The rare report of unicentric Castleman disease with concurrent myasthenia gravis and paraneoplastic pemphigus: a case report with a focused review of the literature [0.03%]
原发性单纯型卡斯特尔曼病并发重症肌无力和副肿瘤性天疱疮的罕见病例报告及文献回顾式讨论
Zeyu Cheng,Wenliang Liu,Yan Hu
Zeyu Cheng
Rationale: Castleman disease (CD) is a rare lymphoproliferative disorder that can be associated with autoimmune manifestations. While paraneoplastic pemphigus (PNP) and myasthenia gravis (MG) have each been reported with ...
A deep learning-based automatic segmentation model for diffuse midline glioma with H3K27M alteration [0.03%]
基于深度学习的弥漫内生性桥脑胶质瘤（H3K27M改变型）自动分割模型
Yong Deng,Tengyun Chen,Yuekang Zhang et al.
Yong Deng et al.
Background: Diffuse midline glioma (DMG) is a fatal tumor that emerges in the brainstem and thalamus. Compared with microsurgery and chemotherapy, radiotherapy is currently regarded as a safer and more effective treatment...
Case Report: Novel molecular characterization of rare primary mucinous adenocarcinoma of the renal pelvis [0.03%]
病例报告：罕见原发性肾盂粘液腺癌的新型分子特征鉴定
Megan K Taylor,Irasema C Paster,Dory E Arevelo Salazar et al.
Megan K Taylor et al.
Mucinous adenocarcinoma of the renal pelvis (MAC-RP) is an exceedingly rare condition, accounting for less than 1% of malignancies originating from this epithelial site. We report a case of MAC-RP in a woman presenting with right flank pain...
Clinical application of confocal laser endomicroscopy in the diagnosis of malignant pleural effusion [0.03%]
共聚焦激光内镜在恶性胸腔积液诊断中临床应用
Shenglan Ye,Mingli Yuan,Cheng Song et al.
Shenglan Ye et al.
Objective: Probe-based confocal laser endomicroscopy (pCLE) is an innovative in vivo microscopic imaging technique that enables real-time visualization of tissue cytology during endoscopic examinations. This study aimed t...
Adenoid cystic carcinoma of the external auditory canal with metastasis to the cerebellopontine angle mimicking vestibular schwannoma: a case report and literature review [0.03%]
外耳道腺样囊性癌伴桥小脑角转移误诊为听神经瘤的病例报告及文献复习
Zhifei Guo,Jie He,Xiangyu Zhang et al.
Zhifei Guo et al.
Purpose/aim: Adenoid cystic carcinoma (ACC) of the external auditory canal (EAC) is a rare malignancy with a propensity for perineural invasion and distant metastasis. Its metastasis to the cerebellopontine angle (CPA) ha...
Liquid biopsy in triple-negative breast cancer: a promising tool for diagnosis, prognosis, and treatment monitoring [0.03%]
循环肿瘤细胞和ctDNA在三阴性乳腺癌中的应用前景
Marianna Rita Brogna,Gerardo Ferrara,Valeria Varone et al.
Marianna Rita Brogna et al.
Triple-negative breast cancer (TNBC) is a highly aggressive and heterogeneous subtype of breast cancer, characterized by poor prognosis and limited treatment options. With the advancements in precision oncology, liquid biopsy has emerged as...
Headache as the initial symptom in two cases of multiple myeloma: a case report and literature review [0.03%]
以头痛为首发症状的两例多发性骨髓瘤病例报道及文献复习
Denglu Liu,Minghui Du,Xiaoyu Gao
Denglu Liu
Multiple myeloma (MM) is a hematologic malignancy characterized by clonal proliferation of plasma cells. It typically manifests with bone pain, renal failure, anemia, and hypercalcemia. However, initial presentations can be atypical, potent...
Integrative subtyping by bile acid metabolism identifies CLCA1/ UGT2A3/ ZG16 as markers of immune dysfunction and poor prognosis in colorectal cancer [0.03%]
胆汁酸代谢整合亚型分析鉴定出CLCA1 / UGT2A3 / ZG16是免疫功能障碍和结直肠癌预后不良的标志物
Li Feng,Min Wang,Xin Li et al.
Li Feng et al.
Background: Colorectal cancer (CRC) is the primary driver of cancer-related death and illness across the world. Despite the full-scale shift of the treatment approach for some colorectal cancer patients due to the use of ...
Case Report: Postmenopausal hyperandrogenism misled by adrenal incidentaloma: a rare case of androgen-secreting ovarian adult granulosa cell tumor and clinical implications [0.03%]
个例报道：肾上腺意外瘤误导的绝经后高雄激素血症——卵巢成人颗粒细胞瘤罕见病例及其临床意义
Conghui Cao,Xiaoli Wang
Conghui Cao
Background: Ovarian adult-type granulosa cell tumors (AGCTs) are rare sex cord-stromal neoplasms, accounting for 95% of ovarian granulosa cell tumors (GCTs) but only 10% of which secrete androgens. For postmenopausal wome...
Real-world clinical characteristics and outcomes of patients with locally advanced, unresectable esophageal/gastroesophageal junction cancer treated with definitive chemoradiotherapy in the United States community oncology setting [0.03%]
美国社区肿瘤环境中 definitive 化疗联合放疗治疗局部晚期、不可切除的食管/胃食管结合部癌患者的临床特征和结果
Adriana Valderrama,Karthik Ramakrishnan,Lisa Herms et al.
Adriana Valderrama et al.
Introduction: There are limited real-world data describing treatment patterns and clinical outcomes for patients with locally advanced, unresectable esophageal and gastroesophageal junction cancer (EC/GEJC) treated with d...