Penile involvement associated with renal pelvic squamous cell carcinoma: a case report and mechanistic considerations [0.03%]
Kotaro Masaki,Takuya Tsujino,Hiroyuki Okada et al.
Kotaro Masaki et al.
Background: Squamous cell carcinoma (SCC) of the renal pelvis is an uncommon malignancy, accounting for less than 1% of upper urinary tract tumors. Penile metastasis from renal pelvic SCC has not been documented. ...
Study on the mechanism of 18β-glycyrrhetinic acid inhibiting the proliferation of renal cancer cells by inducing autophagy through the miR-27a-5p/LC3 axis [0.03%]
Shumin Jia,Lei Zhang,Yahong Li et al.
Shumin Jia et al.
Background: Renal carcinoma is a common, aggressive urinary tract malignancy with notable clinical challenges such as severe treatment toxicity and poor patient outcomes; 18β-glycyrrhetinic acid (18β-GA), an active comp...
Lei P Wang,Bidhan Bhandari,Sahar Emami Naeini et al.
Lei P Wang et al.
Introduction: Glioblastoma (GBM) is an aggressive brain tumor with limited treatment options and poor immune cell infiltration. Although cellular immunotherapies have transformed cancer treatment, they remain largely inef...
Efficacy of sacituzumab govitecan in triple-negative breast cancer with hepatic visceral crisis: a case report [0.03%]
Jiaqi Ye,Jiaang Ye,Huijuan He et al.
Jiaqi Ye et al.
Triple-negative breast cancer (TNBC) is recognized as the most aggressive molecular subtype of breast cancer (BC). The liver is a common site of distant metastasis in BC, and hepatic involvement is associated with accelerated therapeutic re...
A systematic characterization of amino acid metabolism-related genes reveals molecular subtypes and a prognostic signature in bladder cancer [0.03%]
Junrui He,Xu Liu,Shirui Li et al.
Junrui He et al.
Background: Amino acid metabolism is integral to tumor proliferation, redox control, and immune regulation. Yet, studies in bladder cancer have largely centered on single amino acids, leaving the broader metabolic gene ne...
Global, regional and national burden of colon and rectum cancer attributable to high fasting plasma glucose: a systematic analysis for the Global Burden of Disease Study 2021 [0.03%]
Ke Lu,Gang Xu
Ke Lu
Background: Colorectal cancer (CRC), the third most common malignant cancer globally, imposes a substantial public health burden. Emerging evidence has highlighted hyperglycemia as an independent risk factor for CRC. Esti...
Case Report: Furmonertinib dose escalation in heavily pretreated EGFR-mutant lung adenocarcinoma with diffuse brain metastases [0.03%]
Zian Jin,Changhong Dong,Kaiyuan Hui et al.
Zian Jin et al.
Furmonertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, has demonstrated systemic and central nervous system (CNS) antitumor activity in patients with EGFR-mutant non-small cell lung cancer (NSCL...
Development of a second primary tumor during maintenance immunotherapy in metastatic gingival squamous cell carcinoma: a case report [0.03%]
Xiaoyu Liu,Hanquan Sun,Shangzhong Chen et al.
Xiaoyu Liu et al.
Multiple primary tumors are defined as two or more distinct malignancies occurring simultaneously or metachronously in the same patient. This report describes a patient with extensively metastatic gingival squamous cell carcinoma who achiev...
A systematic review and meta-analysis on the prepectoral and partial subpectoral immediate single-stage Implant-Based Breast Reconstruction Using ADM [0.03%]
Tingjian Zhang,Yuyao Liu,Liang Huang et al.
Tingjian Zhang et al.
Introduction: Acellular dermal matrices (ADMs) have made immediate single-stage prepectoral breast reconstruction (PBR) feasible and have promoted the application and development of partial subpectoral breast reconstructi...
A Bayesian network meta-analysis: evaluating the efficacy and safety of targeted therapies in metastatic or advanced radioiodine-refractory differentiated thyroid cancer [0.03%]
Pin Wang,Ling Li,Ying Liu et al.
Pin Wang et al.
Background: Approximately 5%-10% of patients with differentiated thyroid cancer (DTC) develop resistance to radioactive iodine (RAI), leading to unsatisfactory survival rates. The optimal medication for advanced or metast...