Case Report: Immune-mediated acute liver failure induced by tislelizumab in a patient with advanced cervical cancer [0.03%]
个例报告：替雷利珠单抗致晚期宫颈癌患者急性肝功能衰竭1例
Chaoxia Liu,Xinchun Li,Yuping Deng
Chaoxia Liu
Tislelizumab, an anti-PD-1 monoclonal antibody, is associated with immune-related hepatitis in 1.8% of cases, but reports of acute liver failure (ALF) remain exceedingly rare. We present a case of fulminant hepatitis and ALF following Tisle...
TRIM31 acts as an intermediate molecule in the process by which Snai2 impairs the proliferation of cervical cancer cells [0.03%]
TRIM31作为Snai2抑制宫颈癌细胞增殖过程中的介导分子
Nan Cui,Yanru Zhang,Yuan Zhang et al.
Nan Cui et al.
Snai2 is a transcription factor that inhibits the proliferation of cervical cancer cells and tumor growth. The expression of Snai2 inhibited the expression of β-catenin and impaired Wnt/β-catenin signaling pathway activity. The results of...
Application of low-coverage whole-genome sequencing technology in risk stratification of colorectal adenomas [0.03%]
低覆盖全基因组测序技术在结肠腺瘤风险分层的应用研究
Guo Zhili,Xue Yuyue,Yu Fang et al.
Guo Zhili et al.
Objective: The diagnosis of precancerous lesions of colorectal cancer (CRC) presents significant challenges in clinical practice. In this study, we conducted a clinical investigation using the UCAD technique after analyzi...
Successful treatment of disfiguring facial scar using surgery combined with superficial radiotherapy: a case report with literature review [0.03%]
手术联合浅层放射治疗成功修复面部畸形瘢痕1例及文献复习
Yong-Xia Zong,Yinghua Song,Shuang Deng et al.
Yong-Xia Zong et al.
Introduction: Facial scars are generally disfiguring and can cause both physiological and psychological trauma. Currently, there is a lack of effective treatment options for facial scars. In recent years, local superficia...
Case Report: An azygos vein aneurysm with dysphagia assisted diagnosis by esophageal endoscopic ultrasonography [0.03%]
奇静脉动脉瘤伴吞咽困难的内镜超声检查辅助诊断病例报告
Xueyan Guo,Yuanhang Xu,Yanfei Cao et al.
Xueyan Guo et al.
Background: Azygos vein aneurysm (AVA) is a rare thoracic pathology that is frequently misdiagnosed. While contrast-enhanced chest computed tomography (CT) or magnetic resonance imaging (MRI) can delineate AVA location an...
Case Report: A rare case of hepatoid carcinoma of the ovary with genomic profiling and long-term follow-up: diagnostic and therapeutic perspectives [0.03%]
个案报道：带有基因组分析的卵巢肝样癌罕见病例及长期随访：诊断和治疗视角
Yufang Zuo,Xuan Liu,Yajun Pang et al.
Yufang Zuo et al.
Hepatoid carcinoma of the ovary (HCO) is a highly uncommon and aggressive neoplasm originating from the surface epithelial cells of the ovary, characterized by hepatocyte-like differentiation. To date, most information on HCO is derived fro...
Salvage treatment of a metastatic colorectal cancer with pMMR/MSS in a 21-year-old man: a case report [0.03%]
一例21岁男性pMMR/MSS型转移性结直肠癌挽救治疗的病例报告
Xuesong Li,Hao Liu,Zhuo Yu
Xuesong Li
In metastatic colorectal cancer (mCRC) patients with proficient mismatch repair (pMMR)/microsatellite stability (MSS), beyond third-line therapies were extremely limited. Here, we reported a case of a 21-year-old male patient with pMMR/MSS ...
Spleen EBV-positive inflammatory follicular dendritic cell sarcoma: a case report and literature review [0.03%]
脾EBV阳性炎性滤泡型树突细胞肉瘤1例报告及文献复习
Yi Xiao,Lanlan Li,Xiumei Zhan et al.
Yi Xiao et al.
Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma (EBV+ IFDCS) is a rare tumor that typically arises in the liver or spleen and is characterized by spindle-shaped cells within a dense lymphoplasmacytic background. W...
Burden and trends of ovarian and uterine cancer due to high body mass index from 1990 to 2021: an age-period-cohort study based on the GBD 2021, and projections through 2036 [0.03%]
基于GBD 2021的年龄-时期-队列研究：1990至2021年高体重指数所致卵巢癌及子宫内膜癌疾病负担及趋势分析及至2036年的预测
Bo Yin,Huijuan Zhou
Bo Yin
Background: Ovarian cancer (OC) and uterine cancer (UC) are significant public health concerns among women of reproductive age. High body mass index (BMI) contributes to the increasing burden of these cancers globally, bu...
Role of Meox1 in promoting lung tumor vascularization and impairing CD8+ T cell mediated immunity [0.03%]
Meox1在促进肺肿瘤血管生成和损害CD8+t细胞介导的免疫应答中的作用
Dacheng Yang,Qian Li,Zisheng Chen et al.
Dacheng Yang et al.
Introduction: Endothelial cells play a critical role in tumor-associated vasculature formation and immune modulation, and dysregulation of transcription factors (TFs) such as Meox1 has been associated with various cancers...