Clinical features and prognostic analysis of spontaneous rupture of renal cell carcinoma: a retrospective cohort study [0.03%]
肾细胞癌自发破裂的临床特征和预后分析：一项回顾性队列研究
Shanhua Zhang,Xiaoran Han,Shaoqiu Kong et al.
Shanhua Zhang et al.
Background: Spontaneous rupture of renal cell carcinoma (SRRCC) is a rare but critical clinical manifestation characterized by the acute disruption of tumor integrity, leading to extravasation of tumor contents into the p...
SUNTEL pilot study: first school-based integration of the ugly duckling sign and a dedicated e-learning platform with peer education for melanoma prevention [0.03%]
SUNTENTL研究：首个基于学校的集成丑小鸭征和专门的电子学习平台，并通过同伴教育进行黑色素瘤预防的研究
Ignazio Stanganelli,Serena Magi,Elisabetta Costa et al.
Ignazio Stanganelli et al.
Introduction: Educational initiatives among young people are pivotal in promoting healthy behaviors, yet only a few studies to date have used peer education in schools to convey health messages for melanoma prevention. He...
MRI-based radiomics nomogram for predicting CD8-positive tumor-infiltrating lymphocytes levels in HER2-positive breast cancer [0.03%]
基于MRI的影像组学预测HER2阳性乳腺癌肿瘤浸润淋巴细胞水平的列线图模型
Xiaoguang Li,Qiujie Dong,Chao Cong et al.
Xiaoguang Li et al.
Objective: To develop a radiomics nomogram based on radiomic features derived from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) combined with clinical-imaging characteristics in predicting the CD8+Tumor-...
Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer [0.03%]
一种新型铜依赖性细胞死亡相关基因特征在宫颈癌微环境、预后和治疗反应中的构建及应用研究
Yaqi Cui,Zihan Liu,Lingling Zhang et al.
Yaqi Cui et al.
Introduction: Cervical cancer is a common malignant tumor in females, and its carcinogenesis needs further elucidation. Cuproptosis is a novel mode of cell death and its role in cervical cancer is largely unknown. ...
Ferroptosis's Master Switch GPX4 emerges as universal biomarker for precision immunotherapy: a pan-cancer study with in vitro experiments validation [0.03%]
GPX4铁死亡“主开关”成为精准免疫治疗的普适生物标志物：多癌症类型验证研究及体外实验分析
Xiao Li,Min Zhu,Ruihua Dong
Xiao Li
Introduction: Glutathione peroxidase 4 (GPX4) is a key enzyme in ferroptosis. Gaining insight into GPX4's mechanisms and biological roles could offer valuable therapeutic insights for cancer treatment. ...
Effective vemurafenib monotherapy for refractory Langerhans cell histiocytosis with sustained results post-withdrawal for over two years: a case report [0.03%]
维莫非尼单药治疗朗格汉斯细胞组织细胞增生症疗效显著，停药两年以上仍保持良好疗效——病例报告
Jiaxin Ren,Ling Gu,Xue Tang
Jiaxin Ren
Background: Langerhans cell histiocytosis (LCH) is a rare, inflammatory myeloid neoplasm. Mitogen-activated protein kinase (MAPK) inhibitors, such as vemurafenib, can quickly control active disease in patients resistant t...
Dextran sulfate inhibits the invasion, migration, and programmed death-ligand 1 expression in human gastric cancer cells by affecting the M2 tumor-associated macrophage polarization [0.03%]
葡聚糖硫酸钠通过影响M2型肿瘤相关巨噬细胞极化抑制人类胃癌细胞侵袭、迁移及程序性死亡配体1的表达
Jing Shang,Yuanyi Xu,Yuejia Tao et al.
Jing Shang et al.
Objective: The aim of this study was to investigate the role of dextran sulfate (DS) in M0-to-M2 macrophage polarization and its effect on programmed death-ligand 1 (PD-L1) expression, invasion, migration, proliferation, ...
Giant spontaneous epidermal cyst of the labia minora: a rare case report and literature review [0.03%]
小阴唇巨大自发性表皮囊肿一例并文献复习
Xiang Li,Yuanyuan Bai,Jie Li et al.
Xiang Li et al.
Background: Epidermal cysts are benign subcutaneous masses resulting from the implantation of epithelial cells, following trauma or surgery. Giant spontaneous epidermal cysts of the labia minora are rare. To date, only 3 ...
Clinical characteristics and analysis of cerebrospinal fluid biochemical, tumor markers and cytologic indices in 209 patients with meningeal carcinomatosis: a cross-sectional study [0.03%]
209例脑膜转移患者临床特点及脑脊液生化、肿瘤标志物和细胞学指标分析横断面研究
Shaoqiang Xu,Chunxia Huang,Yuanyang Ye et al.
Shaoqiang Xu et al.
Objective: To analyze the clinical characteristics and cerebrospinal fluid (CSF) biochemical indexes, tumor markers (TM) and cytomorphological indexes of patients with meningeal carcinomatosis (MC), and to explore the cli...
Curcumin triggers reactive oxygen species-mediated apoptosis and suppresses tumor growth in metastatic oral squamous cell carcinoma [0.03%]
姜黄素通过诱导活性氧介导的凋亡抑制转移性口腔鳞状细胞癌的生长
Tarsila de Carvalho Freitas Ramos,Rosane Borges Dias,Luciano de Souza Santos et al.
Tarsila de Carvalho Freitas Ramos et al.
Background: Oral squamous cell carcinoma (OSCC) remains a major clinical challenge with limited effective treatment options. In this context, several natural compounds (NC), such as curcumin, have shown promising effects ...