Association of B7H3 with HIF-1α nuclear expression indicates poor prognosis and therapeutic potential in gastric cancer [0.03%]
B7H3与HIF-1α核表达相关，提示胃癌患者预后不良及治疗潜力
Mengsi Li,Tianwei Guo,Ziyi Wang et al.
Mengsi Li et al.
B7H3 (B7 homolog 3) is an important immune checkpoint molecule in the B7-CD28 family, and substantial evidence indicates that it promotes tumor growth, invasion, and metastasis. The imbalance between oxygen supply and consumption in the tum...
Interpretable ADC-based radiomics models for differentiating hepatocellular carcinoma and intrahepatic cholangiocarcinoma [0.03%]
基于ADC的可解释性影像组学模型鉴别肝细胞癌和肝内胆管癌
Yun Zhang,Xiao Yin,Baowen Guo et al.
Yun Zhang et al.
Objective: This study aimed to develop interpretable machine learning (ML) models using apparent diffusion coefficient (ADC) radiomics to differentiate hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (...
Multimodal imaging techniques in Yttrium-90 radioembolization for hepatocellular carcinoma: a modality-oriented clinical review [0.03%]
放射性微球选择内照射治疗肝细胞癌的多模式影像技术临床研究进展综述
Tingting Yang,Lijie Zhang,Wei Xu et al.
Tingting Yang et al.
Hepatocellular carcinoma (HCC) is one of the most common malignancies with high global mortality. Yttrium-90 selective internal radiation therapy (90Y-SIRT) is a precision radio-interventional treatment whose efficacy and safety critically ...
Construction of a prediction model for axillary lymph node metastasis in stage cN0 hormone receptor-positive breast cancer: based on interpretable machine learning methods [0.03%]
基于可解释机器学习方法构建cN0期激素受体阳性乳腺癌腋窝淋巴结转移预测模型
Wenyan Liu,Zhijun Ma,Yufei Wang et al.
Wenyan Liu et al.
Background: Accurately predicting axillary lymph node metastasis (ALNM) preoperatively is crucial for optimizing management in patients with clinically node-negative (cN0) hormone receptor-positive (HR+) breast cancer (BC...
Impact of total gastrectomy plus perioperative PD-1 inhibitors on survival in locally advanced gastric cancer [0.03%]
全胃切除术加围手术期PD-1抑制剂对局部进展期胃癌生存影响的研究
Fan Zhang,Min Huang
Fan Zhang
Background: The prognosis for locally advanced gastric cancer (LAGC) remains suboptimal with standard perioperative chemotherapy. Integrating PD-1 inhibitors into this regimen is a promising strategy requiring further val...
Single-incision laparoscopic surgery with transabdominal postperitoneal approach for synchronous ileocecal and sigmoid cancers: a case report [0.03%]
经腹膜后途径单孔腹腔镜同步回结肠癌和 sigmoid 癌手术一例报告
Junyi Li,Ruijie Lin,Jin Tang et al.
Junyi Li et al.
Surgical operation is the most commonly used treatment for colorectal cancer, and the treatment of synchronous multiple primary colorectal cancer is also mainly based on surgical operation. Retroperitoneal Approach for total colectomy in mi...
Surgical and survival outcomes of neoadjuvant IMRT-based chemoradiotherapy versus upfront surgery in borderline resectable pancreatic cancer: a retrospective cohort study [0.03%]
新辅助放化疗联合手术与初始手术治疗临界可切除胰腺导管腺癌的手术及生存结局：一项回顾性队列研究
Xinru Huang,Hui Yang,Wentao Cai
Xinru Huang
Background: Borderline resectable pancreatic cancer (BRPC) poses significant surgical challenges due to tumor-vessel involvement and high risk of positive margins and early recurrence. While neoadjuvant chemoradiotherapy ...
Metabolic remodeling and immune evasion in glioblastoma: a focus on serine and lipid networks [0.03%]
胶质母细胞瘤中的代谢重塑和免疫逃逸：丝氨酸和脂质网络的研究焦点
Dongxin Jiang,Chuheng Wang,Yao Zhao et al.
Dongxin Jiang et al.
Glioblastoma (GBM) is a highly aggressive brain tumor characterized by metabolic plasticity that fuels growth, therapy resistance, and immune evasion. Among its reprogrammed pathways, serine and lipid metabolism play central roles. The seri...
Accuracy of ctDNA-based minimal residual disease detection in predicting postoperative recurrence of breast cancer: a meta-analysis [0.03%]
基于ctDNA的最小残余疾病检测预测乳腺癌术后复发的准确性：一项荟萃分析
Hang You,JiuJiang He,Tian Tian
Hang You
Background: Detection of circulating tumor DNA (ctDNA) has attracted growing attention for predicting postoperative breast cancer recurrence; however, the differences between the landmark and surveillance strategies remai...
Immunotherapy and tyrosine kinase inhibitors in chordoma: a real-world data study from a European Reference Network on Rare Adult Solid Cancers member center [0.03%]
免疫疗法和酪氨酸激酶抑制剂在软骨肉瘤中的应用：欧洲罕见成人实体肿瘤参考网络成员中心的现实世界数据研究
Mario Balsa,Francesc Torrent,Diana Pérez et al.
Mario Balsa et al.
Introduction: Chordoma is a rare malignant tumor originating in the notochord characterized by slow progression but frequent recurrences. Systemic treatment for this condition is not well defined. This study aimed to desc...