A real-world 10-year follow-up analysis of survival and safety of CD20-targeted therapy in patients with Waldenstrom macroglobulinemia [0.03%]
Hengming Zhang,Xufei Huang,Yirong Zhu et al.
Hengming Zhang et al.
Objective: To evaluate the long-term survival and safety outcomes of CD20-targeted chemoimmunotherapy regimens in patients with Waldenstrom macroglobulinemia (WM) in a real-world single-center cohort from China. ...
Role of urinary leukocytes in the risk stratification of prostate cancer using nonlinear stacking learning strategy: a bi-cohort diagnostic study [0.03%]
Shou Xia,Zhenchun Ran,Mengzhe Cheng et al.
Shou Xia et al.
Objective: This study aimed to develop a non-linear stacking ensemble learning framework to evaluate the incremental diagnostic contribution of urinary leukocytes (UL) in prostate cancer (PCa) risk stratification, with a ...
Knowledge-based planning for intensity-modulated proton therapy of the breast and chest wall with regional lymph nodes: development, validation, and comparative evaluation of two models [0.03%]
Parker Anderson,Yihang Xu,Robert Kaderka et al.
Parker Anderson et al.
Purpose: Knowledge-based planning (KBP) can improve efficiency and consistency in radiotherapy. In intensity-modulated proton therapy (IMPT) for breast cancer, particularly with regional lymph nodes, treatment planning re...
Xiaoru Gao,Xinru Wang,Xiangfei Wang et al.
Xiaoru Gao et al.
This report describes a clinically rare case of early-stage primary extranodal marginal zone B-cell lymphoma of the prostate. A 73-year-old male presented with urinary hesitancy. Physical examination revealed mild prostatic enlargement. Pro...
Patient-derived cell lines unveil COL1A2 as a predictor of docetaxel resistance in breast cancer [0.03%]
Yuwei Gao,Rong Wang,Xiaowei Dou et al.
Yuwei Gao et al.
Introduction: Breast cancer is the most common malignant tumor among women worldwide and a major cause of cancer-related mortality. Chemoresistance presents a significant challenge in breast cancer therapy and is a primar...
Improving radiation therapy efficacy considering DNA repair, TP53 mutations, microscopic heterogeneity, and low- and high-dose apoptosis [0.03%]
Anders Brahme
Anders Brahme
All radiation types produce δ -rays of about a ≈1 keV or less that can impart MGy doses to 10-nm-size volumes of DNA. These events can produce severe dual double-strand breaks (DDSB) at the periphery of nucleosomes in single events partic...
Commentary: LAT1 expression in head and neck cancer: a prognostic biomarker with potential relevance for BNCT [0.03%]
Xiaobing Liao,Yuanyu Zhu,Changqian Piao et al.
Xiaobing Liao et al.
A novel technique of spacer implantation and proton beam therapy for hilar cholangiocarcinoma: a case report [0.03%]
Wencui Yang,Junetsu Mizoe,Xiaolong Wang
Wencui Yang
The primary treatment for hilar cholangiocarcinoma is a surgical resection. However, most patients have already lost the opportunity for surgical treatment at the time of the initial diagnosis. Photon therapy (X-ray) has limited efficacy, w...
Yujun Tong,Yuzhu Ji,Zhen Zhang et al.
Yujun Tong et al.
Breast metastasis from biliary tract cancer (BTC) is an extremely rare clinical occurrence. We report the case of a 59-year-old woman who was incidentally found to have a hepatic mass, leading to a comprehensive workup prompted by progressi...
Brusatol inhibits metastasis of triple-negative breast cancer through metabolic reprogramming [0.03%]
Xuan Yu,Xueling Diao,Xiaokai Fan et al.
Xuan Yu et al.
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer (BC) characterized by a high risk of metastasis and poor prognosis. Current chemotherapy-based treatments are often limited by sys...