IGF2BP3 enhances ferroptosis resistance in colon cancer by stabilizing SLC7A11 and is regulated by miR-98-5p [0.03%]
结肠癌中IGF2BP3通过稳定SLC7A11增强铁死亡抵抗并受miR-98-5p调节
Yaya Sun,Qingwei Liu,Junjie Wu et al.
Yaya Sun et al.
Purpose: Colon cancer remains a global health challenge with rising mortality, necessitating novel therapeutic strategies. IGF2BP3, an oncogenic RNA-binding protein, is implicated in colon cancer progression, while its ro...
A reduced-toxicity myeloablative conditioning approach for hematopoietic cell transplant in juvenile myelomonocytic leukemia [0.03%]
用于幼年型粒单核细胞白血病造血细胞移植的减毒清髓性预处理方案
Eman Elsabagh,Rachel Gallant,Lior Goldberg et al.
Eman Elsabagh et al.
Introduction: Allogeneic hematopoietic cell transplantation (HCT) is a potentially curative treatment for most children with juvenile myelomonocytic leukemia (JMML), but overall survival remains poor at 50%. Given its rar...
Linxiao Gao,Bing Tu,Mingxiang Cheng et al.
Linxiao Gao et al.
Posthepatectomy liver failure (PHLF) is one of the most harmful complications after liver resection. Here, we report a case of a specific type of PHLF in a 60-year-old man with hepatocellular carcinoma. The patient developed extensive liver...
Corrigendum: Differentiation of early-stage tumors from benign lesions manifesting as pure ground-glass nodule: a clinical prediction study based on AI-derived quantitative parameters [0.03%]
基于AI衍生的定量参数鉴别早期肿瘤与纯磨玻璃结节良性病变的临床预测研究更正通知书
Shuxiang Chen,Huijuan Zhang,Yifan Chen et al.
Shuxiang Chen et al.
[This corrects the article DOI: 10.3389/fonc.2025.1573735.]. Keywords: AI; CT; benignity; identification; lu...
Published Erratum
Frontiers in oncology. 2025 Jun 3:15:1631465. DOI:10.3389/fonc.2025.1631465 2025
Reducing unnecessary biopsies of BI-RADS 4 lesions based on a deep learning model for mammography [0.03%]
基于乳腺X线摄影的深度学习模型减少BI-RADS 4类病变不必要的活检
Yuting Yang,Tingting Liao,Xiaohui Lin et al.
Yuting Yang et al.
Objective: In this study, we aimed to explore the diagnostic value of a deep learning (DL) model based on mammography for Breast Imaging Reporting and Data System (BI-RADS) 4 lesions and to reduce unnecessary breast biops...
The value analysis of tumor deposit in the comprehensive evaluation before differentiated thyroid cancer RAI therapy [0.03%]
分化型甲状腺癌RAI治疗前综合评估中肿瘤沉积的价值分析
Lei Wang,Jing Yang,Yuan Zhu et al.
Lei Wang et al.
Objective: This study aimed to investigate the impact of tumor deposit (TD) on Radioiodine (RAI) therapy efficacy in Differentiated Thyroid Cancer (DTC) and explore their potential role in postoperative staging and the Am...
The regulatory network of epithelial-mesenchymal transition-associated non-coding RNAs in thyroid cancer: molecular mechanisms, clinical implications, and therapeutic strategies [0.03%]
与甲状腺癌上皮间质转化相关的非编码RNA的调控网络：分子机制、临床意义和治疗策略
Rui Zhao,Jiaju Tian,Jing Peng et al.
Rui Zhao et al.
Thyroid cancer represents the most prevalent malignant neoplasm within the endocrine system, exhibiting a steadily increasing global incidence. Non-coding RNAs (ncRNAs) have emerged as a pivotal focus in thyroid cancer research, demonstrati...
Adeno-associated virus vector modification based on directed evolution technology for gene therapy targeting head and neck squamous cell carcinoma [0.03%]
基于定向进化技术的腺相关病毒载体改造在头颈鳞癌基因治疗中的应用研究
Yiyuan Zhu,Wei Ji,Qi Zhang et al.
Yiyuan Zhu et al.
Introduction: Adeno-associated virus (AAV) vectors are promising tools for cancer gene therapy, yet their clinical application in head and neck squamous cell carcinoma (HNSCC) is hindered by suboptimal transduction effici...
MS-stable/TMB-high pleomorphic liposarcoma successfully treated with pembrolizumab: a case report [0.03%]
帕博利珠单抗成功治疗MS不稳定型/肿瘤突变负荷高型多形性脂肪肉瘤1例报告
Satoshi Miwa,Hiroshi Kobayashi,Toshihide Hirai et al.
Satoshi Miwa et al.
Pleomorphic liposarcoma (PLPS) is a rare and aggressive subtype of liposarcoma with limited treatment options. Despite studies on immune checkpoint inhibitors (ICIs) in sarcomas, there have been few reports involving PLPS. Furthermore, the ...
Two decades of progress in gastric cancer peritoneal metastasis: a bibliometric perspective on molecular mechanisms and therapeutic innovations [0.03%]
胃癌腹膜转移的二十年进步：分子机制和治疗创新的文献计量学视角
Jin Qian,Xiaoxuan Tu,Jianglin Chen et al.
Jin Qian et al.
Background: Gastric cancer (GC) is the fifth most common malignant tumor worldwide. The peritoneum is a common site of metastasis in advanced GC, and patients with gastric cancer peritoneal metastasis (GCPM) have a very l...