Biomarkers to optimize PSMA-targeted radioligand therapy for metastatic castration-resistant prostate cancer [0.03%]
PSMA生物标志物优化转移性去势抵抗性前列腺癌放射配体治疗疗效
Himisha Beltran,Jeremie Calais,Louise Emmett et al.
Himisha Beltran et al.
Although the recently approved prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) [177Lu]Lu-PSMA-617 has improved outcomes for patients with metastatic castration-resistant prostate cancer (mCRPC), not all patients...
Minimally invasive surgical treatment for sigmoid colon cancer in a patient with situs inversus totalis: a case report [0.03%]
有关内脏完全反位结肠癌患者微创手术治疗的病例报告
Chao-Yue Zhang,Jing He,Lang-Chao Huang et al.
Chao-Yue Zhang et al.
Situs inversus totalis (SIT) is a rare congenital condition characterized by a complete reversal of the internal organ arrangement, presenting significant surgical challenges. While previous cases of colorectal cancer in SIT patients have b...
Case Report: Hepatic infantile hemangioma malignantly transformed into hemangiosarcoma [0.03%]
个例报告：婴儿型肝血管瘤恶性转化为血管肉瘤
Xiafei Gu,Qing Tao,Zijian Lu et al.
Xiafei Gu et al.
In this study, we retrospectively analyzed the clinicopathological features of a case of hepatic infantile hemangioma (HIH) that malignantly transformed into hemangiosarcoma. HIH, a congenital disease, is the most common benign tumor of the...
Primary vulval sebaceous carcinoma: rare case report and literature review [0.03%]
原发性阴唇皮脂腺癌：罕见病例报告及文献回顾
Kaige Pei,Jiawen Zhang,Mingrong Xi
Kaige Pei
This study presents a rare case of primary vulval sebaceous carcinoma (SC) and a literature review. Sebaceous carcinoma is an aggressive skin malignancy, predominantly periocular, with extraocular cases being particularly uncommon. We detai...
Comprehensive dosimetric comparison of halcyon 3.0 versus truebeam for breast cancer volumetric modulated arc therapy plans [0.03%]
Halcyon和TrueBeam乳腺癌容积旋转调强治疗计划的剂量学综合比较研究
Anyan Gu,Mengyuan Wang,Zhenyu Pan et al.
Anyan Gu et al.
Background: Breast cancer is the foremost malignancy threatening female health. This study aimed to compare the dosimetric performance of Halcyon 3.0 and TrueBeam in Volumetric Modulated Arc Therapy (VMAT) planning for br...
Case Report: Ultrasound-guided interventional diagnosis and treatment of gastrosplenic fistula caused by lymphoma [0.03%]
案例报告：超声引导下淋巴瘤所致胃脾瘘的介入诊治
Yahan Zhang,Yang Li,Manxi Li et al.
Yahan Zhang et al.
Gastrosplenic fistula is a rare complication, most often secondary to gastric or splenic lymphoma. Severe gastrosplenic fistula can cause life-threatening upper gastrointestinal bleeding, making early diagnosis and intervention critical for...
Combined neoadjuvant chemotherapy and immunotherapy in a hepatitis B virus-positive patient with locally advanced rectal adenocarcinoma: a case report and literature review [0.03%]
局部晚期直肠腺癌合并乙型肝炎病毒感染患者术前新辅助化免联合治疗1例及相关文献复习
Qiyun Li,Xue Wu,Zhibin Xu et al.
Qiyun Li et al.
Microsatellite-stable (MSS) rectal adenocarcinoma remains a therapeutic challenge, particularly in patients with complicating factors such as chronic hepatitis B virus (HBV) infection. Advances in immunotherapy, including immune checkpoint ...
Efficacy and safety of radiotherapy combined with immunotherapy and targeted therapy versus immunotherapy plus targeted therapy alone in unresectable hepatocellular carcinoma: a retrospective study [0.03%]
不可切除肝细胞癌患者放疗联合免疫和靶向治疗与单纯免疫和靶向治疗疗效及安全性的回顾性研究
Yanling Yuan,Yongsheng Chen,Chumin Huang et al.
Yanling Yuan et al.
Purpose: To evaluate the efficacy and safety of radiotherapy combined with immunotherapy and targeted therapy (RT+IO+T) versus immunotherapy plus targeted therapy alone (IO+T) in patients with unresectable hepatocellular ...
Dual regulation of gastrointestinal tumor progression by the IFN-γ/STAT1 pathway and prospects for targeted therapy [0.03%]
干扰素γ/信号转导和转录激活因子1通路双重调控胃肠肿瘤发生发展及靶向治疗前景
Yuhao Liu,Yuxin Huang,Qiaoying He et al.
Yuhao Liu et al.
Gastrointestinal malignant tumors exhibit a high incidence and mortality rate among all malignancies worldwide, making them a significant concern within the field of oncology. Targeted therapy for gastrointestinal tumors has become a hot to...
MAPK-targeted therapies in non-gastrointestinal stromal tumor soft tissue sarcomas: current landscape and future directions [0.03%]
软组织肉瘤中针对非胃肠间质瘤的MAPK靶向疗法：现状与未来方向
Ouissam Al Jarroudi,Khalid El Bairi,Sami Aziz Brahmi et al.
Ouissam Al Jarroudi et al.
Non-Gastrointestinal Stromal Tumors (Non-GIST) Soft Tissue Sarcomas (STS) are highly aggressive and challenging diseases with poor prognosis and limited therapeutic options. Molecular profiling is urgently required to gain a deeper understa...