Context-dependent rewiring of dual-function proteins in cancer: a sequential strategy to restore apoptosis [0.03%]
癌症中具有双重功能蛋白质的条件依赖性重构：恢复凋亡的顺序策略
Leon Strzadala
Leon Strzadala
Resistance to programmed cell death is a defining hallmark of cancer and a persistent barrier to successful therapy. Dual-function proteins such as p53, Ras, HIF-1α, BNIP3, and NF-κB act as molecular switches that determine cell fate betw...
Wentao Xie,Xinye Jiang,Jingying Huang et al.
Wentao Xie et al.
Acute myeloid leukemia (AML) is a highly heterogeneous malignant hematological neoplasm. Although standard diagnostic procedures have been established, traditional methods still face limitations with regard to efficiency, accuracy, and stan...
Unraveling the role of coagulation-related genes in esophageal squamous cell carcinoma: development of a prognostic model and exploration of potential clinical significance [0.03%]
凝血相关基因在食管鳞癌中的作用及预后模型的建立与临床意义探索
Langlang Deng,Chen Fang,Weiran Zhang et al.
Langlang Deng et al.
Background: Esophageal squamous cell carcinoma (ESCC), the most common form of esophageal cancer, is associated with high incidence and mortality rates, representing a major public health challenge. Although previous rese...
Case Report: Uncommon co-occurrence of different renal histopathological entities in a patient with multiple myeloma and lymphoplasmacytic lymphoma [0.03%]
个案报告：多发性骨髓瘤和淋巴浆细胞淋巴瘤患者的罕见共病肾脏活检结果病理实体病例
Marco Talarico,Gisella Vischini,Simona Barbato et al.
Marco Talarico et al.
In patients with plasma cell dyscrasias presenting with kidney injury, renal biopsy usually displays the presence of a single histological damage. However, the coexistence of heterogeneous damages has been occasionally described and is asso...
Evaluating the impact of different deface algorithms on deep learning segmentation software performance [0.03%]
不同擦除算法对深度学习分割软件性能影响的评估
Ali Ammar,Libing Zhu,Shep Bryan th et al.
Ali Ammar et al.
Introduction: Data sharing is essential for advancing research in radiation oncology, particularly for training artificial intelligence (AI) models in medical imaging. However, privacy concerns necessitate de-identificati...
Global, regional, and national burden of lung cancer attributable to second-hand smoke from 1990 to 2021: a systematic analysis based on the Global Burden of Disease Study 2021 [0.03%]
1990年至2021年全球、区域和国家归因于二手烟的肺癌负担：基于2021年全球疾病负担研究的系统分析
Zheng Zhang,Xiao-Hui Zhang,Rong Huang et al.
Zheng Zhang et al.
Introduction: Second-hand smoke (SHS) exposure significantly contributes to lung cancer development, yet its global burden remains poorly quantified. Meth...
MRI management of focal liver lesions: what a beginner cannot fail to know [0.03%]
磁共振肝占位性病变的诊断与鉴别诊断——不可不知的要点
Vincenza Granata,Roberta Fusco,Igino Simonetti et al.
Vincenza Granata et al.
Magnetic resonance imaging (MRI) is currently recognized as the most suitable diagnostic tool for the detection and characterization of focal liver lesions. The combination of morphological and functional data allows, in different clinical ...
A scientometric analysis of global research on gut microbiota and glioma [0.03%]
全球肠道微生物与胶质瘤研究的科学计量分析
Lize Chen,Kun Shu,Zhiyin Zhang et al.
Lize Chen et al.
Background: Most previous studies have demonstrated that gut microbiota is closely related to the prognosis of glioma. However, there is currently no corresponding bibliometric analysis to systematically review, analyze, ...
Comparative safety and efficacy of tislelizumab-based regimens versus chemotherapy in lung cancer: a systematic review and meta-analysis [0.03%]
替雷利珠单抗与化疗在肺癌中安全性和有效性的比较：系统评价和Meta分析
Aman Ullah,Faseeh Haider,Faizan Ahmed et al.
Aman Ullah et al.
Background: Lung cancer is the leading cause of cancer-related mortality worldwide, with its burden expected to rise significantly by 2025. Despite therapeutic advances, survival rates remain low, and comorbidities furthe...