Spatial transcriptome and single-cell sequencing reveal the role of nucleotide metabolism in breast cancer progression and tumor microenvironment [0.03%]
空间转录组和单细胞测序揭示了核苷酸代谢在乳腺癌进展和肿瘤微环境中的作用
Yuejun Pan,Yong Xu,Ke Gong et al.
Yuejun Pan et al.
Background: The complexities of nucleotide metabolism in breast cancer (BC) cells are not yet fully understood. A deeper exploration of the various tumor subpopulations and their interactions with the tumor microenvironme...
Sandip Patil,Rehan Khan,Nemat Ali
Sandip Patil
The expression of mercaptopyruvate sulfurtransferase serves as a potential biomarker for prognostic stratification and immunotherapy in certain cancers [0.03%]
甲硫基丙酮酸硫转移酶的表达可作为某些癌症预后分层和免疫治疗的潜在生物标志物
Boran Cui,Chenchen Xia,Li Yang et al.
Boran Cui et al.
Introduction: 3 - Mercaptopyruvate Sulfurtransferase (3 - MST) is an enzyme encoded by the Mercaptopyruvate Sulfurtransferase (MPST) gene. The enzyme is associated with a variety of cancers such as lung adenocarcinoma. Ho...
In vivo detection of HER2-positive breast cancer and sentinel lymph node metastasis using activatable ICG-conjugated Trastuzumab [0.03%]
用于检测HER2阳性乳腺癌和前哨淋巴结转移的激活型ICG-曲妥珠单抗结合物
Yunpeng Liu,Mahendra Isa,Takahito Nakajima
Yunpeng Liu
Breast cancer continues to pose a significant health threat to women globally, with sentinel lymph node (SLN) metastasis playing a crucial role in treatment planning and prognosis. Conventional diagnostic techniques are invasive, lack dynam...
Patent landscape of nanotechnology - based nucleic acid delivery systems for breast cancer therapies [0.03%]
基于纳米技术的核酸递送系统在乳腺癌治疗中的专利布局分析研究
Milca de Jesus Silva,Katharine Valéria Saraiva Hodel,Larissa Dos Santos Moraes Fonseca et al.
Milca de Jesus Silva et al.
Background: Breast cancer is the most prevalent malignancy among women worldwide and remains a major public health concern. Conventional treatments are often limited by adverse effects and resistance. Nucleic acid-based g...
First-line immune checkpoint inhibitors in older adults (≥75 years) with advanced esophageal squamous cell carcinoma: efficacy and safety [0.03%]
免疫检查点抑制剂一线治疗老年（≥75岁）晚期食管鳞癌患者的疗效和安全性
Lin-Lin Zheng,Yu-Cai Jiang,Dan-Dan Lin
Lin-Lin Zheng
Background: The combination of immune checkpoint inhibitors with chemotherapy is a standard first-line treatment for advanced esophageal squamous cell carcinoma. However, robust data regarding the efficacy and safety of t...
Correction: A structural equation model study on the influencing factors of sleep disorders in patients with breast cancer undergoing chemotherapy [0.03%]
纠正：乳腺癌化疗患者睡眠障碍影响因素结构方程模型研究
Ting Lu,Jiejing Wei,Rongsheng Xiong et al.
Ting Lu et al.
[This corrects the article DOI: 10.3389/fonc.2025.1633763.]. Keywords: breast cancer; chemotherapy; coping s...
Published Erratum
Frontiers in oncology. 2026 Jan 13:16:1768585. DOI:10.3389/fonc.2026.1768585 2026
Correction: PRKCI mediates radiosensitivity via the Hedgehog/GLI1 pathway in cervical cancer [0.03%]
订正：PRKCI通过Hedgehog/GLI1通路介导宫颈癌放敏作用
Zhuna Wu,Chunxian Huang,Ruixin Li et al.
Zhuna Wu et al.
[This corrects the article DOI: 10.3389/fonc.2022.887139.]. Keywords: Hedgehog/GLI1 pathway; PRKCI; auranofi...
Published Erratum
Frontiers in oncology. 2026 Jan 13:16:1765010. DOI:10.3389/fonc.2026.1765010 2026
Unveiling the prognostic role of FABP4 in early-onset colorectal cancer through big data analysis and preliminary clinical validation [0.03%]
基于大数据分析及初步临床验证揭示FABP4在早期结直肠癌预后作用
Yu Wu,Weiwei Zou,Shengjun Zhang et al.
Yu Wu et al.
Background: Early-onset colorectal cancer (EOCRC), characterized by greater aggressiveness and advanced stage at diagnosis, is increasing globally. This study aimed to identify suitable prognostic biomarkers for EOCRC. ...
Mechanotransduction of Piezo1 in the cancer microenvironment: implications for NK cell-based immunotherapy [0.03%]
癌微环境中Piezo1的机械转导：对基于NK细胞免疫治疗的意义
Xinmu Cui,Binbin Zhang,Jianan Zhao et al.
Xinmu Cui et al.
Natural Killer (NK) cells serve a critical function in antitumor immunity. However, their effectiveness is often hampered by the biomechanical properties of the solid tumor microenvironment (TME), such as the stiffness of the extracellular ...