Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data [0.03%]
通过整合批量和单细胞RNA测序数据揭示NK细胞在肝癌预后中的异质性
Jiashuo Li,Zhenyi Liu,Gongming Zhang et al.
Jiashuo Li et al.
Background: The tumor microenvironment (TME) plays a critical role in the development, progression, and clinical outcomes of hepatocellular carcinoma (HCC). Despite the critical role of natural killer (NK) cells in tumor ...
Spatial genomics reveals cholesterol metabolism as a key factor in colorectal cancer immunotherapy resistance [0.03%]
空间组学揭示胆固醇代谢是结直肠癌免疫治疗耐药的关键因素
Andrew J Kavran,Yulong Bai,Brian Rabe et al.
Andrew J Kavran et al.
Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape across multiple cancer types achieving durable responses for a significant number of patients. Despite their success, many patients still fail to respond to ICIs o...
Global and East Asia tracheal, bronchus, and lung cancer trend analysis from 1990 to 2021 and forecast trend from 2021 to 2035 [0.03%]
1990年至2021年全球及东亚肺癌发病趋势分析及2021至2035年发病率预测报告
Jian Ding,Weizhen Guo,Qian Xue et al.
Jian Ding et al.
Background and aims: This study aimed to evaluate the trends in incidence, mortality, and disability-adjusted life years (DALYs) for trachea, bronchus, and lung (TBL) cancer globally and in East Asia from 1990 to 2021. ...
Analysis of the safety and efficacy of laparoscopic gastrojejunostomy following neoadjuvant chemotherapy for gastric pyloric obstruction [0.03%]
新辅助化疗后胃癌幽门梗阻患者行腹腔镜下胃肠吻合术的疗效及安全性分析
Bo Hu,Yishan Zeng
Bo Hu
Objective: To explore the safety and feasibility of laparoscopic gastrojejunostomy combined with neoadjuvant chemotherapy (NACT) in patients with locally advanced gastric cancer and pyloric obstruction. ...
A nomogram based on quantitative MR signal intensity predicts early response to combined systemic treatment in patients with hepatocellular carcinoma [0.03%]
基于定量MR信号强度的诺模图预测肝癌综合系统治疗早期疗效
Ran Tao,Haohao Lu,Xiangjun Dong et al.
Ran Tao et al.
Objective: This study aimed to develop and evaluate the value of a nomogram based on quantitative MR signal intensity to predict response to combined systemic therapy of anti-angiogenesis and immune checkpoint inhibitor (...
Lateral retroperitoneal approach for the treatment of a recumbent silkworm-like paravertebral schwannoma in the lumbar spine: a case report [0.03%]
俯卧经后腰横行入路手术治疗腰椎旁神经膜瘤1例报告
Lanming Su,Wei Liu,Yingying Zhang et al.
Lanming Su et al.
Objective: This case report describes the surgical management of a recumbent silkworm-like paravertebral schwannoma in the lumbar spine resected via the lateral retroperitoneal approach. ...
Malignant Wolffian adnexal tumor in the ovary: a case report and literature review [0.03%]
卵巢恶性 Wolff 综合征附件肿瘤一例并文献复习
Cheng Chi,Guoliang Li,Zian Zheng et al.
Cheng Chi et al.
Background: Wolffian adnexal tumor (WAT) is a rare neoplasm originating from the remnants of the Wolffian duct (mesonephric duct). Malignant WAT occurring in the ovary is exceptionally uncommon. This article presents a ca...
Pseudouridine synthase 1 promotes progression of hepatocellular carcinoma via mTOR and MYC signaling pathways [0.03%]
假尿苷合成酶1通过mTOR和MYC信号通路促进肝细胞癌的发展进展
Li Chen,Yonghuang Tan,Weinan Li et al.
Li Chen et al.
Pseudouridine synthases (PUSs) are associated with the development and progression of various cancers. However, the role of pseudouridine synthase 1 (PUS1) on HCC is unclear. The purpose of this study is to explore the biological role and m...
Global, regional, and national burden of myelodysplastic syndromes and myeloproliferative neoplasms, 1990-2021: an analysis from the global burden of disease study 2021 [0.03%]
1990年至2021年全球、区域和国家层面的骨髓增生异常综合征及骨髓增殖性肿瘤疾病负担：来自2021年全球疾病负担研究的分析结果
Xinyue Gou,Zhuo Chen,Yudi Shangguan
Xinyue Gou
Objective: To analyze the trends and cross-country inequalities in the burden of Myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN) over the past 30 years and forecast potential changes through 2045. ...
Prognostic and clinicopathological value of the controlling nutritional status score in patients with multiple myeloma: a meta-analysis [0.03%]
控制性营养状态评分在多发性骨髓瘤患者中的预后和临床病理价值：一项系统评价和meta分析
Yin Jin,Wenfei Gu
Yin Jin
Background: The effect of the controlling nutritional status (CONUT) score on forecasting multiple myeloma (MM) prognosis is previously analyzed, whereas the results remained inconsistent. The present meta-analysis focuse...