Prognostic biomarker and clinical significance of PLOD gene family in clear cell renal cell carcinoma [0.03%]
PLOD基因家族在透明细胞肾细胞癌中的预后价值及临床意义分析
Xuan Shang,Liu Liu,Zhenwei Yang et al.
Xuan Shang et al.
Background: The PLOD gene family, involved in extracellular matrix (ECM) remodeling, plays a role in tumor progression, but its comprehensive role and clinical significance in clear cell renal cell carcinoma (ccRCC) remai...
Minimally invasive versus open surgery in uterine serous carcinoma: impact on recurrence and survival in a multicenter cohort [0.03%]
一项多中心队列研究：子宫内膜浆液性癌的微创手术与开腹手术对复发及生存的影响
Yi Fang,Jian Chen,Lin Yang et al.
Yi Fang et al.
Background: Uterine serous carcinoma (USC) is a highly aggressive subtype of endometrial cancer, characterized by high recurrence rates and poor prognosis. While minimally invasive surgery (MIS) is commonly used in endome...
Immune-mediated gastritis in a patient with breast cancer due to therapy with immune checkpoint inhibitor pembrolizumab: a case report [0.03%]
派姆单抗免疫检查点抑制治疗乳腺癌所致免疫性胃炎1例报告
Yalan Xu,Junyao Wang,Ning Chen
Yalan Xu
The use of immune checkpoint inhibitors (ICIs) in the treatment of malignant tumors is becoming more widespread, and the management of immune-related adverse events (irAEs) has become an important concern in oncological treatments. Here we ...
Paired DNA/RNA testing uncovers a deep intronic PTEN pathogenic variant associated with clinical Cowden Syndrome: a case report [0.03%]
一对DNA/RNA测序发现与临床Cowden综合征相关的PTEN基因内含子区致病突变：病例报告
Michael J Hall,Dong Won Kim,Devang Namjoshi et al.
Michael J Hall et al.
Identification of a deep intronic PTEN pathogenic variant, which was not detected by standard DNA-targeted panel sequencing but was uncovered by targeted PTEN RNA sequencing using CaptureSeq technology, illustrates the added value of concur...
The cancer-induced lactate load and oncologic remodeling hypothesis: lactate as a driver of biosynthesis and epigenetics in cancer [0.03%]
癌症引起的乳酸负荷和肿瘤重塑假说：乳酸在癌症中的生物合成和表观遗传学驱动作用
Hüseyin Aydin
Hüseyin Aydin
Background: Cancer cells undergo profound metabolic reprogramming to sustain proliferation, redox homeostasis, and epigenetic remodeling. While the Warburg effect and glutaminolysis have long been recognized as central pa...
Prevalence of skin cancers in kidney transplant recipients - one-center experience [0.03%]
肾移植受者皮肤癌的患病率-单中心经验报告
Fabian Kosko,Alicja Dębska-Ślizień,Beata Imko-Walczuk et al.
Fabian Kosko et al.
Introduction: Non-melanoma skin cancers (NMSCs) are the most common neoplasms that occur in solid organ transplant recipients (SOTRs). Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) make up over 90% of skin ...
Active breathing coordinator combines with custom-designed puncture needle improves diagnostic accuracy of ≤20 mm pulmonary nodules under CT-guidance: a real world prospective study [0.03%]
主动呼吸周期配合定制穿刺针可提高≤20mm肺结节的CT引导下诊断准确性：一项前瞻性研究
Yuting Huang,Jie Yang,Peisen Liu et al.
Yuting Huang et al.
Background: CT-guided percutaneous transthoracic needle biopsy (PTNB) is still the main way for obtaining pathological diagnoses of pulmonary nodules. However, the small size and respiratory-induced motion reduce diagnost...
Sawsen Dhambri,Wejdan Mohamed Trabelsi,Rim Braham et al.
Sawsen Dhambri et al.
Background: Primary malignant tumors of the trachea are extremely rare, representing only 0.2% of all respiratory tract tumors. Among them, adenoid cystic carcinoma (ACC) is the second most frequent histological type. Due...
Case Report: Immunophenotypically diverse immature patterns, including variable TdT expression, in aggressive B-cell lymphomas and leukemia with MYC rearrangement [0.03%]
案例报告：MYC重排的侵袭性B细胞淋巴瘤和白血病中多样且不成熟的免疫表型，包括TdT表达的可变性
Daishi Kato,Takahiro Fujino,Reiko Isa et al.
Daishi Kato et al.
This study is a retrospective analysis of our case series and literature review of aggressive B-cell lymphomas with MYC rearrangements that show immunophenotypic immaturity, including expression of terminal deoxynucleotidyl transferase (TdT...
Preoperative prognostic assessment using intratumoral and peritumoral adipose tissue radiomics derived from contrast-enhanced CT in cT3-4 gastric cancer [0.03%]
基于增强CT的肿瘤内和肿瘤周脂肪组织影像组学对cT3-4期胃癌患者术前预后评估的价值研究
Chao Lu,Donggang Pan,Xiuhong Shan et al.
Chao Lu et al.
Purpose: Exploring the value of contrast-enhanced computed tomography (CECT) based radiomics features from intratumoral and peritumoral adipose tissue (PAT) in predicting early recurrence (ER)after gastrectomy in patients...