or hypofractionated radiotherapy for oligometastatic recurrence after durvalumab consolidation in limited-stage small-cell lung cancer: a two-case report [0.03%]
Jiahui Shan,Jiayi Yu,Dan Yang et al.
Jiahui Shan et al.
The ADRIATIC trial demonstrated that consolidation durvalumab after concurrent chemoradiotherapy (cCRT) improves progression-free survival (PFS) and overall survival (OS) in limited-stage small cell lung cancer (LS-SCLC), establishing a new...
Sixian Wang,Hao Xiao,Huafang Gao
Sixian Wang
Introduction: Despite advancements in cervical cancer early detection, such as HPV screening, their inherent limitations, such as unsatisfactory specificity, necessitate the discovery of novel, highly accurate biomarkers ...
Stent or stoma as a bridge to surgery in patients with acute malignant colorectal obstruction: a comparison of oncologic long-term results [0.03%]
Johannes Asplund,Gabriel Sandblom,Isalee Jallow Göransson et al.
Johannes Asplund et al.
Purpose: To evaluate the long-term oncologic results in patients treated for malignant left-sided colorectal obstruction with colonic stent or a deviating stoma as bridge to surgery. ...
A histopathology image-based computer-aided classification study for oral squamous cell carcinoma [0.03%]
Yiping Ren,Runwen Li,Dong Chen
Yiping Ren
Introduction: Oral squamous cell carcinoma histopathological image classification is often challenged by staining variations and sparse local lesions, which can cause models to overfit color differences and weaken cross-d...
Case Report: Rare gastric and bone metastases after early endocrine therapy discontinuation in hormone receptor-positive breast cancer: lessons and therapeutic insights [0.03%]
Minjun Lu,Guinv Hu,Qinyan Shen
Minjun Lu
Breast cancer with gastric metastasis is extremely rare. Non-persistence with adjuvant endocrine therapy is associated with increased recurrence/metastasis risk in hormone receptor-positive (HR+) breast cancer. A 33-year-old female was init...
Case Report: Sustained complete response achieved in a patient with advanced HER-2 positive gastric cancer after 4 years of chemotherapy-free treatment [0.03%]
Xinyu Tong,Jieqiong Peng,Bo Liu
Xinyu Tong
Background: Gastric cancer ranks fifth in both global incidence and mortality rates, with over half of the newly diagnosed cases worldwide occurring in China. Most patients are diagnosed at advanced stages, making surgica...
Exploring the pharmacological mechanisms of resibufogenin in castration-resistant prostate cancer via network pharmacology and experimental validation [0.03%]
Yuanxin Xing,Lu Xiang,Yanfei Jia et al.
Yuanxin Xing et al.
Background: Resibufogenin (RBG) has shown anti-tumor effects in many cancers, but its role and mechanism in castration-resistant prostate cancer (CRPC) are still unclear. ...
Safety and efficacy of PEG-rhG-CSF as primary prophylaxis for neutropenia in gastrointestinal cancer patients receiving combination chemotherapy including oral agents: a prospective, exploratory, non-randomized controlled study [0.03%]
Hui Wang,Xiaoling Zhang,Yunyi Du et al.
Hui Wang et al.
Purpose: The safety and efficacy of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) for prevention of chemotherapy-induced neutropenia (CIN) in patients undergoing oral chemotherapy remain ...
Clinical Trial
Frontiers in oncology. 2026 Apr 14:16:1764358. DOI:10.3389/fonc.2026.1764358 2026