Aggressive evolution of an occipital bone ABC-like lesion with dural invasion and intradural extension: a case report [0.03%]
一例枕骨ABC样病变伴硬脑膜侵犯及硬膜内延伸的侵袭性进展病例报告
Xiaoman Shi,Xinyuejia Huang,Hao Deng et al.
Xiaoman Shi et al.
Background: Aneurysmal bone cysts (ABCs) of the skull are rare, particularly those arising in the occipital bone. Intracranial extension or dural destruction is extremely uncommon. Here, we report an occipital ABC-like le...
Multimodal artificial intelligence in glioma management: integrating neuroimaging and hematologic biomarkers for precision oncology [0.03%]
多模态人工智能在胶质瘤管理中的应用：整合神经影像和血液生物标志物以实现精准肿瘤学
Rafail C Christodoulou,Platon S Papageorgiou,Daniel Eller et al.
Rafail C Christodoulou et al.
Background: Gliomas are biologically heterogeneous primary brain tumors that remain challenging to diagnose, prognosticate, and monitor noninvasively, owing to marked intratumoral heterogeneity, treatment-related imaging ...
Accessibility to molecular studies in gliomas: a challenge for precision medicine in low-resource countries [0.03%]
低资源国家胶质瘤精准医疗面临的分子研究挑战
Pablo S Paolinelli,Tomas Saavedra Azcona,Florencia B Casto et al.
Pablo S Paolinelli et al.
CNS tumors present significant diagnostic challenges due to their heterogeneity. Successive editions of the World Health Organization (WHO) classification have progressively incorporated molecular markers as essential criteria. Nonetheless,...
Case Report: Use of mirvetuximab soravtansine in a patient with platinum-resistant ovarian cancer and concomitant PARP-inhibitor-related myelodysplastic syndrome [0.03%]
病例报告：mirvetuximab soravtansine在铂耐药型卵巢癌合并聚腺苷二磷酸核糖聚合酶抑制剂相关性骨髓形态异常综合征患者中的应用
Sophonie Shilonite Njonou Noujiep,Judith Altmann,Lars Bullinger et al.
Sophonie Shilonite Njonou Noujiep et al.
Response rates in platinum-resistant ovarian cancer remain low (16-30%) and decline with subsequent lines of therapy. Mirvetuximab soravtansine (MIRV), an antibody-drug conjugate targeting folate receptor alpha (FRα), has demonstrated clin...
PAMAM dendrimers as efficient drug nanocarriers of natural compounds in breast cancer therapeutics [0.03%]
天然化合物在乳腺癌治疗中的药物纳米载体潘胺树状分子研究
Syed Gulfishan,Mir Waqas Alam,Pratibha Pandey et al.
Syed Gulfishan et al.
Breast cancer is among the most prevalent cancers in women and leads to significant mortality worldwide. It remains a global health issue, affecting millions of women annually despite progress in diagnosis and treatment. Advanced-stage brea...
Predicting dynamic changes of Ki-67 in breast cancer after neoadjuvant therapy based on multi-phase DCE-MRI delta-radiomics [0.03%]
基于多时相动态增强MRI差值影像组学预测新辅助治疗后乳腺癌Ki-67变化
Xuan Zhang,Haifeng Zhao,Hao Zhang
Xuan Zhang
Background: Ki-67 is a key biomarker of tumor proliferation in breast cancer. A reduction in Ki-67 following neoadjuvant therapy (NAT) reflects chemosensitivity and holds significant prognostic value. Therefore, pre-treat...
Efficacy and safety of local consolidative therapy combined with systemic therapy in driver-negative oligometastatic non-small cell lung cancer: a systematic review and meta-analysis [0.03%]
驱动基因阴性寡转移非小细胞肺癌局部巩固治疗联合系统治疗的有效性和安全性：系统评价和 Meta 分析
Heqiao Han,Lian Li,Taiwon Park et al.
Heqiao Han et al.
Oligometastatic non-small cell lung cancer (NSCLC) represents a potentially modifiable stage of metastatic disease, however, the survival benefit of local consolidative therapy (LCT) in patients without actionable driver mutations remains u...
Situs inversus totalis and lung cancer: a case report of surgical resection after neoadjuvant chemoimmunotherapy for stage IIIB squamous cell carcinoma [0.03%]
镜面右位心伴肺癌的新辅助化疗免疫治疗后手术一例报告：一期切除术治疗IIIb期鳞癌
Wenhao Wang,Zhouyi Lu,Wan Posum et al.
Wenhao Wang et al.
Immune checkpoint inhibitors (ICIs) have emerged as a promising therapeutic strategy for lung cancer. This case report describes a patient with situs inversus totalis (SIT) and initially unresectable, advanced lung squamous cell carcinoma (...
Zhentao Zhang,Dawei Wang,Feihu Tang et al.
Zhentao Zhang et al.
Objective: To investigate potential diagnostic approaches and therapeutic strategies for renal inflammatory myofibroblastic tumors (IMT). Methods: ...
Comparative analysis of radiation therapy plans before and after biodegradable hydrogel (SpaceOAR) injection for reducing rectal toxicity in patients with prostate cancer undergoing carbon ion radiotherapy [0.03%]
碳离子放疗前列腺癌患者注入可降解水凝胶(SpaceOAR)前后计划对比分析及降低肠道毒性研究
Hyun Jin Kim,Hojin Kim,Sunmi Kim et al.
Hyun Jin Kim et al.
Background: Carbon ion radiotherapy (CIRT) offers superior dose conformity and biological effectiveness, making it an effective modality for treating prostate cancer. However, dose escalation is limited by the anatomical ...