The mutational landscape and actionable targets of gallbladder cancer: an ancestry-informed and comparative analysis of a Chilean population [0.03%]
基于祖先信息和比较分析的智利胆囊癌突变图谱和潜在治疗靶点研究
José Ignacio Erices,Evelin González,Marcela Salgado et al.
José Ignacio Erices et al.
Introduction: Gallbladder cancer (GBC) is a highly aggressive malignancy with one of the highest incidence rates reported in Chile. Despite its clinical impact, molecular characterization of GBC in Latin American populati...
Jie Yang,Wei Liu,Jie An et al.
Jie Yang et al.
Primary breast leiomyosarcoma is an extremely rare malignancy originating from mesenchymal tissue. Fewer than 10 male cases have been reported globally. This paper reports an 84-year-old male patient. This represents the oldest reported cas...
Case Report: Retroperitoneal bronchogenic cyst mimicking adrenal mass: Clinical implications and comprehensive literature analysis [0.03%]
病例报告：腹膜后支气管源性囊肿误诊为肾上腺占位的临床意义及全面文献分析
Shengxiang Xiang,Jiange Hao,Xiaowen Zong et al.
Shengxiang Xiang et al.
Background: Bronchogenic cysts are benign congenital anomalies originating from embryonic foregut development. Although typically located in the mediastinum or lung parenchyma, retroperitoneal bronchogenic cysts are excee...
Current quality of life questionnaires are not relevant for assessing QOL issues in multiple myeloma patients in the era of modern therapies: results from a survey with myeloma patients and myeloma healthcare professionals [0.03%]
当前的生活质量问卷对于评估多发性骨髓瘤患者在现代治疗时代的生存质量问题并不相关：一项关于骨髓瘤患者的调查结果及对骨髓瘤医疗专业人员的调查结果
Catherine S Y Lecat,Sotirios Bristogiannis,Dipal Mehta et al.
Catherine S Y Lecat et al.
As multiple myeloma (MM) patients live longer, maintaining quality of life (QOL) has become an important treatment goal. However, the commonly used general quality of life questionnaires (QOLQs) were developed over 20 years ago. In this sur...
MDA-MB-231 breast cancer cells adapted to anchorage-independent growth reveal senescent-like phenotype and persistent downregulation of PD-L1 expression [0.03%]
适应无锚定生长的MDA-MB-231乳腺癌细胞表现出类似衰老的表型并持续下调PD-L1表达
Tadeja Snedec,Jernej Repas,Darin Lah et al.
Tadeja Snedec et al.
Introduction: Metastasis remains the primary cause of mortality in breast cancer, particularly in aggressive triple-negative (TNBC) subtypes. A crucial yet understudied aspect of this process involves cancer cell survival...
Establishment and validation of a nomogram model for predicting early death in patients with endometrial cancer bone metastases [0.03%]
内膜癌骨转移患者早期死亡预测nomogram模型的建立和验证
Qi Tang,Yating Sun,Yingchun Gao
Qi Tang
Background: Patients with endometrial cancer bone metastases (ECBM) are clinically rare and have a poor prognosis, including a higher incidence of early death (survival ≤ 3 months). Currently, no practical tools exist to...
A preoperative prediction model for ipsilateral axillary lymph node metastasis of breast cancer based on clinicopathological and ultrasonography features: a prospective cohort study [0.03%]
基于临床病理和超声特征的乳腺癌同侧腋窝淋巴结转移术前预测模型：前瞻性队列研究
Xinyi Guo,Yue Ling,Yulan Peng et al.
Xinyi Guo et al.
Background: For breast cancer, developing non-invasive methods to accurately predict axillary lymph node (ALN) status before surgery has become a general trend. This study aimed to develop and evaluate a nomogram to predi...
Early postoperative enteral nutrition and its impact on postoperative recovery in gastrointestinal tumor surgery [0.03%]
早期肠内营养对胃肠肿瘤手术患者术后恢复的影响研究
Peng-Hua Weng,Yan Du,Feng Yuan
Peng-Hua Weng
Background: Surgeries for gastrointestinal tumors frequently result in considerable postoperative complications, such as surgical site infections (SSIs) and impaired nutritional parameters. This study focuses on the role ...
Case Report: Shadows of disappearance: the enigma of completely regressed cutaneous melanoma revealed by lymph node metastasis [0.03%]
个例报告：消失的阴影：完全消退的皮肤黑色素瘤因淋巴结转移而真相大白
Li Wang,Yingxue Li,Xinyan Zhang et al.
Li Wang et al.
Primary cutaneous malignant melanoma is an aggressive neoplasm with high metastatic potential. Complete spontaneous regression of the primary lesion is rare, poorly understood, and often leads to diagnostic challenges, particularly when the...