A case report of advanced pancreatic cancer patient demonstrating remarkable efficacy with liposomal irinotecan after failure of multiple-line therapies [0.03%]
多线治疗失败后的脂质体伊立替康治疗晚期胰腺癌的疗效观察——1例报告
Siyu Yu,Hong Zhu
Siyu Yu
Pancreatic cancer remains one of the most aggressive malignancies with an exceptionally poor prognosis. We herein report a case of a 53-year-old male diagnosed with pancreatic tail adenocarcinoma accompanied by extensive hepatic metastases....
Anti-HPV gel versus interferon α-2b gel as adjuvant therapy after LEEP for HSIL with HR-HPV infection on clinical outcomes, vaginal microecology, and biomarkers of proliferation and immunity [0.03%]
针对HR-HPV感染HSIL患者LEEP术后两种辅助治疗对临床结局、阴道微生态及增殖和免疫相关生物标志物的影响研究:利可君凝胶与干扰素凝胶的对比研究
Xu Long,Mengjun Luo,Chunrong Yang et al.
Xu Long et al.
Objective: To evaluate and compare the efficacy, impact on vaginal microbiota, changes in inflammatory/immune/proliferation biomarkers, and safety profile of Anti-HPV gel versus Interferon α-2b gel as adjuvant therapies ...
Generation of NBS1 knockout in Chinese hamster cells revealed ATR role for radiation and etoposide induced DNA damage in absence of NBS1 proteins [0.03%]
NBS1基因敲除细胞的构建及NBS1蛋白缺失时辐射和表阿霉素所致DNA损伤的作用研究
Gamze Badakul,Junko Maeda,Takamitsu A Kato
Gamze Badakul
Nijmegen Breakage Syndrome (NBS) is a rare autosomal recessive disorder characterized by chromosomal instability, immunodeficiency, radiosensitivity, and a strong predisposition to lymphoid malignancies. It is caused by mutations in the NBN...
Radiotherapy for low grade gliomas in children with neurofibromatosis type 1: when there is no other choice. Case Report [0.03%]
NF1儿童低级别胶质瘤的放射治疗——别无选择时。病例报告
Serafin Castellano-Damaso,Felisa Vazquez-Gomez,Marta Perez-Somarriba et al.
Serafin Castellano-Damaso et al.
Radiotherapy for low-grade gliomas (LGG) in neurofibromatosis type 1 (NF1) is normally avoided, since these children are at an elevated risk of developing severe sequelae. NF1 patients are more predisposed to developing radiation-induced ma...
Safety recommendations for ALK tyrosine kinase inhibitors in non-small cell lung cancer: evidence from FAERS and CVARDD real-world databases [0.03%]
来自真实世界数据库的ALK酪氨酸激酶抑制剂非小细胞肺癌安全用药建议：来自主动监测报告系统和综合验证与可扩展挖掘的真实世界数据库的证据
Yuanyuan Zhang,Tuanzhuang Zhang,Yuping Yang et al.
Yuanyuan Zhang et al.
Background: Non-small cell lung cancer (NSCLC) remains one of the leading causes of cancer mortality worldwide. The development of anaplastic lymphoma kinase tyrosine kinase inhibitors (ALK-TKIs) has significantly improve...
Primary malignant melanoma of the uterine cervix: a case report of aggressive progression despite multimodal therapy [0.03%]
原发性宫颈恶性黑色素瘤的一例报告及治疗经验
Qing Yu
Qing Yu
Objective: Primary malignant melanoma of the uterine cervix is an exceptionally rare malignancy with a biology distinct from its cutaneous counterpart and a dire prognosis. This case provides a critical in vivo model for ...
Advancing radiation oncology care in Ukraine during the war: impact of international observerships on professional development and clinical practice [0.03%]
战争期间乌克兰放射肿瘤学护理的推进：国际观察员计划对专业发展和临床实践的影响
Yuliia Lozko,Andriy Beznosenko,Natalka Suchowerska et al.
Yuliia Lozko et al.
Objective: This study evaluates the impact of international observerships organized by Help Ukraine Group (HUG) on professional development, knowledge transfer, and clinical practice improvement in radiation oncology in U...
Global hotspots and trends in the application of neoadjuvant therapy for gastric cancer: a bibliometric analysis [0.03%]
胃癌新辅助治疗应用的全球热点和趋势：一次计量学分析
Zhongke Wang,Lingzu Kong,Tian-Yu Jiang et al.
Zhongke Wang et al.
Objective: Neoadjuvant therapy (NAT) is increasingly being applied in gastric cancer (GC) and is recognized by international guidelines. This study aims to analyze the current status, hotspots, and research trends of NAT ...
Comparative efficacy of aerobic exercise and mind-body practices in improving sleep quality and psychological distress among elderly breast cancer patients: a systematic review [0.03%]
有氧运动和身心练习改善老年乳腺癌患者睡眠质量和心理困扰的疗效比较：系统综述
Cai Cui,Wei Liang,Xin Liu
Cai Cui
Elderly breast cancer patients often face severe sleep disturbances and psychological distress due to the disease itself and its treatment process, significantly reducing their quality of life. In recent years, non-pharmacological intervent...
Evolving treatment strategies for HER2-altered non-small-cell lung cancer: the rise of TKIs and ADCs [0.03%]
HER2改变的非小细胞肺癌治疗策略的演变：TKI和ADC的崛起
Sevinc Balli,Tugba Basoglu,Mustafa Ozdogan
Sevinc Balli
Human epidermal growth factor receptor 2 (HER2) is an actionable oncogenic driver in a small subset of non-small cell lung cancer (NSCLC), occurring as gene mutations and less frequently as gene amplification or protein overexpression. Unti...