Pencil beam scanning proton lattice radiotherapy: single-field versus multi-field optimization [0.03%]
单野优化与多野优化的质子层析笔形束扫描治疗的射束线型研究
Shouyi Wei,Lee Xu,Hang Qi et al.
Shouyi Wei et al.
Objective: To evaluate the advantages and disadvantages of single-field versus multi-field optimization in the clinical implementation of pencil beam scanning (PBS) proton lattice radiotherapy (LRT). ...
Dosimetric impact of bolus thickness and immobilization mask use in postmastectomy radiotherapy: a chest wall thickness-based analysis [0.03%]
乳房切除术后放射治疗中衬垫厚度和固定面膜使用的剂量影响:基于胸壁厚度的分析
Qing-Jun Shang,Meng Zhang,Bing-Xin Zhao et al.
Qing-Jun Shang et al.
Purpose: Postmastectomy radiotherapy (PMRT) requires a balance between optimal target coverage and organ-at-risk (OAR) sparing. Thermoplastic masks and different bolus thicknesses are frequently applied in clinical practi...
Long-term survival in extensive-stage small cell lung cancer: a case report on the integration of interventional bronchoscopy and systemic immunotherapy [0.03%]
广泛期小细胞肺癌长期生存的病例报告——经支气管介入技术联合系统性免疫治疗的应用
Ganxiu Deng,Shixuan Yan,Victor Bwembya et al.
Ganxiu Deng et al.
Small cell lung cancer (SCLC) is an aggressive malignancy with a poor prognosis, particularly in patients with extensive-stage disease (ES-SCLC). Although the incorporation of immune checkpoint inhibitors (ICIs) into first-line chemotherapy...
Identification of endogenous reference genes for RT-qPCR analysis in breast cancer and matched adjacent tissues [0.03%]
鉴定乳腺癌及其匹配邻近组织RT-qPCR分析的内源参照基因
Yue Meng,Ya-Wen Wang,Zhi-Bao Xu et al.
Yue Meng et al.
Background: Real-time quantitative PCR (RT-qPCR), essential for gene expression and biomarker studies, requires stable endogenous reference genes (RGs) for normalization. This study aimed to identify consistently expresse...
Case Report: Case of Wernicke's encephalopathy complicated by postoperative gastroparesis following sigmoid colon malignant tumor surgery with a literature review [0.03%]
个案报告:结肠癌术后胃轻瘫所致的Wernicke脑病1例及相关文献回顾
Zhengpeng Qian,Dewang Wu,Chengzhang Zhu et al.
Zhengpeng Qian et al.
Objective: To explore the pathogenesis, clinical characteristics, and key points of the diagnosis and treatment of postoperative gastroparesis (POG) complicated by Wernicke's encephalopathy (WE) after sigmoid colon malign...
A rare cytogenetically cryptic MECOM rearrangement in a patient with myelodysplastic neoplasm and SF3B1 mutation identified by RNA sequencing: a case report [0.03%]
RNA测序鉴定SF3B1突变的骨髓形态学异常肿瘤患者中罕见的分子遗传学MECOM重排:病例报告
Ye Jin,Zi-Jun Xu,Chao-Ran Lv et al.
Ye Jin et al.
MECOM (the MDS1 and EVI1 complex locus) rearrangements have been identified as an independent high-risk factor in acute myeloid leukemia (AML). The diversity of MECOM rearrangement partner genes significantly influences disease mechanisms a...
Intratumoral habitat and peritumor radiomics for progression risk stratification of patients with soft tissue sarcoma: a multicenter study [0.03%]
软组织肉瘤患者肿瘤内生境和肿瘤周影像组学用于复发风险分层的多中心研究
Hao-Yu Liang,Chuan-Ping Gao,Meng Zhang et al.
Hao-Yu Liang et al.
Objective: To establish and validate a radiomics nomogram that incorporated tumor habitat and peritumor features to predict tumor progression in patients with soft tissue sarcoma (STS). ...
Case Report: The double-edged sword: cytokine release syndrome and rapid tumor response in a patient treated with amivantamab and chemotherapy [0.03%]
个例报告:双刃剑——接受Amivantamab和化疗治疗的患者的细胞因子释放综合征和快速肿瘤反应
Pengfei Cui,Guannan Sun,Gang Zhou et al.
Pengfei Cui et al.
Objective: To report a well-documented case of cytokine release syndrome (CRS) following the first cycle of amivantamab combined with chemotherapy in a patient with osimertinib-resistant EGFR-mutant non-small cell lung ca...
Case Report: Personalized management of HER2-positive breast cancer with advanced nodal disease during pregnancy: a clinical case and review [0.03%]
个例报告:妊娠期间HER2阳性乳腺癌伴晚期淋巴结疾病的个性化管理:临床病例与综述
Carla Gullotta,Benjamin Walbaum,Elia Seguí et al.
Carla Gullotta et al.
Background: Pregnancy-associated breast cancer (PrBC) poses complex challenges in diagnosis and treatment, particularly when associated with biologically aggressive subtypes and extensive nodal involvement. Management mus...
An integrated AI-enabled system using One Class Twin Cross Learning for early gastric cancer detection [0.03%]
一种基于One Class Twin Cross Learning的AI集成系统在早期胃癌检测中的应用研究
Xian-Xian Liu,Yuanyuan Wei,Yongze Guo et al.
Xian-Xian Liu et al.
Background: Early detection of gastric cancer, a leading cause of cancer-related mortality worldwide, remains significantly hampered by the limitations of current diagnostic technologies, resulting in high rates of misdia...