Relapse in childhood B-cell precursor acute lymphoblastic leukemia: insights from transcriptomic signatures of diagnostic bone marrow [0.03%]
儿童前体B细胞急性淋巴细胞白血病复发：来自诊断骨髓转录特征的启示
Lixian Oh,Mohamad Shafiq Azanan,Hany Ariffin
Lixian Oh
Survival rates exceeding 85% are now achieved for most children diagnosed with B-cell precursor acute lymphoblastic leukemia (BCP-ALL), the most common subtype of childhood ALL. Advances in the understanding of disease biology, the identifi...
A rare initial presentation of giant pheochromocytoma: a case report of acute pulmonary embolism complicated by catecholamine-induced cardiomyopathy [0.03%]
巨大嗜铬细胞瘤的罕见初始表现：儿茶酚胺性心肌病并急性肺栓塞1例报告
Lujing Zhao,Yanqing Zhang,Yu Zhou et al.
Lujing Zhao et al.
Pheochromocytoma is a rare neuroendocrine tumor characterized by excessive catecholamine secretion, typically presenting with hypertension, headache, palpitations, and sweating. Giant pheochromocytomas (commonly defined as tumors with diame...
All-trans retinoic acid combined with the VAH regimen for EVI1-positive acute myeloid leukemia: a case report with a brief literature review [0.03%]
全反式维甲酸联合VAH方案治疗EVI1阳性急性髓系白血病一例并文献回顾
Yingxin Zhao,Hongxia Wang,Jiaxin Lv et al.
Yingxin Zhao et al.
EVI1 positivity is a well-recognized high-risk factor in acute myeloid leukemia (AML), typically characterized by complex molecular genetic abnormalities, suboptimal responses to conventional chemotherapy, and a poor prognosis. We report a ...
Breast-conserving surgery after vacuum-assisted biopsy in patients with unexpected breast cancer: is it reliable? A 5-year follow-up study [0.03%]
真空辅助活检后意外发现乳腺癌患者保乳手术的可靠性研究——一项5年随访研究
Hong-Yan Fang,Wen-Ting Zheng,Yang-Jun Cai et al.
Hong-Yan Fang et al.
Background: Vacuum-assisted breast biopsy (VABB) is commonly used for complete resection of benign tumors and diagnostic biopsy of suspected malignant tumors in China. Post-procedural hematoma formation may potentially fa...
Proteogenomic detection of tumor-specific somatic mutant proteins in urinary extracellular vesicles for non-invasive monitoring of bladder cancer [0.03%]
基于尿液外泌体肿瘤特异性体细胞突变蛋白的泌尿系肿瘤精准液体活检研究
Yuji Hakozaki,Kazuma Sugimoto,Yuta Yamada et al.
Yuji Hakozaki et al.
Background: Non-muscle invasive bladder cancer (NMIBC) is characterized by frequent recurrence, requiring repeated cystoscopic surveillance that is invasive and burdensome for patients. Although liquid biopsy approaches h...
Case report: Technical risk mitigation and management strategies of semi-implantable intrathecal drug delivery systems for advanced cancer pain: a case-based study [0.03%]
个例报道：晚期癌痛半植入式鞘内镇痛系统技术风险管理及策略：基于病例的研究
Yi Lu,Yujia Xie,Xinyao Ye et al.
Yi Lu et al.
Objective: This study investigated the clinical efficacy, technical risks, and management strategies of the semi-implantable intrathecal drug delivery system (IDDS) as a "fourth-step" analgesic regimen for refractory adva...
Case Report: Interpectoral lymph node metastasis as an indicator of occult breast cancer: a case of double primary malignancy [0.03%]
案例报告：间隔淋巴结转移作为潜在乳腺癌指标的双原发恶性肿瘤病例
Qian Zhao,Yangxuzhu Liu,Yifan Fu et al.
Qian Zhao et al.
Occult breast cancer (OBC) is a rare clinical entity, characterized by the presence of metastatic adenocarcinoma in the axillary lymph nodes without an identifiable primary tumor in the breast. We present an unprecedented case of synchronou...
Construction and validation of a multimodal MRI-based deep learning model for early differential diagnosis of prostate cancer in the PSA gray zone: a retrospective cohort study [0.03%]
基于多模态MRI的深度学习模型在前列腺灰区诊断前列腺癌的构建和验证：回顾性队列研究
Zuliang Xu,Dabin Ren,Guoyu Wang et al.
Zuliang Xu et al.
Background: The diagnostic challenges inherent in prostate-specific antigen (PSA) levels between 4-10 ng/mL represent a critical clinical dilemma, with only 25-30% of patients harboring clinically significant prostate can...
A fusion model based on tumor and peritumoral CT radiomics for differentiating bronchiolar adenoma from lung adenocarcinoma [0.03%]
基于肿瘤和瘤周CT影像组学的融合模型鉴别支气管腺瘤与肺腺癌
Ziqian Zhao,Tengfei Ke,Zeyan Xu et al.
Ziqian Zhao et al.
Purpose: This study aimed to develop and validate a combined clinical and tumor-peritumoral CT radiomics model to differentiate bronchiolar adenoma (BA) from lung adenocarcinoma (LUAD), thereby improving preoperative diag...
Isolated central nervous system involvement in blastic plasmacytoid dendritic cell neoplasm: a rare case of relapse during systemic remission with diagnostic and therapeutic implications [0.03%]
孤立性中枢神经系统浆细胞样树突状细胞肿瘤受累：系统性疾病缓解期罕见复发病例的诊断和治疗意义
Haocheng Zhao,Wenye Huang,Shanshan Lin et al.
Haocheng Zhao et al.
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, highly aggressive hematologic malignancy characterized by frequent involvement of the skin and bone marrow. Central nervous system (CNS) infiltration is uncommon and may be cli...