Active breathing coordinator combines with custom-designed puncture needle improves diagnostic accuracy of ≤20 mm pulmonary nodules under CT-guidance: a real world prospective study [0.03%]
主动呼吸周期配合定制穿刺针可提高≤20mm肺结节的CT引导下诊断准确性：一项前瞻性研究
Yuting Huang,Jie Yang,Peisen Liu et al.
Yuting Huang et al.
Background: CT-guided percutaneous transthoracic needle biopsy (PTNB) is still the main way for obtaining pathological diagnoses of pulmonary nodules. However, the small size and respiratory-induced motion reduce diagnost...
Sawsen Dhambri,Wejdan Mohamed Trabelsi,Rim Braham et al.
Sawsen Dhambri et al.
Background: Primary malignant tumors of the trachea are extremely rare, representing only 0.2% of all respiratory tract tumors. Among them, adenoid cystic carcinoma (ACC) is the second most frequent histological type. Due...
Case Report: Immunophenotypically diverse immature patterns, including variable TdT expression, in aggressive B-cell lymphomas and leukemia with MYC rearrangement [0.03%]
案例报告：MYC重排的侵袭性B细胞淋巴瘤和白血病中多样且不成熟的免疫表型，包括TdT表达的可变性
Daishi Kato,Takahiro Fujino,Reiko Isa et al.
Daishi Kato et al.
This study is a retrospective analysis of our case series and literature review of aggressive B-cell lymphomas with MYC rearrangements that show immunophenotypic immaturity, including expression of terminal deoxynucleotidyl transferase (TdT...
Preoperative prognostic assessment using intratumoral and peritumoral adipose tissue radiomics derived from contrast-enhanced CT in cT3-4 gastric cancer [0.03%]
基于增强CT的肿瘤内和肿瘤周脂肪组织影像组学对cT3-4期胃癌患者术前预后评估的价值研究
Chao Lu,Donggang Pan,Xiuhong Shan et al.
Chao Lu et al.
Purpose: Exploring the value of contrast-enhanced computed tomography (CECT) based radiomics features from intratumoral and peritumoral adipose tissue (PAT) in predicting early recurrence (ER)after gastrectomy in patients...
Clinical features and prognostic analysis of spontaneous rupture of renal cell carcinoma: a retrospective cohort study [0.03%]
肾细胞癌自发破裂的临床特征和预后分析：一项回顾性队列研究
Shanhua Zhang,Xiaoran Han,Shaoqiu Kong et al.
Shanhua Zhang et al.
Background: Spontaneous rupture of renal cell carcinoma (SRRCC) is a rare but critical clinical manifestation characterized by the acute disruption of tumor integrity, leading to extravasation of tumor contents into the p...
SUNTEL pilot study: first school-based integration of the ugly duckling sign and a dedicated e-learning platform with peer education for melanoma prevention [0.03%]
SUNTENTL研究：首个基于学校的集成丑小鸭征和专门的电子学习平台，并通过同伴教育进行黑色素瘤预防的研究
Ignazio Stanganelli,Serena Magi,Elisabetta Costa et al.
Ignazio Stanganelli et al.
Introduction: Educational initiatives among young people are pivotal in promoting healthy behaviors, yet only a few studies to date have used peer education in schools to convey health messages for melanoma prevention. He...
MRI-based radiomics nomogram for predicting CD8-positive tumor-infiltrating lymphocytes levels in HER2-positive breast cancer [0.03%]
基于MRI的影像组学预测HER2阳性乳腺癌肿瘤浸润淋巴细胞水平的列线图模型
Xiaoguang Li,Qiujie Dong,Chao Cong et al.
Xiaoguang Li et al.
Objective: To develop a radiomics nomogram based on radiomic features derived from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) combined with clinical-imaging characteristics in predicting the CD8+Tumor-...
Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer [0.03%]
一种新型铜依赖性细胞死亡相关基因特征在宫颈癌微环境、预后和治疗反应中的构建及应用研究
Yaqi Cui,Zihan Liu,Lingling Zhang et al.
Yaqi Cui et al.
Introduction: Cervical cancer is a common malignant tumor in females, and its carcinogenesis needs further elucidation. Cuproptosis is a novel mode of cell death and its role in cervical cancer is largely unknown. ...
Ferroptosis's Master Switch GPX4 emerges as universal biomarker for precision immunotherapy: a pan-cancer study with in vitro experiments validation [0.03%]
GPX4铁死亡“主开关”成为精准免疫治疗的普适生物标志物：多癌症类型验证研究及体外实验分析
Xiao Li,Min Zhu,Ruihua Dong
Xiao Li
Introduction: Glutathione peroxidase 4 (GPX4) is a key enzyme in ferroptosis. Gaining insight into GPX4's mechanisms and biological roles could offer valuable therapeutic insights for cancer treatment. ...
Effective vemurafenib monotherapy for refractory Langerhans cell histiocytosis with sustained results post-withdrawal for over two years: a case report [0.03%]
维莫非尼单药治疗朗格汉斯细胞组织细胞增生症疗效显著，停药两年以上仍保持良好疗效——病例报告
Jiaxin Ren,Ling Gu,Xue Tang
Jiaxin Ren
Background: Langerhans cell histiocytosis (LCH) is a rare, inflammatory myeloid neoplasm. Mitogen-activated protein kinase (MAPK) inhibitors, such as vemurafenib, can quickly control active disease in patients resistant t...